neostigmine bromide

简明释义

溴化新斯的明

英英释义

例句

1.In emergency situations, neostigmine bromide can be used to reverse the effects of muscle relaxants.

在紧急情况下，可以使用新斯的明溴化物来逆转肌肉松弛剂的效果。

2.The nurse administered neostigmine bromide to improve muscle strength in the postoperative patient.

护士给术后患者注射了新斯的明溴化物以增强肌肉力量。

3.Patients receiving neostigmine bromide should be monitored for potential side effects like bradycardia.

接受新斯的明溴化物治疗的患者应监测可能出现的副作用，如心动过缓。

4.The doctor prescribed neostigmine bromide for the patient suffering from myasthenia gravis.

医生为患有重症肌无力的病人开了新斯的明溴化物。

5.Before surgery, the anesthesiologist discussed the use of neostigmine bromide for neuromuscular blockade reversal.

在手术前，麻醉师讨论了使用新斯的明溴化物来逆转神经肌肉阻滞。

作文

Neostigmine bromide is a medication that plays a crucial role in the treatment of various medical conditions, particularly in the field of neurology and anesthesiology. It is classified as an acetylcholinesterase inhibitor, which means it works by preventing the breakdown of acetylcholine, a neurotransmitter that is essential for communication between nerve cells and muscles. By inhibiting the enzyme acetylcholinesterase, neostigmine bromide increases the levels of acetylcholine in the body, thereby enhancing neuromuscular transmission. This property makes it particularly useful in the management of myasthenia gravis, a chronic autoimmune disorder characterized by weakness in the skeletal muscles. Patients with this condition often experience muscle fatigue and weakness, especially after periods of activity. The administration of neostigmine bromide can lead to significant improvements in muscle strength and endurance, allowing individuals to engage more effectively in their daily activities.In addition to its use in myasthenia gravis, neostigmine bromide is also utilized in the reversal of neuromuscular blockade following surgical procedures. During surgeries, anesthetics are often used to induce muscle relaxation, which is necessary for certain operations. However, once the procedure is complete, it is vital to reverse this muscle relaxation to restore normal function. Neostigmine bromide is administered to counteract the effects of neuromuscular blockers, enabling patients to regain control over their muscles and breathe independently. This application highlights the importance of neostigmine bromide not only in treating chronic conditions but also in acute medical settings.The pharmacological effects of neostigmine bromide are generally well-tolerated, but like any medication, it can have side effects. Common side effects include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. In some cases, patients may experience increased salivation or sweating due to the heightened levels of acetylcholine in the body. It is essential for healthcare providers to monitor patients closely when administering neostigmine bromide to manage any adverse reactions effectively. Additionally, the dosage must be tailored to each individual’s needs, as the response to the medication can vary significantly among patients.Overall, neostigmine bromide is a vital therapeutic agent that has transformed the management of neuromuscular disorders and has proven to be indispensable in surgical practice. Its ability to enhance neuromuscular transmission provides relief to patients suffering from debilitating conditions, improving their quality of life. Furthermore, its role in reversing neuromuscular blockade underscores its significance in ensuring patient safety during and after surgical interventions. As research continues to explore the full potential of neostigmine bromide, it remains a cornerstone in both clinical and surgical settings, highlighting the ongoing advancements in pharmacotherapy and patient care.

新斯的明溴化物是一种在治疗各种医疗条件中发挥重要作用的药物，特别是在神经学和麻醉学领域。它被归类为一种乙酰胆碱酯酶抑制剂，这意味着它通过防止乙酰胆碱这种神经递质的分解来发挥作用，乙酰胆碱对于神经细胞和肌肉之间的沟通至关重要。通过抑制乙酰胆碱酯酶这种酶，新斯的明溴化物增加了体内乙酰胆碱的水平，从而增强了神经肌肉传递。这一特性使其在重症肌无力的管理中尤为有用，这是一种以骨骼肌无力为特征的慢性自身免疫疾病。患有这种疾病的患者常常在活动后经历肌肉疲劳和无力。使用新斯的明溴化物可以显著改善肌肉力量和耐力，使个体能够更有效地参与日常活动。除了在重症肌无力中的应用外，新斯的明溴化物还用于逆转手术过程后的神经肌肉阻滞。在手术过程中，通常会使用麻醉剂来诱导肌肉放松，这对某些手术是必要的。然而，一旦手术完成，逆转这种肌肉放松以恢复正常功能是至关重要的。新斯的明溴化物被施用以抵消神经肌肉阻滞剂的效果，使患者能够重新控制自己的肌肉并独立呼吸。这一应用突显了新斯的明溴化物在治疗慢性病和急性医疗场景中的重要性。新斯的明溴化物的药理作用通常耐受良好，但与任何药物一样，它可能会有副作用。常见副作用包括胃肠道不适，如恶心、呕吐和腹泻。在某些情况下，患者可能会由于体内乙酰胆碱水平升高而出现唾液分泌或出汗增加。医疗提供者在施用新斯的明溴化物时必须密切监测患者，以有效管理任何不良反应。此外，剂量必须根据每个个体的需求进行调整，因为患者对药物的反应可能会有显著差异。总的来说，新斯的明溴化物是一种重要的治疗药物，它改变了神经肌肉疾病的管理，并且在外科实践中证明是不可或缺的。它增强神经肌肉传递的能力为遭受虚弱状况的患者提供了缓解，提高了他们的生活质量。此外，它在逆转神经肌肉阻滞中的作用突显了其在确保手术干预期间和之后患者安全方面的重要性。随着研究不断探索新斯的明溴化物的全部潜力，它仍然是临床和外科环境中的基石，突显了药物治疗和患者护理的持续进步。