isonicotinic acid hydrazide

简明释义

异烟肼

英英释义

例句

1.In the laboratory, we use isonicotinic acid hydrazide to study its potential neuroprotective properties.

在实验室中，我们使用异烟肼来研究其潜在的神经保护特性。

2.The pharmaceutical formulation contains isonicotinic acid hydrazide as one of its active ingredients.

该药物配方包含异烟肼作为其活性成分之一。

3.The synthesis of new derivatives often starts with isonicotinic acid hydrazide as a precursor.

新衍生物的合成通常以异烟肼作为前体。

4.The compound isonicotinic acid hydrazide is commonly used in the synthesis of anti-tuberculosis drugs.

化合物异烟肼常用于抗结核药物的合成。

5.Researchers are investigating the effects of isonicotinic acid hydrazide on cancer cell lines.

研究人员正在调查异烟肼对癌细胞系的影响。

作文

Isonicotinic acid hydrazide, commonly known as INH, is a chemical compound that has gained significant importance in the field of medicine, particularly in the treatment of tuberculosis. This compound is a derivative of isonicotinic acid and hydrazine, which are both organic compounds. The significance of isonicotinic acid hydrazide (异烟肼) lies in its ability to inhibit the growth of Mycobacterium tuberculosis, the bacterium responsible for tuberculosis. The discovery of isonicotinic acid hydrazide (异烟肼) dates back to the 1950s when it was first used as an antitubercular agent. Its mechanism of action involves the inhibition of mycolic acid synthesis, which is crucial for the integrity of the bacterial cell wall. By disrupting this process, isonicotinic acid hydrazide (异烟肼) effectively kills the bacteria and helps in the recovery of patients suffering from tuberculosis.One of the remarkable aspects of isonicotinic acid hydrazide (异烟肼) is its effectiveness even against drug-resistant strains of tuberculosis. This has made it a cornerstone in the treatment regimen for tuberculosis, especially in cases where patients do not respond to other medications. However, it is essential to note that while isonicotinic acid hydrazide (异烟肼) is highly effective, it can also lead to several side effects. Common side effects include liver toxicity, peripheral neuropathy, and allergic reactions. Therefore, it is crucial for healthcare providers to monitor patients closely during treatment.In addition to its role in treating tuberculosis, isonicotinic acid hydrazide (异烟肼) has also been studied for its potential use in other medical conditions. Research has indicated that it may have applications in treating certain types of cancer and as a neuroprotective agent. These findings highlight the versatility of isonicotinic acid hydrazide (异烟肼) and its potential to contribute to various therapeutic areas beyond tuberculosis.Moreover, understanding the chemistry behind isonicotinic acid hydrazide (异烟肼) is crucial for future developments in medicinal chemistry. Researchers continue to explore modifications to the compound to enhance its efficacy and reduce side effects. This ongoing research is vital as the global burden of tuberculosis remains a pressing public health issue, especially in developing countries.In conclusion, isonicotinic acid hydrazide (异烟肼) is more than just a chemical compound; it represents hope for millions of individuals affected by tuberculosis worldwide. Its discovery and subsequent use in medicine underscore the importance of chemical research in addressing global health challenges. As we continue to learn more about this compound, it is essential to appreciate both its benefits and risks, ensuring that it remains a valuable tool in the fight against tuberculosis and potentially other diseases in the future.

异烟肼，通常被称为INH，是一种化学化合物，在医学领域，特别是在结核病的治疗中，具有重要意义。这种化合物是异烟酸和肼的衍生物，这两者都是有机化合物。异烟肼在抑制结核分枝杆菌（引起结核病的细菌）生长方面的重要性不言而喻。异烟肼的发现可以追溯到20世纪50年代，当时它首次作为抗结核药物使用。它的作用机制涉及抑制酰基酸的合成，这对于细菌细胞壁的完整性至关重要。通过破坏这一过程，异烟肼有效地杀死细菌，帮助结核病患者恢复健康。异烟肼的一个显著特点是它对耐药性结核病菌株的有效性。这使得它成为结核病治疗方案中的基石，尤其是在患者对其他药物无反应的情况下。然而，需要注意的是，虽然异烟肼极为有效，但也可能导致一些副作用。常见的副作用包括肝毒性、周围神经病和过敏反应。因此，医疗提供者在治疗期间密切监测患者至关重要。除了在结核病治疗中的作用外，异烟肼还被研究用于其他医疗条件。研究表明，它可能在某些类型的癌症治疗和作为神经保护剂方面具有应用潜力。这些发现突显了异烟肼的多功能性及其在结核病以外的各种治疗领域的潜力。此外，理解异烟肼背后的化学原理对于未来的药物化学发展至关重要。研究人员继续探索对该化合物的修改，以增强其疗效并减少副作用。这项持续的研究至关重要，因为全球结核病负担仍然是一个紧迫的公共卫生问题，尤其是在发展中国家。总之，异烟肼不仅仅是一种化学化合物；它代表着全球数百万结核病患者的希望。它的发现和随后在医学中的使用强调了化学研究在应对全球健康挑战中的重要性。随着我们对该化合物的了解不断加深，重视其益处和风险至关重要，确保它在未来继续成为抗击结核病及其他疾病的宝贵工具。