cardiac glycoside

简明释义

强心苷

英英释义

例句

1.Digitalis is a well-known type of cardiac glycoside used in clinical practice.

地高辛是临床实践中一种著名的心脏糖苷。

2.The mechanism of action of cardiac glycoside involves increasing the force of heart contractions.

心脏糖苷的作用机制包括增强心脏收缩的力量。

3.The doctor prescribed a medication containing cardiac glycoside to help improve the patient's heart function.

医生开了一种含有心脏糖苷的药物，以帮助改善患者的心脏功能。

4.Monitoring potassium levels is crucial for patients on cardiac glycoside medications.

接受心脏糖苷药物治疗的患者，监测钾水平至关重要。

5.Patients with congestive heart failure may benefit from cardiac glycoside therapy.

患有充血性心力衰竭的患者可能会从心脏糖苷疗法中受益。

作文

The human body is a complex system that relies on various biochemical substances to maintain its functions. Among these substances, one particularly significant class is known as cardiac glycosides. These compounds are derived from plants and have been used for centuries in traditional medicine to treat heart conditions. The primary function of cardiac glycosides is to increase the force of heart contractions, making them essential in the management of heart failure and arrhythmias. This essay aims to explore the role, mechanism, and applications of cardiac glycosides in modern medicine.Historically, cardiac glycosides have been extracted from plants such as foxglove (Digitalis purpurea) and lily of the valley (Convallaria majalis). The most well-known cardiac glycoside is digoxin, which is commonly used in clinical practice. These compounds work by inhibiting the sodium-potassium ATPase pump in cardiac cells, leading to an increase in intracellular sodium levels. This, in turn, causes an influx of calcium ions, enhancing the contractility of the heart muscle. As a result, patients with weakened hearts can experience improved cardiac output, alleviating symptoms like shortness of breath and fatigue.In addition to their positive effects on heart contractions, cardiac glycosides also have a regulatory effect on heart rhythm. They are particularly useful in treating atrial fibrillation, a condition characterized by an irregular heartbeat. By slowing down the conduction through the atrioventricular (AV) node, cardiac glycosides help restore a more regular heart rhythm. However, the use of these compounds requires careful monitoring due to their narrow therapeutic window; excessive doses can lead to toxicity, causing symptoms such as nausea, vomiting, and even life-threatening arrhythmias.The applications of cardiac glycosides extend beyond heart failure and arrhythmias. Research has shown potential benefits in other areas, such as cancer treatment. Some studies suggest that cardiac glycosides may possess anti-cancer properties, possibly by inducing apoptosis in cancer cells. While this area of research is still in its infancy, it highlights the versatility of these compounds and their potential applications in medicine.Despite their benefits, the use of cardiac glycosides is not without risks. Patients must be carefully evaluated before starting treatment, and regular monitoring of drug levels is essential to avoid toxicity. Additionally, interactions with other medications can complicate their use, requiring healthcare providers to exercise caution when prescribing them.In conclusion, cardiac glycosides play a crucial role in the treatment of various heart conditions, significantly improving the quality of life for many patients. Their unique mechanism of action allows for enhanced cardiac function and rhythm regulation. However, the potential for toxicity necessitates vigilant monitoring and careful patient selection. As research continues to uncover new applications for cardiac glycosides, their importance in both cardiology and potentially oncology will likely expand, reaffirming their status as valuable therapeutic agents in modern medicine.

人类身体是一个复杂的系统，依赖各种生化物质来维持其功能。在这些物质中，有一类特别重要的物质被称为心脏糖苷。这些化合物源自植物，几个世纪以来一直在传统医学中用于治疗心脏疾病。心脏糖苷的主要功能是增强心脏收缩的力量，使它们在管理心力衰竭和心律失常中至关重要。本文旨在探讨心脏糖苷在现代医学中的作用、机制和应用。历史上，心脏糖苷是从植物如毛地黄（Digitalis purpurea）和铃兰（Convallaria majalis）中提取的。最著名的心脏糖苷是地高辛，在临床实践中常用。这些化合物通过抑制心脏细胞中的钠钾ATP酶泵来发挥作用，导致细胞内钠水平升高。反过来，这会导致钙离子的流入，增强心肌的收缩性。因此，心脏虚弱的患者可以体验到心输出量的改善，从而减轻呼吸急促和疲劳等症状。除了对心脏收缩的积极影响外，心脏糖苷还对心律有调节作用。它们在治疗心房颤动方面特别有效，这是一种以不规则心跳为特征的疾病。通过减缓房室（AV）结的传导，心脏糖苷帮助恢复更规律的心律。然而，由于其治疗窗口窄，使用这些化合物需要仔细监测；过量服用可能导致毒性，引起恶心、呕吐甚至危及生命的心律失常等症状。心脏糖苷的应用不仅限于心力衰竭和心律失常。研究表明它们在其他领域也可能具有益处，例如癌症治疗。一些研究表明，心脏糖苷可能具有抗癌特性，可能通过诱导癌细胞凋亡来实现。尽管这一研究领域仍处于初期阶段，但它突显了这些化合物的多功能性及其在医学中的潜在应用。尽管有益，使用心脏糖苷并非没有风险。患者在开始治疗之前必须进行仔细评估，定期监测药物水平对于避免毒性至关重要。此外，与其他药物的相互作用可能使其使用复杂，要求医疗提供者在开处方时保持谨慎。总之，心脏糖苷在各种心脏疾病的治疗中发挥着至关重要的作用，显著改善了许多患者的生活质量。它们独特的作用机制允许增强心脏功能和节律调节。然而，毒性的潜在性要求严格的监测和仔细的患者选择。随着研究继续揭示心脏糖苷的新应用，它们在心脏病学和潜在肿瘤学中的重要性可能会扩展，重申其作为现代医学中有价值的治疗剂的地位。