denatured state

简明释义

变性状态

英英释义

A denatured state refers to a condition in which a protein or nucleic acid has lost its natural structure due to the disruption of non-covalent interactions, resulting in the loss of its biological function.

变性状态是指蛋白质或核酸因非共价相互作用的破坏而失去其自然结构的状态,从而导致其生物功能的丧失。

例句

1.The denatured state of DNA can be induced by heating it, leading to the separation of its strands.

通过加热可以诱导DNA的变性状态,导致其链的分离。

2.In the laboratory, scientists often use heat or chemicals to achieve a denatured state in proteins for analysis.

在实验室中,科学家通常使用热或化学物质使蛋白质达到变性状态以进行分析。

3.When exposed to high temperatures, enzymes can lose their functionality and enter a denatured state.

当暴露于高温时,酶会失去其功能并进入变性状态

4.In the process of cooking, proteins often undergo a transformation into a denatured state, which alters their texture and flavor.

在烹饪过程中,蛋白质通常会转变为变性状态,这会改变它们的质地和味道。

5.During pasteurization, milk proteins are partially converted to a denatured state to ensure safety.

在巴氏消毒过程中,牛奶中的蛋白质部分转变为变性状态以确保安全。

作文

The concept of a denatured state is crucial in various scientific fields, particularly in biochemistry and molecular biology. When we refer to a protein or a nucleic acid being in a denatured state, we are talking about a structural change that disrupts its normal function. Proteins, for example, are made up of long chains of amino acids that fold into specific three-dimensional shapes. These shapes are essential for their biological activity. However, when exposed to certain conditions such as extreme temperatures, pH changes, or the presence of certain chemicals, proteins can lose their native structure and enter a denatured state. This process is often irreversible and can lead to loss of function, which is why understanding it is vital in many applications.In cooking, for instance, the denaturation of proteins is a common phenomenon. When you cook an egg, the heat causes the proteins in the egg white to unfold and aggregate, resulting in the firm texture of a cooked egg. This transformation is a practical example of how a denatured state can be utilized for culinary purposes. Similarly, in the food industry, the process of pasteurization involves heating liquids to kill harmful bacteria, which also leads to the denaturation of proteins. Thus, the denatured state not only signifies a loss of biological function but can also be harnessed for beneficial outcomes.In the realm of molecular biology, the denatured state is particularly relevant during techniques such as polymerase chain reaction (PCR). In this process, DNA is subjected to high temperatures to separate its strands, leading to a denatured state. This allows for the amplification of specific DNA sequences, which is crucial for genetic research, forensic analysis, and medical diagnostics. Understanding how to manipulate the denatured state of DNA has opened up numerous possibilities in biotechnology and medicine.Moreover, the study of the denatured state extends beyond proteins and nucleic acids. It also applies to other macromolecules like polysaccharides and lipids. For example, the gelatinization of starch occurs when it is heated in water, causing it to transition into a denatured state where it thickens and becomes viscous. This property is exploited in various food products, demonstrating the versatility of the denatured state across different materials.In conclusion, the denatured state is a fundamental concept that illustrates the delicate balance between structure and function in biological macromolecules. Its implications reach far and wide, influencing areas from culinary arts to advanced scientific research. By understanding the conditions that lead to a denatured state and the consequences that follow, we can better appreciate the complexity of life at the molecular level and leverage this knowledge for practical applications. Whether in the kitchen or the laboratory, the principles of denaturation remind us of the intricate interplay between structure and function that defines living organisms.

‘变性状态’这个概念在多个科学领域中至关重要,尤其是在生物化学和分子生物学中。当我们提到蛋白质或核酸处于‘变性状态’时,我们指的是一种结构变化,这种变化会破坏其正常功能。例如,蛋白质是由长链氨基酸组成的,它们折叠成特定的三维形状。这些形状对它们的生物活性至关重要。然而,当暴露于某些条件下,例如极端温度、pH变化或某些化学物质的存在时,蛋白质可能会失去其天然结构并进入‘变性状态’。这一过程通常是不可逆的,并且可能导致功能丧失,这就是为什么理解它在许多应用中至关重要。例如,在烹饪中,蛋白质的变性是一种常见现象。当你煮鸡蛋时,热量使蛋白质在蛋清中展开并聚集,导致熟鸡蛋的坚硬纹理。这种转变是‘变性状态’如何被用于烹饪目的的一个实际例子。同样,在食品工业中,巴氏杀菌过程涉及将液体加热以杀死有害细菌,这也导致蛋白质的变性。因此,‘变性状态’不仅意味着生物功能的丧失,还可以被利用于有益的结果。在分子生物学领域,‘变性状态’在聚合酶链式反应(PCR)等技术中尤为相关。在这个过程中,DNA被置于高温环境中以分离其链,从而导致‘变性状态’。这使得特定DNA序列的扩增成为可能,这对基因研究、法医分析和医学诊断至关重要。理解如何操控DNA的‘变性状态’为生物技术和医学开辟了无数可能。此外,‘变性状态’的研究不仅适用于蛋白质和核酸,也适用于其他大分子,如多糖和脂质。例如,淀粉在水中加热时发生明胶化,导致其转变为一种‘变性状态’,使其变得浓稠且粘稠。这一特性在各种食品产品中得到了利用,展示了‘变性状态’在不同材料中的多样性。总之,‘变性状态’是一个基本概念,它说明了生物大分子中结构与功能之间的微妙平衡。其影响深远,涉及从烹饪艺术到先进科学研究的多个领域。通过理解导致‘变性状态’的条件及其后果,我们可以更好地欣赏分子水平上生命的复杂性,并利用这一知识进行实际应用。无论是在厨房还是实验室,变性原理提醒我们,定义生物体的结构与功能之间的复杂相互作用。

相关单词

denatured

denatured详解:怎么读、什么意思、用法