diastereomers

简明释义

英[daɪəˈstɪəˌriːmə]美[daɪəˈstɪrəmər]

n. 构体；非对映体（diastereomer 的复数）

英英释义

单词用法

同义词

反义词

例句

1.Diastereomers of cinchonine and cinchonidine were fully separated both under isocratic and gradient elutions on the chiral monolithic column.

在等度及梯度洗脱条件下，非对映异构体辛可宁与辛可尼丁被完全分离。

2.A cinchonine imprinted chiral monolithic column was prepared for the separation of the diastereomers of cinchonine and cinchonidine by in situ molecular imprinting technique.

采用原位分子印迹技术，单步制备了一种辛可宁印迹的手性整体柱。

3.A cinchonine imprinted chiral monolithic column was prepared for the separation of the diastereomers of cinchonine and cinchonidine by in situ molecular imprinting technique.

采用原位分子印迹技术，单步制备了一种辛可宁印迹的手性整体柱。

4.Diastereomers that are not enantiomers also fall into this category.

不是对映异构体的非对映异构体也属于这一类。

5.The relative contents of diastereomers, 2r 4r and 2s 4r, in solution are influenced by both the solvents used and the characteristics and locations of substituents on 2-aryl.

芳基上取代基的位置和性质以及使用的溶剂都能够影响非对映体2r,4r和2s, 4r在溶液中的相对含量。

6.We applied dehydroabietyl chloride that is a new chiral reagent for the formation of diastereomers and resolved D, L-amino acid.

探索了新型胺类手性衍生试剂-脱氢松香酸酰氯与氨基酸的衍生反应。

7.The two compounds are not mirror images of each other, making them distereomers 非对映体.

这两种化合物不是彼此的镜像，因此它们是distereomers 非对映体。

8.The presence of distereomers 非对映体 in a mixture can complicate the separation process.

混合物中存在distereomers 非对映体可能会使分离过程变得复杂。

9.In organic chemistry, distereomers 非对映体 can have significantly different physical properties.

在有机化学中，distereomers 非对映体可能具有显著不同的物理性质。

10.The synthesis of distereomers 非对映体 often requires careful control of reaction conditions.

合成distereomers 非对映体通常需要仔细控制反应条件。

11.Researchers are studying the biological activity of various distereomers 非对映体 to understand their effects on human health.

研究人员正在研究各种distereomers 非对映体的生物活性，以了解它们对人类健康的影响。

作文

In the study of organic chemistry, understanding the concept of stereochemistry is crucial. One important aspect of stereochemistry is the existence of different types of isomers. Among these isomers, we find a specific category known as diastereomers. Diastereomers are defined as stereoisomers that are not related as mirror images. This means that while they have the same molecular formula and connectivity of atoms, their spatial arrangement differs in such a way that they cannot be superimposed on one another. To illustrate this concept, consider a simple example involving a compound with two chiral centers. When a molecule possesses two chiral centers, it can lead to multiple stereoisomers. In this case, there are four possible stereoisomers: two of them will be enantiomers (which are mirror images of each other), while the other two will be diastereomers. The diastereomers will differ in at least one configuration at one chiral center but will retain the same configuration at the other chiral center. The significance of diastereomers extends beyond mere classification. They often exhibit different physical and chemical properties, which can have practical implications in various fields, including pharmaceuticals. For instance, one diastereomer of a drug may be therapeutically active, while another may be inactive or even harmful. This difference arises because the spatial arrangement of atoms in diastereomers can affect how a molecule interacts with biological systems, such as enzymes and receptors. Moreover, the separation and identification of diastereomers can be essential in synthetic chemistry. Chemists often aim to isolate specific diastereomers to study their unique properties or to utilize them in reactions that require a particular stereochemical outcome. Techniques such as chromatography or crystallization can be employed to achieve this separation based on their differing physical properties.In conclusion, diastereomers play a vital role in the field of stereochemistry. Their distinct characteristics and behaviors underline the importance of stereochemistry in organic compounds. By grasping the concept of diastereomers, students and professionals alike can better appreciate the complexities of molecular interactions and the significance of chirality in chemical reactions. As research continues to advance, the understanding of diastereomers will undoubtedly contribute to the development of new materials and drugs, showcasing the profound impact of stereochemistry on science and technology.

在有机化学的研究中，理解立体化学的概念至关重要。立体化学的一个重要方面是不同类型异构体的存在。在这些异构体中，我们发现一个特定的类别称为diastereomers。Diastereomers被定义为非镜像关系的立体异构体。这意味着它们具有相同的分子式和原子的连接方式，但它们的空间排列以某种方式不同，因此无法重叠。为了说明这一概念，考虑一个具有两个手性中心的化合物的简单例子。当一个分子具有两个手性中心时，它可以导致多个立体异构体。在这种情况下，有四种可能的立体异构体：其中两个将是对映体（彼此的镜像），而其他两个将是diastereomers。Diastereomers在至少一个手性中心的构型上会有所不同，但在另一个手性中心上保持相同的构型。Diastereomers的重要性超出了单纯的分类。它们通常表现出不同的物理和化学性质，这在包括制药在内的各个领域都有实际意义。例如，一种药物的某个diastereomer可能具有治疗活性，而另一个可能无效甚至有害。这种差异的产生是因为diastereomers中原子的空间排列可能影响分子与生物系统（如酶和受体）的相互作用。此外，分离和识别diastereomers在合成化学中可能至关重要。化学家通常旨在分离特定的diastereomers以研究其独特的性质或在需要特定立体化学结果的反应中利用它们。可以使用色谱法或结晶法等技术，根据它们不同的物理性质实现这种分离。总之，diastereomers在立体化学领域中扮演着重要角色。它们独特的特征和行为突显了立体化学在有机化合物中的重要性。通过掌握diastereomers的概念，学生和专业人士可以更好地理解分子相互作用的复杂性以及手性在化学反应中的重要性。随着研究的不断进展，对diastereomers的理解无疑将有助于新材料和药物的发展，展示立体化学对科学和技术的深远影响。