amino acid sequence

简明释义

氨基酸顺序

英英释义

例句

1.Researchers are analyzing the amino acid sequence to identify mutations.

研究人员正在分析氨基酸序列以识别突变。

2.The amino acid sequence of the protein determines its function.

蛋白质的氨基酸序列决定了它的功能。

3.The amino acid sequence is crucial for the stability of the enzyme.

对于酶的稳定性，氨基酸序列至关重要。

4.Bioinformatics tools can predict the amino acid sequence from DNA.

生物信息学工具可以根据DNA预测氨基酸序列。

5.Understanding the amino acid sequence can help in drug design.

理解氨基酸序列可以帮助药物设计。

作文

The study of proteins and their functions is a fundamental aspect of biochemistry and molecular biology. At the core of this study lies the concept of the amino acid sequence, which refers to the specific order of amino acids in a protein. This sequence determines not only the structure of the protein but also its function within a biological system. Each protein is made up of a chain of amino acids, linked together by peptide bonds, forming a unique sequence that is encoded by the organism's DNA. Understanding the amino acid sequence is crucial for several reasons. First, it provides insight into how proteins fold and how their three-dimensional structures are formed. The sequence dictates the interactions between different amino acids, leading to the formation of secondary, tertiary, and quaternary structures. For instance, hydrophobic amino acids tend to cluster together away from water, while hydrophilic amino acids are found on the surface of proteins. This behavior is essential for the proper functioning of enzymes and other proteins, as their shape directly influences their activity.Moreover, variations in the amino acid sequence can lead to significant differences in protein function. Mutations in the genetic code can result in changes to the amino acid sequence, potentially leading to diseases. For example, sickle cell anemia is caused by a single nucleotide change in the gene encoding hemoglobin, leading to an altered amino acid sequence. This small change results in a protein that behaves differently, causing red blood cells to assume a sickle shape, which can block blood flow and lead to severe health complications.In the field of biotechnology, knowledge of the amino acid sequence has paved the way for advancements such as recombinant DNA technology and protein engineering. Scientists can manipulate the genetic sequences that encode proteins, allowing them to create modified proteins with desired properties. This has applications in medicine, agriculture, and industry. For example, insulin used for diabetes treatment is produced through recombinant DNA technology, where the amino acid sequence of human insulin is inserted into bacteria, enabling mass production.Furthermore, the analysis of amino acid sequences is vital in the field of bioinformatics. With the advent of high-throughput sequencing technologies, researchers can now determine the amino acid sequences of thousands of proteins simultaneously. This data can be used to study evolutionary relationships among species, understand metabolic pathways, and identify potential drug targets. By comparing amino acid sequences across different organisms, scientists can gain insights into the conservation of certain proteins and their functions throughout evolution.In conclusion, the amino acid sequence is a critical element in understanding the complexity of life at the molecular level. It not only dictates the structure and function of proteins but also plays a significant role in health and disease. As research continues to advance, our understanding of the amino acid sequence will undoubtedly lead to new discoveries and innovations in various fields, highlighting the importance of this fundamental concept in biology.

蛋白质及其功能的研究是生物化学和分子生物学的基本方面。在这一研究的核心是“氨基酸序列”的概念，它指的是蛋白质中氨基酸的特定顺序。这个序列不仅决定了蛋白质的结构，还决定了其在生物系统中的功能。每个蛋白质由一链氨基酸组成，通过肽键连接在一起，形成一个独特的序列，该序列由生物体的DNA编码。理解氨基酸序列至关重要，原因有几个。首先，它提供了对蛋白质如何折叠以及其三维结构如何形成的洞察。序列决定了不同氨基酸之间的相互作用，从而导致二级、三级和四级结构的形成。例如，疏水性氨基酸往往聚集在一起远离水，而亲水性氨基酸则位于蛋白质的表面。这种行为对于酶和其他蛋白质的正常功能至关重要，因为它们的形状直接影响其活性。此外，氨基酸序列的变化可能导致蛋白质功能的显著差异。遗传密码中的突变可能导致氨基酸序列的变化，从而可能导致疾病。例如，镰状细胞贫血是由于编码血红蛋白的基因中发生单个核苷酸变化，导致氨基酸序列的改变。这一微小的变化导致一种行为不同的蛋白质，使红细胞呈现镰刀状，这可能阻塞血流并导致严重的健康并发症。在生物技术领域，对氨基酸序列的知识为重组DNA技术和蛋白质工程等进展铺平了道路。科学家可以操纵编码蛋白质的基因序列，使他们能够创建具有所需特性的修饰蛋白质。这在医学、农业和工业中都有应用。例如，用于糖尿病治疗的胰岛素是通过重组DNA技术生产的，其中人类胰岛素的氨基酸序列被插入到细菌中，从而实现大规模生产。此外，氨基酸序列的分析在生物信息学领域也至关重要。随着高通量测序技术的出现，研究人员现在可以同时确定成千上万种蛋白质的氨基酸序列。这些数据可用于研究物种间的进化关系，理解代谢途径，识别潜在的药物靶点。通过比较不同生物体的氨基酸序列，科学家可以深入了解某些蛋白质及其功能在整个进化过程中的保守性。总之，氨基酸序列是理解生命复杂性的重要元素。它不仅决定了蛋白质的结构和功能，还在健康和疾病中发挥着重要作用。随着研究的不断推进，我们对氨基酸序列的理解无疑将引领新的发现和各个领域的创新，突显了这一生物学基本概念的重要性。