imino base

简明释义

亚氨碱

英英释义

例句

1.The imino base (亚氨基碱基) was identified as a key component in the catalytic mechanism of the enzyme.

该imino base（亚氨基碱基）被确定为酶催化机制中的关键成分。

2.We observed that the presence of an imino base (亚氨基碱基) can enhance the binding affinity of the ligand.

我们观察到，存在imino base（亚氨基碱基）可以增强配体的结合亲和力。

3.The imino base (亚氨基碱基) plays a crucial role in the stability of the nucleic acid structure.

在核酸结构的稳定性中，imino base（亚氨基碱基）起着至关重要的作用。

4.The structure of the compound was determined to contain an imino base (亚氨基碱基) which contributes to its unique properties.

该化合物的结构被确定包含一个imino base（亚氨基碱基），这使其具有独特的性质。

5.In our research, we synthesized a new molecule featuring an imino base (亚氨基碱基) that shows potential for drug development.

在我们的研究中，我们合成了一种新分子，具有一个imino base（亚氨基碱基），显示出药物开发的潜力。

作文

In the vast world of biochemistry, the study of nucleic acids has revealed many fascinating components that play crucial roles in genetic information transfer. One such component is the imino base, which is an important structural feature found in certain nucleobases. To understand the significance of the imino base, we must first delve into the structure of nucleic acids and their building blocks, the nucleotides.Nucleotides consist of a sugar molecule, a phosphate group, and a nitrogenous base. The nitrogenous bases can be categorized into two groups: purines and pyrimidines. Purines, which include adenine and guanine, have a double-ring structure, while pyrimidines, such as cytosine, thymine, and uracil, have a single-ring structure. Within these nitrogenous bases, the presence of the imino base is particularly noteworthy because it contributes to the stability and functionality of the nucleic acids.The imino base refers specifically to a functional group derived from an amine. It can be found in tautomeric forms of certain bases, such as cytosine and thymine. In the case of cytosine, for instance, the imino base form is crucial for the proper pairing with guanine during DNA replication. This pairing is essential for maintaining the integrity of the genetic code, as any errors in base pairing can lead to mutations.Moreover, the imino base plays a significant role in the hydrogen bonding that occurs between complementary bases. The ability of the imino base to participate in hydrogen bonds enhances the specificity of base pairing, ensuring that adenine pairs with thymine (or uracil in RNA) and guanine pairs with cytosine. This specificity is vital for accurate DNA replication and transcription processes, which are fundamental to cellular function and heredity.In addition to its structural importance, the imino base also has implications in the field of genetics and molecular biology. Researchers have found that alterations in the tautomeric forms of nucleobases, including the imino base, can lead to mispairing during DNA synthesis. Such mispairings may result in point mutations, which can have profound effects on an organism's phenotype and can even contribute to the development of diseases such as cancer.Furthermore, understanding the behavior of the imino base has practical applications in drug design and therapeutics. By targeting the interactions facilitated by the imino base within nucleic acids, scientists can develop molecules that inhibit or enhance specific biological processes. This knowledge paves the way for innovative treatments that could potentially rectify genetic disorders or combat viral infections.In conclusion, the imino base serves as a critical element in the structure and function of nucleic acids. Its role in base pairing stability, hydrogen bonding, and genetic fidelity highlights its importance in biological systems. As research continues to uncover the complexities of molecular interactions, the imino base will undoubtedly remain a focal point for scientists seeking to unravel the mysteries of life at the molecular level.

在生物化学的广阔世界中，核酸的研究揭示了许多在遗传信息转移中发挥关键作用的迷人组成部分。其中一个组成部分是亚氨基碱基，它是某些核苷酸中发现的重要结构特征。要理解亚氨基碱基的重要性，我们必须首先深入了解核酸的结构及其构建块——核苷酸。核苷酸由一个糖分子、一个磷酸基团和一个氮碱基组成。氮碱基可以分为两类：嘌呤和嘧啶。嘌呤，包括腺嘌呤和鸟嘌呤，具有双环结构，而嘧啶，如胞嘧啶、胸腺嘧啶和尿嘧啶，则具有单环结构。在这些氮碱基中，亚氨基碱基的存在尤其引人注目，因为它有助于核酸的稳定性和功能性。亚氨基碱基专指源自胺的功能团。它可以在某些碱基的互变异构体中找到，例如胞嘧啶和胸腺嘧啶。例如，在胞嘧啶的情况下，亚氨基碱基形式对于在DNA复制过程中与鸟嘌呤的正确配对至关重要。这种配对对于维持遗传密码的完整性至关重要，因为任何碱基配对中的错误都可能导致突变。此外，亚氨基碱基在互补碱基之间发生的氢键中也起着重要作用。亚氨基碱基参与氢键的能力增强了碱基配对的特异性，确保腺嘌呤与胸腺嘧啶（或RNA中的尿嘧啶）配对，鸟嘌呤与胞嘧啶配对。这种特异性对于准确的DNA复制和转录过程至关重要，这些过程是细胞功能和遗传的基础。除了其结构重要性外，亚氨基碱基在遗传学和分子生物学领域也具有重要意义。研究人员发现，核苷酸的互变形式的改变，包括亚氨基碱基，可能导致DNA合成过程中的错误配对。这种错误配对可能导致点突变，而这对生物体的表型产生深远影响，甚至可能导致癌症等疾病的发展。此外，了解亚氨基碱基的行为在药物设计和治疗中也具有实际应用。通过靶向核酸中由亚氨基碱基促进的相互作用，科学家可以开发抑制或增强特定生物过程的分子。这一知识为创新治疗方法铺平了道路，这些方法可能能够纠正遗传疾病或对抗病毒感染。总之，亚氨基碱基在核酸的结构和功能中起着关键作用。它在碱基配对稳定性、氢键和遗传保真性方面的作用凸显了它在生物系统中的重要性。随着研究继续揭示分子相互作用的复杂性，亚氨基碱基无疑将继续成为科学家们寻求揭开生命奥秘的焦点。