maximum permissible dose

简明释义

最大允许剂量

英英释义

例句

1.In clinical trials, researchers must ensure that participants do not exceed the maximum permissible dose to avoid adverse effects.

在临床试验中，研究人员必须确保参与者不超过最大允许剂量以避免不良反应。

2.The safety guidelines state that the maximum permissible dose for children is lower than that for adults.

安全指南规定儿童的最大允许剂量低于成人的。

3.The doctor explained that the maximum permissible dose of this medication is 500 mg per day.

医生解释说这种药物的最大允许剂量是每天500毫克。

4.Before starting the treatment, it's crucial to understand the maximum permissible dose to prevent toxicity.

在开始治疗之前，了解最大允许剂量以防止毒性至关重要。

5.Pharmacists are trained to calculate the maximum permissible dose based on a patient's weight and age.

药剂师接受过培训，可以根据患者的体重和年龄计算出最大允许剂量。

作文

In the field of medicine and health, understanding the concept of maximum permissible dose is crucial for ensuring patient safety. The term refers to the highest amount of a substance, such as a medication or radiation, that an individual can be exposed to without experiencing harmful effects. This concept is particularly important in pharmacology, radiology, and toxicology, where the balance between efficacy and safety must be carefully managed. When a new drug is developed, researchers conduct extensive studies to determine its therapeutic effects and potential side effects. During these studies, they establish the maximum permissible dose to ensure that patients receive enough of the drug to achieve the desired outcome while minimizing the risk of adverse reactions. For instance, if a medication is effective at a certain dosage but causes severe side effects at higher doses, the maximum permissible dose will be set at the level where the benefits outweigh the risks.In radiology, the concept of maximum permissible dose is applied to protect patients from excessive exposure to radiation during diagnostic procedures, such as X-rays or CT scans. Medical professionals follow strict guidelines to limit the amount of radiation a patient receives, ensuring that it remains within the maximum permissible dose. This is vital not only for immediate safety but also for reducing the long-term risk of developing radiation-induced conditions, such as cancer.Furthermore, the maximum permissible dose is not static; it can change based on ongoing research and advancements in medical science. Regulatory agencies, such as the Food and Drug Administration (FDA) and the International Atomic Energy Agency (IAEA), continuously monitor and update guidelines to reflect new findings. As our understanding of human biology and the effects of various substances improves, the maximum permissible dose may be adjusted to enhance safety protocols.Additionally, the maximum permissible dose can vary depending on individual factors, including age, weight, and overall health. For example, children may have a lower maximum permissible dose for certain medications compared to adults due to their developing bodies and different metabolic rates. This variability necessitates personalized medicine approaches, where healthcare providers consider individual characteristics when determining the appropriate dosage for each patient.In conclusion, the maximum permissible dose is a fundamental concept in healthcare that plays a vital role in protecting patients from harm while allowing for effective treatment. It requires careful consideration and ongoing research to define safe exposure levels for various substances. By adhering to established maximum permissible doses, healthcare professionals can ensure that they provide the best possible care, balancing the need for effective treatment with the imperative of patient safety.

在医学和健康领域，理解最大允许剂量的概念对于确保患者安全至关重要。该术语指的是个体可以接触到的物质（如药物或辐射）而不会产生有害影响的最高量。这个概念在药理学、放射学和毒理学中尤为重要，在这些领域中，必须仔细管理疗效和安全性之间的平衡。当一种新药物被开发出来时，研究人员会进行广泛的研究，以确定其治疗效果和潜在副作用。在这些研究中，他们建立了最大允许剂量，以确保患者接受足够的药物以达到预期效果，同时将不良反应的风险降到最低。例如，如果一种药物在某一剂量下有效，但在更高剂量下会导致严重副作用，则最大允许剂量将设定在益处大于风险的水平。在放射学中，最大允许剂量的概念被应用于保护患者在诊断程序（如X光或CT扫描）中免受过度辐射的影响。医疗专业人员遵循严格的指导方针，以限制患者接收的辐射量，确保其保持在最大允许剂量之内。这不仅对即时安全至关重要，而且对减少长期发展辐射诱发疾病（如癌症）的风险也至关重要。此外，最大允许剂量并不是静态的；它可能会根据持续的研究和医学科学的进展而变化。监管机构，如食品和药物管理局（FDA）和国际原子能机构（IAEA），不断监测和更新指南，以反映新的发现。随着我们对人类生物学和各种物质影响的理解的提高，最大允许剂量可能会调整以增强安全协议。此外，最大允许剂量可能因个体因素而异，包括年龄、体重和整体健康状况。例如，与成人相比，儿童对某些药物的最大允许剂量可能较低，因为他们的身体正在发育，代谢率不同。这种变异性需要个性化医学的方法，医疗提供者在确定每位患者的适当剂量时考虑个体特征。总之，最大允许剂量是医疗保健中的一个基本概念，在保护患者免受伤害的同时允许有效治疗方面发挥着至关重要的作用。它需要仔细考虑和持续研究，以定义各种物质的安全暴露水平。通过遵守既定的最大允许剂量，医疗专业人员可以确保提供最佳护理，在有效治疗的需求与患者安全的必要性之间取得平衡。