isotope dilution mass spectrometry

简明释义

同位素稀释质谱法

英英释义

例句

1.In clinical laboratories, isotope dilution mass spectrometry helps in the diagnosis of metabolic disorders.

在临床实验室中，同位素稀释质谱法有助于代谢疾病的诊断。

2.Researchers employed isotope dilution mass spectrometry to accurately quantify the concentration of heavy metals in soil.

研究人员采用同位素稀释质谱法准确量化土壤中重金属的浓度。

3.In environmental studies, isotope dilution mass spectrometry is used to measure trace elements in water samples.

在环境研究中，同位素稀释质谱法用于测量水样中的微量元素。

4.The pharmaceutical industry utilizes isotope dilution mass spectrometry for drug metabolism studies.

制药行业利用同位素稀释质谱法进行药物代谢研究。

5.By using isotope dilution mass spectrometry, scientists can determine the isotopic composition of various elements in geological samples.

通过使用同位素稀释质谱法，科学家能够确定地质样品中各种元素的同位素组成。

作文

In the realm of analytical chemistry, various techniques are employed to measure the concentration of elements and compounds in a sample. One such advanced method is isotope dilution mass spectrometry, which has gained significant attention for its accuracy and precision in quantifying trace elements. This technique utilizes isotopes, which are variants of chemical elements that have the same number of protons but different numbers of neutrons. By incorporating a known quantity of an isotopically enriched standard into a sample, scientists can effectively determine the concentration of the target analyte.The process begins with the addition of a stable or radioactive isotope of the element of interest to the sample. This isotope serves as a reference point, allowing for the dilution of the original sample's isotopic composition. After the sample is prepared, it is introduced into a mass spectrometer, an instrument that measures the mass-to-charge ratio of ions. The mass spectrometer separates the ions based on their mass, providing a spectrum that reflects the abundance of each isotope present in the sample.One of the primary advantages of isotope dilution mass spectrometry is its ability to provide highly accurate and precise measurements, even at low concentrations. Traditional methods may struggle with detecting trace amounts of elements, but this technique overcomes those challenges by using isotopes as markers. Furthermore, it minimizes potential errors associated with sample preparation and matrix effects, making it a reliable choice for various applications.This method is particularly beneficial in fields such as environmental monitoring, food safety, and clinical diagnostics. For instance, in environmental studies, researchers can use isotope dilution mass spectrometry to track heavy metal contamination in soil and water samples. Similarly, in food safety, it can be employed to detect harmful substances or verify the authenticity of products. In clinical settings, this technique aids in the analysis of biological fluids, helping to diagnose diseases or monitor therapeutic drug levels.Despite its advantages, isotope dilution mass spectrometry also has some limitations. The requirement for isotopically enriched standards can be a drawback, as these materials may not always be readily available. Additionally, the complexity of the instrumentation and the need for skilled personnel to operate the mass spectrometer can pose challenges for some laboratories.In conclusion, isotope dilution mass spectrometry is a powerful analytical tool that offers unparalleled accuracy and precision in measuring trace elements. Its application across various fields underscores its importance in scientific research and industry. As technology continues to advance, it is likely that this technique will become even more accessible and widely used, paving the way for new discoveries and innovations in analytical chemistry.

在分析化学领域，各种技术被用于测量样品中元素和化合物的浓度。其中一种先进的方法是同位素稀释质谱法，因其在定量微量元素方面的准确性和精确性而受到广泛关注。这种技术利用同位素，即具有相同质子数但中子数不同的化学元素变体。通过将已知量的富同位素标准物质加入样品中，科学家们可以有效地确定目标分析物的浓度。该过程始于向样品中添加感兴趣元素的稳定或放射性同位素。这个同位素作为参考点，使得原始样品的同位素组成能够被稀释。样品准备好后，将其引入质谱仪，这是一种测量离子的质荷比的仪器。质谱仪根据离子的质量分离它们，提供一个反映样品中每种同位素丰度的光谱。同位素稀释质谱法的主要优点之一是其能够提供高度准确和精确的测量，即使在低浓度下也能如此。传统方法可能难以检测微量元素，但这种技术通过使用同位素作为标记克服了这些挑战。此外，它减少了与样品制备和基质效应相关的潜在误差，使其成为各种应用的可靠选择。这种方法在环境监测、食品安全和临床诊断等领域特别有益。例如，在环境研究中，研究人员可以使用同位素稀释质谱法跟踪土壤和水样中的重金属污染。同样，在食品安全中，它可以用于检测有害物质或验证产品的真实性。在临床环境中，这项技术有助于分析生物液体，帮助诊断疾病或监测治疗药物水平。尽管有其优点，同位素稀释质谱法也有一些局限性。对富同位素标准的需求可能是一个缺点，因为这些材料并不总是容易获得。此外，仪器的复杂性以及需要熟练人员操作质谱仪可能会给某些实验室带来挑战。总之，同位素稀释质谱法是一种强大的分析工具，提供了无与伦比的准确性和精确性来测量微量元素。它在各个领域的应用突显了其在科学研究和工业中的重要性。随着技术的不断进步，这一技术可能会变得更加普及和广泛使用，为分析化学的新发现和创新铺平道路。