mirror image isomer

简明释义

镜像异构体

英英释义

例句

1.The two compounds are mirror image isomers, which means they have the same molecular formula but differ in spatial arrangement.

这两种化合物是镜像异构体，这意味着它们具有相同的分子式，但在空间排列上有所不同。

2.When synthesizing drugs, it is crucial to identify the correct mirror image isomer to ensure safety and efficacy.

在合成药物时，识别正确的镜像异构体对于确保安全性和有效性至关重要。

3.Chemists often study mirror image isomers to understand their different properties and reactions.

化学家们经常研究镜像异构体以了解它们不同的性质和反应。

4.In pharmaceuticals, one mirror image isomer can be effective while the other may cause side effects.

在制药行业中，一个镜像异构体可能有效，而另一个可能会引起副作用。

5.The mirror image isomer of this molecule has been found to be more potent in inhibiting the enzyme.

这种分子的镜像异构体被发现对抑制酶更具效力。

作文

In the field of chemistry, the concept of chirality plays a crucial role in understanding molecular structures and their interactions. One of the most fascinating aspects of chirality is the existence of what we call mirror image isomers. These are pairs of molecules that are non-superimposable mirror images of each other, much like our left and right hands. While they may appear identical in structure, their spatial arrangements lead to significant differences in their chemical properties and biological activities.The study of mirror image isomers is particularly important in the pharmaceutical industry, where the efficacy and safety of drugs can be heavily influenced by their chirality. For instance, one enantiomer of a drug may have the desired therapeutic effect, while its mirror image counterpart could be inactive or even harmful. This phenomenon is exemplified by the case of thalidomide, a drug that was prescribed in the 1950s and 1960s. It was found that one enantiomer was effective as a sedative, while the other caused severe birth defects when taken by pregnant women. This tragic outcome underscores the importance of understanding mirror image isomers and their implications in drug design and development.To illustrate this concept further, let’s consider a simple example involving the amino acid alanine. Alanine exists in two forms: L-alanine and D-alanine, which are mirror image isomers of each other. These two forms have identical chemical formulas and similar physical properties, yet they behave differently in biological systems. L-alanine is naturally occurring and crucial for protein synthesis, while D-alanine is less common and has different roles in certain bacterial cell walls. This distinction highlights how mirror image isomers can have vastly different functions despite their structural similarities.Moreover, the presence of mirror image isomers also poses challenges in analytical chemistry. Techniques such as chromatography and spectroscopy must be carefully employed to differentiate between these isomers, as traditional methods may not provide the necessary resolution. Scientists often utilize chiral chromatography, which exploits the differences in interaction between the isomers and a chiral stationary phase, allowing for their separation and analysis.In conclusion, the study of mirror image isomers is essential for advancing our understanding of molecular chemistry and its applications. From drug development to biochemical processes, recognizing the significance of chirality and the differences between these isomers can lead to safer and more effective outcomes in various fields. As research continues to evolve, the exploration of mirror image isomers will undoubtedly yield new insights and innovations that enhance our comprehension of the molecular world around us.

在化学领域，手性概念在理解分子结构及其相互作用中起着至关重要的作用。手性的一个最迷人的方面是我们所称的镜像异构体的存在。这些是非重叠的分子对，是彼此的镜像，就像我们的左手和右手一样。虽然它们在结构上看起来相同，但它们的空间排列导致了显著的化学性质和生物活性差异。镜像异构体的研究在制药行业尤为重要，因为药物的有效性和安全性可能会受到手性的重大影响。例如，某种药物的一个对映体可能具有所需的治疗效果，而其镜像对应物可能无效甚至有害。这一现象以沙利度胺的案例为例，该药物在20世纪50年代和60年代被开处方。人们发现，一个对映体作为镇静剂有效，而另一个则在怀孕妇女服用时导致严重的出生缺陷。这一悲惨的结果强调了理解镜像异构体及其在药物设计和开发中的影响的重要性。为了进一步说明这一概念，让我们考虑一个简单的例子，涉及氨基酸丙氨酸。丙氨酸存在两种形式：L-丙氨酸和D-丙氨酸，它们是彼此的镜像异构体。这两种形式具有相同的化学式和相似的物理性质，但在生物系统中表现出不同的行为。L-丙氨酸是自然存在的，对蛋白质合成至关重要，而D-丙氨酸则较少见，并在某些细菌细胞壁中具有不同的作用。这一区别突显了尽管结构相似，镜像异构体可以具有截然不同的功能。此外，镜像异构体的存在也给分析化学带来了挑战。色谱法和光谱法等技术必须小心使用，以区分这些异构体，因为传统方法可能无法提供必要的分辨率。科学家们通常利用手性色谱法，利用异构体与手性固定相之间的相互作用差异，从而实现分离和分析。总之，研究镜像异构体对于推进我们对分子化学及其应用的理解至关重要。从药物开发到生化过程，认识到手性和这些异构体之间差异的重要性，可以在各个领域带来更安全、更有效的结果。随着研究的不断发展，探索镜像异构体无疑将产生新的见解和创新，增强我们对周围分子世界的理解。