steric

简明释义

英[ˈsterɪk]美[ˈsterɪk]

adj. 位的（副词 sterically, 异体字 sterical）；（原子的）空间（排列）的

n. （Steric）人名；（瑞典）斯特里克

英英释义

单词用法

同义词

反义词

例句

1.This approach covers the substrate range of aliphatic, aromatic, heterocyclic and steric hindrance ketones.

该催化剂适用于各种脂肪酮、芳香酮、杂环酮和位阻酮。

2.It follow therefore that the steric blocking effects of substituents are reflected in adverse kinetic, rather than thermodynamic factors.

由此可以看出，取代基的主本阻碍反应，是反映在违背动力学因素而不是热力学因素。

3.The steric effects on the reaction of 6, 6-dialkylfulvene with organolithium have been studied.

本文研究了6，6-二烷基富烯与有机锂反应的立体效应。

4.SSD could acquire direct and steric image. Reconstruction methods of SCT could display more information of complicated spine fracture directly.

结论SCT重建是了解复杂性脊柱骨折的有效方法，几种SCT后处理方法相结合能更直观全面显示复杂脊柱骨折的具体情况。

5.Severe steric effects at the reactive carbon would impede the substitution.

大的立体效应阻止在碳上的取代。

6.Their extraction ability markedly decreases with the increase of the steric hindrance from ester alkyl group.

萃取能力随着酯烷基空间位阻的增大而显著降低。

7.A rather more complex case is that of steric isomerism.

更复杂的情形是立体异构问题。

8.It was considered that steric hindrance and electrostatic repulsion were the main stabilizing mechanism.

空间位阻和静电排斥是其乳状液稳定的主要机理。

9.The steric 空间的 hindrance in this reaction slows down the rate significantly.

这个反应中的空间的阻碍显著减缓了反应速率。

10.The steric 空间的 arrangement of atoms can affect the molecule's properties.

原子的空间的排列可以影响分子的性质。

11.The steric 空间的 bulkiness of the substituents influences the stability of the compound.

取代基的空间的庞大程度影响化合物的稳定性。

12.We need to consider the steric 空间的 effects when designing new catalysts.

在设计新催化剂时，我们需要考虑空间的效应。

13.In organic chemistry, steric 空间的 factors are crucial for understanding reaction mechanisms.

在有机化学中，空间的因素对于理解反应机制至关重要。

作文

The concept of steric hindrance is crucial in the field of chemistry, particularly when discussing molecular interactions and the behavior of different compounds. Steric effects arise from the spatial arrangement of atoms within a molecule and how they influence chemical reactions. When molecules approach each other, their electron clouds repel one another due to steric hindrance, which can significantly affect the rate and outcome of a reaction. For instance, larger substituents on a molecule can block access to reactive sites, making it difficult for reactants to collide effectively. This phenomenon is not only relevant in organic chemistry but also plays a pivotal role in biochemistry, particularly in enzyme-substrate interactions.In drug design, understanding steric effects is essential. Many drugs are designed to fit precisely into the active sites of enzymes, much like a key fits into a lock. If a drug has a steric bulk that is too large, it may not be able to bind effectively to its target, rendering it ineffective. Conversely, if the drug is too small, it may not interact strongly enough to elicit a biological response. Therefore, medicinal chemists must carefully consider the steric properties of potential drug candidates during the design process.Moreover, steric factors can also influence the stability of molecules. For example, in many cases, bulky groups can prevent the formation of certain conformations that would otherwise lead to instability or reactivity. This is particularly important in the study of reaction mechanisms, where the orientation of reactants can dictate the pathway and products of a reaction. By analyzing the steric effects at play, chemists can predict the likelihood of various outcomes and tailor their experiments accordingly.In addition to its applications in chemistry, the concept of steric hindrance can also be observed in everyday life. For example, consider the arrangement of furniture in a room. If two pieces of furniture are too large for the space, they may obstruct movement and make the area feel cramped. Similarly, in molecular terms, if atoms or groups within a molecule are too large, they can create unfavorable conditions for interactions with other molecules.Furthermore, the implications of steric effects extend into materials science as well. The properties of polymers, for instance, can be greatly influenced by the steric arrangement of their monomer units. Researchers often manipulate these steric factors to develop materials with specific characteristics, such as flexibility, strength, or thermal stability.In conclusion, the term steric encompasses a wide range of phenomena that are vital for understanding molecular interactions and designing effective compounds. From drug development to materials science, the effects of steric hindrance are omnipresent and must be taken into account to achieve desired results. As research continues to advance, a deeper comprehension of steric factors will undoubtedly lead to new innovations and breakthroughs in various scientific fields.

在化学领域，steric（立体的）阻碍的概念至关重要，尤其是在讨论分子相互作用和不同化合物的行为时。Steric（立体的）效应源于分子内部原子的空间排列以及它们如何影响化学反应。当分子彼此靠近时，由于steric（立体的）阻碍，它们的电子云相互排斥，这可能显著影响反应的速率和结果。例如，分子上的较大取代基可能会阻碍反应位点的接近，使得反应物难以有效碰撞。这种现象不仅与有机化学相关，还在生物化学中发挥着关键作用，尤其是在酶-底物相互作用中。在药物设计中，理解steric（立体的）效应是必不可少的。许多药物被设计为能够精确地适配酶的活性位点，就像钥匙插入锁一样。如果一种药物的steric（立体的）体积过大，它可能无法有效结合到其靶点，从而使其失去效力。相反，如果药物太小，它可能无法产生足够强的相互作用以引发生物反应。因此，药物化学家在设计潜在药物候选者时，必须仔细考虑其steric（立体的）特性。此外，steric（立体的）因素还会影响分子的稳定性。例如，在许多情况下，笨重的基团可能会阻止形成某些构象，而这些构象本可能导致不稳定或反应性。这在反应机制的研究中尤为重要，因为反应物的取向可以决定反应的途径和产物。通过分析所涉及的steric（立体的）效应，化学家可以预测各种结果的可能性，并相应地调整实验。除了在化学中的应用，steric（立体的）阻碍的概念也可以在日常生活中观察到。例如，考虑房间内家具的摆放。如果两件家具对空间来说太大，它们可能会妨碍移动并使区域感觉拥挤。同样，在分子术语中，如果分子内的原子或基团过大，它们可能会造成与其他分子相互作用的不利条件。此外，steric（立体的）效应的影响还扩展到材料科学领域。例如，聚合物的性质可以受到其单体单位的steric（立体的）排列的极大影响。研究人员通常操控这些steric（立体的）因素，以开发具有特定特性的材料，例如柔韧性、强度或热稳定性。总之，steric（立体的）这个术语涵盖了广泛的现象，对于理解分子相互作用和设计有效化合物至关重要。从药物开发到材料科学，steric（立体的）阻碍的效应无处不在，必须加以考虑以实现期望的结果。随着研究的不断推进，对steric（立体的）因素的更深入理解无疑将导致各个科学领域的新创新和突破。