levo form

简明释义

左旋体

英英释义

例句

1.Pharmaceutical companies often produce both the levo form (左旋形式) and the racemic mixture.

制药公司通常生产levo form（左旋形式）和外消旋混合物两种。

2.The study focused on the efficacy of the levo form (左旋形式) in treating the condition.

这项研究专注于levo form（左旋形式）在治疗该病症中的有效性。

3.Patients often receive the levo form (左旋形式) of the medication to minimize side effects.

患者通常会接受药物的levo form（左旋形式），以减少副作用。

4.The chemist explained that the drug was available in both its levo form (左旋形式) and its dextro form.

化学家解释说，这种药物有其levo form（左旋形式）和右旋形式两种。

5.In the lab, we need to separate the levo form (左旋形式) of the compound for our experiments.

在实验室里，我们需要分离该化合物的levo form（左旋形式）以供实验使用。

作文

The term levo form refers to a specific stereoisomer of a compound that rotates plane-polarized light to the left. This term is derived from the Latin word 'laevus,' meaning 'left.' Understanding the concept of levo form is essential in fields such as chemistry and pharmacology, as the properties and effects of molecules can vary significantly based on their stereochemistry. In organic chemistry, many molecules exist in multiple forms called stereoisomers. These isomers have the same molecular formula but differ in the spatial arrangement of their atoms. Among these, the levo form is particularly important because it can exhibit different biological activities compared to its counterpart, known as the 'dextro form,' which rotates light to the right. For instance, consider the case of amino acids, which are the building blocks of proteins. Most amino acids exist in both levo form and dextro form. In nature, almost all amino acids found in proteins are in the levo form. This preference for the levo form is crucial for the proper functioning of biological systems. If a protein were to incorporate a dextro amino acid instead of a levo one, it might not fold correctly, leading to malfunctioning proteins and potentially harmful consequences for the organism. Moreover, the significance of levo form extends beyond amino acids. Many drugs are chiral, meaning they have levo and dextro forms. The effectiveness and safety of a drug can depend heavily on its stereochemistry. For example, the drug thalidomide was sold as a sedative in the 1950s and 1960s, but it was later discovered that while one enantiomer (the levo form) was effective against morning sickness, the other (the dextro form) caused severe birth defects. This tragedy led to stricter regulations regarding drug testing and the necessity of understanding the implications of levo form in pharmaceutical development. In conclusion, the concept of levo form is not just a technical term in chemistry; it has profound implications for biology and medicine. The distinction between levo form and its counterpart can determine the efficacy of drugs, the structure of proteins, and the overall health of living organisms. As we continue to explore the complexities of molecular interactions, the importance of understanding terms like levo form becomes increasingly clear. It is vital for scientists, healthcare professionals, and students alike to grasp these concepts to advance our knowledge and improve human health.

术语levo form指的是一种特定的立体异构体，它使平面偏振光向左旋转。这个术语源自拉丁语单词'laevus'，意为'左'。理解levo form的概念在化学和药理学等领域至关重要，因为分子的性质和效果可能因其立体化学而显著不同。在有机化学中，许多分子以多种形式存在，称为立体异构体。这些异构体具有相同的分子式，但原子的空间排列不同。在这些异构体中，levo form尤其重要，因为它可能表现出与其对应物，即称为'dextro form'的异构体不同的生物活性，后者使光向右旋转。例如，考虑氨基酸的情况，氨基酸是蛋白质的构建块。大多数氨基酸都以levo form和dextro form两种形式存在。在自然界中，几乎所有在蛋白质中发现的氨基酸都是levo form。这种对levo form的偏好对生物系统的正常功能至关重要。如果一个蛋白质将一个dextro氨基酸而不是levo氨基酸纳入其中，它可能无法正确折叠，从而导致蛋白质功能失常，对生物体产生潜在的有害后果。此外，levo form的重要性不仅限于氨基酸。许多药物是手性分子，这意味着它们具有levo和dextro形式。药物的有效性和安全性可能在很大程度上依赖于其立体化学。例如，药物沙利度胺在20世纪50年代和60年代作为镇静剂出售，但后来发现，尽管一种对映体（levo form）在对抗晨吐方面有效，但另一种（dextro form）却导致严重的出生缺陷。这场悲剧导致了对药物测试的更严格监管，以及对理解levo form在药物开发中的影响的必要性。总之，levo form的概念不仅仅是化学中的一个技术术语；它对生物学和医学具有深远的影响。levo form与其对应物之间的区别可以决定药物的有效性、蛋白质的结构以及生物体的整体健康。随着我们继续探索分子相互作用的复杂性，理解像levo form这样的术语的重要性变得越来越明显。科学家、医疗专业人员和学生都必须掌握这些概念，以推动我们的知识进步并改善人类健康。