sterically

简明释义

英[ˈsterɪkli]美[ˈsterɪkli]

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例句

1.During preparing the sterically hindered phenol ester, the method can simplify the catalyst neutralizing and removing course.

该方法在位阻苯酚酯的制备过程中，简化了催化剂中和及除去过程。

2.Sterically stabilized immunoliposome for brain targeting can bring drugs into brain directed by specific monoclonal antibody.

介绍了脑靶向空间稳定免疫脂质体制剂的研究进展。

3.Kodak company describe the use of a solvent - stabilizer system comprising a class of sterically hindered phenols acting both as coupler solvent and stabilizer.

柯达叙述了一类含有空间位阻酚类作为成色剂和稳定剂。

4.Kodak Company describe the use of a solvent-stabilizer system comprising a class of sterically hindered phenols acting both as coupler solvent and stabilizer.

柯达叙述了一类含有空间位阻酚类作为成色剂和稳定剂。

5.Kodak company describe the use of a solvent - stabilizer system comprising a class of sterically hindered phenols acting both as coupler solvent and stabilizer.

柯达叙述了一类含有空间位阻酚类作为成色剂和稳定剂。

6.Mass transfer mathematic model of carbon dioxide removal by sterically hindered amine has established.

建立了空间位阻胺脱碳的传质数学模型。

7.Synthesis of sterically hindered dicyclohexylmethyl, L menthyl and tert butyl diazoacetate by diazo transfer was described on this paper.

本文介绍了用重氮转移法合成具有较大空间位阻的重氮乙酸二环己基甲酯、L- 薄荷酯和叔丁酯。

8.According to the chelation of citric acid and the sterically hindered effect of glycol, the vesicle of rare earth mixture can been obtained.

依据柠檬酸的螯合作用和乙二醇的空间位阻效应，获得了稀土混合物囊泡。

9.The characteristics, protective principle and application of Sterically hindered silane blocking agents were reviewed.

综述了位阻型硅烷化试剂的特点、保护原理和应用。

10.Preparation and in vitro tumor cells selectivity of sterically stabilized immunoliposomal peptides in bee venom;

蜂毒多肽空间稳定免疫脂质体有较高的肿瘤细胞选择性。

11.The enzyme's active site is sterically designed to fit only specific substrates.

该酶的活性位点在立体上设计为仅适合特定底物。

12.The presence of sterically bulky substituents can affect the stability of the compound.

存在立体上庞大的取代基可能会影响化合物的稳定性。

13.Due to its sterically demanding structure, the compound is difficult to synthesize.

由于其立体上要求苛刻的结构，该化合物难以合成。

14.In this reaction, the sterically bulky groups prevent the approach of the reactants.

在这个反应中，立体上庞大的基团阻止了反应物的接近。

15.The molecule is sterically hindered, making it less reactive.

这个分子在立体上受到阻碍，使其反应性降低。

作文

In the realm of chemistry, the term sterically plays a crucial role in understanding molecular interactions and reactions. When we say that a molecule is sterically hindered, we refer to the spatial arrangement of atoms within that molecule, which can affect its reactivity and interactions with other molecules. For instance, larger groups attached to a central atom can create a barrier that prevents other molecules from approaching closely. This concept is vital in organic chemistry, particularly when discussing substitution reactions where the size of the substituents can determine the outcome of the reaction.Consider the example of a nucleophilic substitution reaction. If the nucleophile is attempting to attack a carbon atom that is surrounded by bulky groups, the reaction may proceed more slowly or not at all due to sterical hindrance. This phenomenon illustrates how the three-dimensional structure of a molecule can influence chemical behavior. In contrast, smaller substituents may allow for easier access to the reactive center, leading to faster reaction rates.Moreover, sterically controlled reactions are not limited to nucleophilic substitutions. They are also significant in enzyme catalysis, where the active site of an enzyme is designed to accommodate specific substrates. The sterical arrangement of amino acids in the active site can either facilitate or obstruct the binding of a substrate, thus affecting the enzyme's efficiency. Understanding these sterical effects allows chemists and biochemists to design better catalysts and improve reaction yields.In addition to its implications in chemistry, the concept of sterically hindered molecules has applications in materials science. For example, polymers with bulky side groups may exhibit different mechanical properties compared to those with smaller groups. The sterical arrangement of these groups can influence the flexibility, strength, and thermal stability of the material. Researchers can manipulate these properties by altering the sterical configuration of the polymer chains, leading to innovative materials with tailored characteristics.Furthermore, the importance of sterical considerations extends to the field of drug design. Many pharmaceutical compounds must navigate through biological membranes to reach their targets. A drug with a sterically bulky structure may struggle to penetrate cell membranes, whereas a smaller, less hindered molecule might pass through more easily. Thus, understanding the sterical properties of potential drug candidates is essential for optimizing their efficacy and bioavailability.In conclusion, the term sterically encompasses a wide range of implications across various scientific disciplines. Whether in chemistry, biochemistry, materials science, or pharmacology, the sterical arrangement of atoms and molecules significantly influences their behavior and interactions. By grasping the importance of sterically hindered structures, scientists can make informed decisions in their research and development efforts, ultimately leading to advancements in technology and medicine. The study of sterically related phenomena continues to be a vibrant area of inquiry, promising new discoveries and innovations in the years to come.

在化学领域，术语sterically在理解分子相互作用和反应中扮演着至关重要的角色。当我们说一个分子是sterically受阻时，我们指的是该分子内原子的空间排列，这会影响其反应性和与其他分子的相互作用。例如，附加到中心原子上的较大基团可能会形成一个屏障，阻止其他分子靠近。这一概念在有机化学中至关重要，特别是在讨论取代反应时，取代基的大小可以决定反应的结果。考虑一个亲核取代反应的例子。如果亲核试剂试图攻击一个被笨重基团包围的碳原子，反应可能会因sterical阻碍而进行得更慢，甚至根本无法进行。这一现象说明了分子的三维结构如何影响化学行为。相比之下，较小的取代基可能会使反应中心更容易接近，从而导致更快的反应速率。此外，sterically受控的反应不仅限于亲核取代反应。在酶催化中也很重要，酶的活性位点被设计为适应特定底物。活性位点中氨基酸的sterical排列能够促进或阻碍底物的结合，从而影响酶的效率。理解这些sterical效应使化学家和生物化学家能够设计更好的催化剂，提高反应产率。除了在化学中的意义之外，sterically受阻分子的概念在材料科学中也有应用。例如，具有笨重侧基的聚合物可能表现出与那些较小基团不同的机械性质。这些基团的sterical排列可以影响材料的柔韧性、强度和热稳定性。研究人员可以通过改变聚合物链的sterical构型来操控这些性质，从而导致具有定制特性的创新材料。此外，sterical考虑的重要性扩展到药物设计领域。许多药物化合物必须穿越生物膜以达到其靶标。具有sterically笨重结构的药物可能难以穿透细胞膜，而较小、受阻较少的分子则可能更容易通过。因此，理解潜在药物候选者的sterical特性对于优化其功效和生物利用度至关重要。总之，术语sterically涵盖了各个科学学科中的广泛影响。无论是在化学、生物化学、材料科学还是药理学中，原子和分子的sterical排列显著影响它们的行为和相互作用。通过掌握sterically受阻结构的重要性，科学家们可以在研究和开发工作中做出明智的决定，最终推动技术和医学的进步。对sterically相关现象的研究仍然是一个充满活力的探究领域，承诺在未来几年带来新的发现和创新。