pethidine hydrochloride

简明释义

盐酸哌替啶

英英释义

例句

1.During labor, many women receive pethidine hydrochloride to help alleviate their discomfort.

在分娩过程中，许多女性会接受哌替啶盐酸盐以缓解不适。

2.The doctor prescribed pethidine hydrochloride for the patient's severe pain management.

医生为患者的严重疼痛管理开了哌替啶盐酸盐。

3.The nurse prepared a dosage of pethidine hydrochloride for the post-operative patient.

护士为术后患者准备了一剂哌替啶盐酸盐。

4.Patients should be monitored closely when receiving pethidine hydrochloride due to its potential side effects.

由于可能的副作用，接受哌替啶盐酸盐的患者应密切监测。

5.In emergency situations, pethidine hydrochloride can be administered quickly to provide relief.

在紧急情况下，可以迅速给予哌替啶盐酸盐以提供缓解。

作文

Pethidine hydrochloride, often referred to simply as pethidine, is a potent opioid analgesic that has been widely used in medical practice for the management of moderate to severe pain. It is particularly effective in acute pain situations, such as postoperative pain or during labor. The drug works by binding to the mu-opioid receptors in the brain, which helps to inhibit the transmission of pain signals and alters the perception of pain. This makes it an important medication in both emergency and surgical settings.One of the key advantages of pethidine hydrochloride (哌替啶盐酸盐) is its rapid onset of action. When administered intravenously, patients can experience relief from pain within minutes. This quick response is crucial in situations where immediate pain relief is necessary. However, it is important to note that while pethidine hydrochloride (哌替啶盐酸盐) is effective for short-term pain management, it is not typically recommended for long-term use due to the potential for dependency and side effects associated with opioids.Additionally, pethidine hydrochloride (哌替啶盐酸盐) has a relatively short duration of action compared to other opioids, which means that patients may require repeated doses to maintain pain control. This characteristic can be beneficial in a clinical setting where quick adjustments to pain management are necessary. However, healthcare providers must carefully monitor patients for signs of adverse effects, which can include respiratory depression, sedation, and gastrointestinal disturbances.Another consideration when using pethidine hydrochloride (哌替啶盐酸盐) is its unique metabolite, norpethidine. Norpethidine can accumulate in the body, especially in patients with renal impairment, and may lead to neurotoxic effects such as seizures. Therefore, it is essential for clinicians to assess kidney function before prescribing this medication and to consider alternative analgesics when appropriate.In terms of its clinical applications, pethidine hydrochloride (哌替啶盐酸盐) is often used in obstetrics for pain relief during childbirth. Its ability to provide effective analgesia with fewer side effects on the fetus compared to other opioids makes it a preferred choice among many practitioners. However, the use of pethidine hydrochloride (哌替啶盐酸盐) in this context should be approached with caution, as it can still affect maternal and neonatal outcomes.Despite its benefits, the use of pethidine hydrochloride (哌替啶盐酸盐) has declined in recent years, largely due to the increasing awareness of the risks associated with opioid medications and the emergence of alternative analgesics that may have a better safety profile. As the medical community continues to seek safer and more effective pain management strategies, the role of pethidine hydrochloride (哌替啶盐酸盐) will likely evolve.In conclusion, pethidine hydrochloride (哌替啶盐酸盐) remains an important tool in the management of acute pain, particularly in surgical and obstetric settings. While it offers rapid pain relief, healthcare providers must remain vigilant about its potential side effects and the risk of dependency. Ongoing education about the safe use of opioids is essential for all healthcare professionals to ensure that patients receive optimal pain management while minimizing risks. As we advance our understanding of pain management, the role of pethidine hydrochloride (哌替啶盐酸盐) will continue to be evaluated in the context of patient safety and efficacy.

哌替啶盐酸盐（pethidine hydrochloride），通常简称为哌替啶，是一种强效的阿片类镇痛药，广泛用于医学实践中以管理中度至重度疼痛。它在急性疼痛情况下特别有效，例如术后疼痛或分娩期间。该药物通过与大脑中的μ-阿片受体结合，帮助抑制疼痛信号的传递并改变对疼痛的感知。这使其在急救和外科设置中成为重要的药物。pethidine hydrochloride（哌替啶盐酸盐）的一个主要优点是其快速起效。当静脉给药时，患者可以在几分钟内体验到疼痛缓解。这种快速反应在需要立即缓解疼痛的情况下至关重要。然而，值得注意的是，尽管pethidine hydrochloride（哌替啶盐酸盐）在短期疼痛管理中有效，但由于阿片类药物可能导致依赖和副作用，通常不建议长期使用。此外，pethidine hydrochloride（哌替啶盐酸盐）的作用持续时间相对较短，这意味着患者可能需要重复剂量以维持疼痛控制。这一特性在临床环境中是有利的，因为在这种情况下需要迅速调整疼痛管理。然而，医疗提供者必须仔细监测患者是否出现不良反应的迹象，这些不良反应可能包括呼吸抑制、镇静和胃肠道不适。使用pethidine hydrochloride（哌替啶盐酸盐）时另一个考虑因素是其独特的代谢产物去哌替啶（norpethidine）。去哌替啶可以在体内积累，尤其是在肾功能不全的患者中，可能导致神经毒性效应，例如癫痫发作。因此，临床医生在开处方之前评估肾功能至关重要，并在适当时考虑替代镇痛药。在其临床应用方面，pethidine hydrochloride（哌替啶盐酸盐）常用于产科，以缓解分娩期间的疼痛。与其他阿片类药物相比，它能够有效提供镇痛，并且对胎儿的副作用较少，使其成为许多从业者的首选。然而，在这种情况下使用pethidine hydrochloride（哌替啶盐酸盐）应谨慎，因为它仍可能影响母婴结局。尽管有其好处，近年来对pethidine hydrochloride（哌替啶盐酸盐）的使用有所减少，主要是因为人们越来越意识到与阿片类药物相关的风险，以及出现了安全性更好的替代镇痛药。随着医学界继续寻求更安全、更有效的疼痛管理策略，pethidine hydrochloride（哌替啶盐酸盐）的角色可能会发生变化。总之，pethidine hydrochloride（哌替啶盐酸盐）在急性疼痛管理中仍然是一种重要工具，特别是在外科和产科环境中。虽然它提供了快速的疼痛缓解，但医疗提供者必须对其潜在副作用和依赖风险保持警惕。关于安全使用阿片类药物的持续教育对于所有医疗专业人员至关重要，以确保患者在最大程度地减少风险的同时获得最佳的疼痛管理。随着我们对疼痛管理理解的深入，pethidine hydrochloride（哌替啶盐酸盐）的角色将在患者安全和疗效的背景下继续被评估。