pyknotic

简明释义

英[pɪkˈnɒtɪk]美[pɪkˈnɒtɪk]

adj. 致密的；固缩的

英英释义

单词用法

同义词

反义词

例句

1.The cytologic features of normal squamous epithelial cells can be seen at the center top and bottom, with orange to pale blue plate-like squamous cells that have small pyknotic nuclei.

图中上部及下部示正常鳞状上皮细胞特征，鳞状细胞呈红色、淡蓝色，核小而固缩。

2.RESULTS: The layer of CA1 pyramidal cells in both AO groups became thinner with pyknotic nuclei than control.

结果：与对照组相比，各氯化铝组均可见海马CA 1区细胞层变薄伴明显核固缩。

3.Many nuclei have become pyknotic (shrunken and dark) and have then undergone karorrhexis (fragmentation) and karyolysis (dissolution). The cytoplasm and cell borders are not recognizable.

许多细胞核发生了核浓缩，接着出现核碎裂和核溶解现象。

4.Many nuclei have become pyknotic (shrunken and dark) and have then undergone karorrhexis (fragmentation) and karyolysis (dissolution). The cytoplasm and cell borders are not recognizable.

许多细胞核发生了核浓缩，接着出现核碎裂和核溶解现象。

5.In histological studies, pyknotic 浓缩的 cells are often indicative of necrosis.

在组织学研究中，pyknotic 浓缩的细胞通常表明坏死。

6.The pathologist observed that the cells in the biopsy were markedly pyknotic 浓缩的, indicating possible cell death.

病理学家观察到活检中的细胞明显是pyknotic 浓缩的，这表明可能存在细胞死亡。

7.During the examination, the doctor noted that the pyknotic 浓缩的 nuclei were a sign of an advanced stage of the disease.

在检查过程中，医生注意到这些pyknotic 浓缩的细胞核是疾病晚期的迹象。

8.The presence of pyknotic 浓缩的 nuclei in the tissue sample raised concerns about the patient's prognosis.

组织样本中存在pyknotic 浓缩的细胞核引发了对患者预后的担忧。

9.Researchers found that the number of pyknotic 浓缩的 cells increased significantly after exposure to the toxin.

研究人员发现，暴露于毒素后，pyknotic 浓缩的细胞数量显著增加。

作文

In the study of biology, particularly in the field of cell biology, understanding the various stages of cell development and differentiation is crucial. One interesting term that often arises in this context is pyknotic, which refers to a specific stage of chromatin condensation during cell division. When cells prepare to divide, they undergo several changes, one of which is the condensation of chromatin into more compact structures. This process is essential for the proper segregation of genetic material into daughter cells.The term pyknotic itself comes from the Greek word 'pyknos', meaning dense or thick. In cellular biology, when we say that a nucleus is pyknotic, we are describing a nucleus that appears dense and darkly stained under a microscope due to the highly condensed chromatin. This appearance is characteristic of certain types of cells that are undergoing apoptosis, or programmed cell death. During apoptosis, the chromatin becomes increasingly compacted, leading to the formation of a pyknotic nucleus, which is often one of the hallmarks of this process.Understanding the significance of a pyknotic nucleus is important for researchers studying cell death and its implications in various diseases, including cancer. In many cancers, the regulation of apoptosis is disrupted, leading to uncontrolled cell growth. By studying the presence of pyknotic nuclei in tissue samples, pathologists can gain insights into the health of the tissue and the effectiveness of treatments aimed at inducing apoptosis in cancer cells.Moreover, the concept of pyknotic nuclei extends beyond cancer research. It is also relevant in the context of developmental biology, where the timing of cell death is crucial for proper organismal development. For example, during the formation of limbs in embryonic development, certain cells must undergo apoptosis to allow for the sculpting of fingers and toes. The identification of pyknotic nuclei in these developing tissues can provide valuable information about the normal progression of development.In conclusion, the term pyknotic encapsulates a vital aspect of cellular biology. It not only describes a specific morphological feature of cells undergoing apoptosis but also serves as a significant marker for understanding various biological processes, from cancer progression to normal development. As our knowledge of cell biology expands, the importance of terms like pyknotic will continue to grow, providing us with deeper insights into the complexities of life at the cellular level. Therefore, it is essential for students and professionals in the field to familiarize themselves with such terminology to enhance their understanding of cellular functions and the mechanisms underlying health and disease.

在生物学研究中，特别是在细胞生物学领域，理解细胞发育和分化的各个阶段至关重要。一个经常出现的有趣术语是pyknotic，它指的是细胞分裂过程中染色质浓缩的特定阶段。当细胞准备分裂时，它们会经历几个变化，其中之一是染色质凝聚成更紧凑的结构。这个过程对于将遗传物质正确分配到子细胞中是必不可少的。术语pyknotic本身来源于希腊词“pyknos”，意为密集或厚。在细胞生物学中，当我们说一个细胞核是pyknotic时，我们是在描述一个由于高浓缩的染色质在显微镜下呈现出密集和深色染色的细胞核。这种外观是某些类型细胞正在经历凋亡或程序性细胞死亡时的特征。在凋亡过程中，染色质变得越来越紧凑，导致形成pyknotic细胞核，这通常是这一过程的标志之一。理解pyknotic细胞核的意义对于研究细胞死亡及其在各种疾病中的影响的研究人员来说非常重要。在许多癌症中，凋亡的调节被破坏，导致细胞生长失控。通过研究组织样本中pyknotic细胞核的存在，病理学家可以深入了解组织的健康状况以及旨在诱导癌细胞凋亡的治疗效果。此外，pyknotic细胞核的概念超越了癌症研究。在发育生物学的背景下，细胞死亡的时机对正常生物体的发育至关重要。例如，在胚胎发育过程中，肢体形成期间，某些细胞必须经历凋亡，以允许手指和脚趾的雕刻。在这些发育组织中识别pyknotic细胞核可以提供有关正常发育进程的宝贵信息。总之，术语pyknotic概括了细胞生物学的一个重要方面。它不仅描述了经历凋亡的细胞的特定形态特征，而且作为理解各种生物过程的重要标志，从癌症进展到正常发育。随着我们对细胞生物学知识的扩展，像pyknotic这样的术语的重要性将继续增长，为我们提供对生命复杂性的更深入见解。因此，学生和专业人士在该领域熟悉这些术语对于增强他们对细胞功能及健康与疾病机制的理解至关重要。