antimitotic

简明释义

英[ˌæntɪmaɪˈtɒtɪk]美[æntɪˈmaɪtɑːtɪk]

adj. 抗有丝分裂的

英英释义

单词用法

同义词

反义词

例句

1.It was found that 303(29.1%) strains of marine microorganisms had antimicrobial activity and 219(21.0%) strains had antimitotic activity.

抗稻瘟霉分生孢子活性菌株219株，活性菌株分离率为21.0%。

2.It was found that 303(29.1%) strains of marine microorganisms had antimicrobial activity and 219(21.0%) strains had antimitotic activity.

抗稻瘟霉分生孢子活性菌株219株，活性菌株分离率为21.0%。

3.Some plants produce natural antimitotic compounds that can inhibit cell division.

一些植物产生天然的抗有丝分裂化合物，可以抑制细胞分裂。

4.Patients receiving antimitotic therapy often experience side effects like nausea.

接受抗有丝分裂治疗的患者常常经历如恶心等副作用。

5.The study revealed that the antimitotic agent effectively slowed down tumor growth.

研究显示，该抗有丝分裂剂有效减缓了肿瘤生长。

6.The mechanism of action for this antimitotic drug involves disrupting microtubule formation.

这一抗有丝分裂药物的作用机制涉及破坏微管的形成。

7.The research focused on the development of new antimitotic drugs to combat cancer.

该研究专注于开发新的抗有丝分裂药物以对抗癌症。

作文

In the realm of medicine and biology, the term antimitotic refers to a class of substances that inhibit or disrupt the process of mitosis, which is the division of a cell into two daughter cells. The significance of antimitotic agents cannot be overstated, especially in the context of cancer treatment. Cancer cells often exhibit uncontrolled growth and division, leading to tumor formation. Therefore, the use of antimitotic drugs can be a crucial strategy in slowing down or stopping the proliferation of these malignant cells.One of the most well-known categories of antimitotic agents includes the taxanes, such as paclitaxel and docetaxel. These drugs work by stabilizing microtubules, structures essential for chromosome separation during cell division. By preventing the normal breakdown of these microtubules, antimitotic agents effectively halt the cell cycle, forcing cancer cells to remain in a state of non-division. This mechanism is particularly useful in treating various types of cancers, including breast, lung, and ovarian cancers.Another important group of antimitotic agents is the vinca alkaloids, which include vincristine and vinblastine. Unlike taxanes, vinca alkaloids inhibit the assembly of microtubules, disrupting the formation of the mitotic spindle necessary for cell division. This disruption leads to cell death, particularly in rapidly dividing cells, which is a hallmark of many cancerous tumors. The effectiveness of antimitotic drugs has made them a staple in chemotherapy regimens, often used in combination with other therapeutic agents to enhance their efficacy.While the benefits of antimitotic agents are clear, it is also important to consider their side effects. Because these drugs target rapidly dividing cells, they can also affect healthy tissues that undergo frequent cell division, such as those in the bone marrow, gastrointestinal tract, and hair follicles. This can lead to common side effects such as nausea, vomiting, hair loss, and an increased risk of infections due to decreased white blood cell counts. Understanding these side effects is crucial for healthcare providers to manage patient care effectively during treatment.Research continues to explore new antimitotic agents and combinations that may improve outcomes while minimizing adverse effects. Novel approaches, such as targeted therapies and immunotherapies, are being investigated alongside traditional antimitotic treatments to create more personalized and effective cancer care strategies. The ongoing development in this field highlights the importance of understanding not only how antimitotic drugs work but also how they can be optimized to provide the best possible outcomes for patients.In conclusion, the role of antimitotic agents in cancer treatment is a vital area of study within medical science. Their ability to inhibit cell division offers a powerful tool against the relentless growth of cancer cells. As research advances, the hope is to refine these treatments to maximize their effectiveness while reducing side effects, ultimately improving the quality of life for those battling cancer. The journey of understanding and utilizing antimitotic agents is a testament to the ongoing fight against one of humanity's most challenging diseases.

在医学和生物学领域，术语antimitotic指的是一类抑制或干扰有丝分裂过程的物质，该过程是细胞分裂成两个子细胞的过程。antimitotic药物的重要性不容小觑，尤其是在癌症治疗的背景下。癌细胞通常表现出不受控制的生长和分裂，导致肿瘤形成。因此，使用antimitotic药物可以成为减缓或阻止这些恶性细胞增殖的关键策略。最著名的antimitotic药物类别之一包括紫杉烷类，如紫杉醇和多西紫杉醇。这些药物通过稳定微管来发挥作用，这些微管是细胞分裂过程中染色体分离所必需的结构。通过防止这些微管的正常分解，antimitotic药物有效地停止了细胞周期，迫使癌细胞保持在非分裂状态。这种机制在治疗乳腺癌、肺癌和卵巢癌等多种癌症中尤其有用。另一类重要的antimitotic药物是长春花碱类，包括长春新碱和长春碱。与紫杉烷不同，长春花碱类药物抑制微管的组装，干扰形成细胞分裂所必需的有丝分裂纺锤体。这种干扰导致细胞死亡，特别是在快速分裂的细胞中，这是许多癌肿瘤的特征。antimitotic药物的有效性使其成为化疗方案中的基础，通常与其他治疗药物联合使用以增强疗效。虽然antimitotic药物的好处显而易见，但考虑其副作用也很重要。由于这些药物针对快速分裂的细胞，它们也可能影响那些频繁进行细胞分裂的健康组织，例如骨髓、胃肠道和毛囊中的细胞。这可能导致常见的副作用，如恶心、呕吐、脱发以及由于白细胞计数降低而增加感染风险。了解这些副作用对于医疗提供者在治疗期间有效管理患者护理至关重要。研究继续探索新的antimitotic药物和组合，以改善结果，同时最小化不良反应。新的方法，如靶向治疗和免疫治疗，正在与传统的antimitotic治疗一起研究，以创建更个性化和有效的癌症护理策略。该领域的持续发展突显了理解antimitotic药物的工作原理以及如何优化它们以提供最佳结果的重要性。总之，antimitotic药物在癌症治疗中的作用是医学科学中一个至关重要的研究领域。它们抑制细胞分裂的能力为对抗癌细胞无情生长提供了一种强有力的工具。随着研究的进展，希望能够完善这些治疗，以最大化其有效性，同时减少副作用，最终改善癌症患者的生活质量。理解和利用antimitotic药物的历程证明了人类与这一最具挑战性疾病之一之间的持续斗争。