pyrogens
简明释义
n. 致热源；焦精（pyrogen 的复数）
英英释义
Pyrogens are substances that induce fever when introduced into the body, often produced by bacteria or other pathogens. | 致热原是指当引入体内时会引起发热的物质，通常由细菌或其他病原体产生。 |
单词用法
同义词
反义词
例句
1.The main source of pyrogens is endotoxin.
较主要的热原是内毒素。
2.Of this group of endogenous pyrogens, most is known about interleukin-1(IL-1).
在这组内源性热原中，研究得最清楚的是IL-1。
3.Of this group of endogenous pyrogens, most is known about interleukin-1(IL-1).
在这组内源性热原中，研究得最清楚的是IL-1。
4.In sterile manufacturing, it is crucial to test for pyrogens to ensure product safety.
在无菌生产中，检测致热源至关重要，以确保产品安全。
5.Some vaccines are carefully purified to remove any potential pyrogens.
一些疫苗经过精心净化，以去除任何潜在的致热源。
6.The presence of pyrogens can lead to fever and other inflammatory responses in patients.
存在致热源可能导致患者发热和其他炎症反应。
7.When testing medical devices, the presence of pyrogens must be assessed to prevent adverse reactions.
在测试医疗设备时，必须评估致热源的存在，以防止不良反应。
8.Certain bacteria produce pyrogens that can trigger a strong immune response.
某些细菌产生的致热源可以引发强烈的免疫反应。
作文
In the field of medicine and biology, understanding the concept of pyrogens is essential for diagnosing and treating various conditions. Pyrogens are substances that can induce fever when they enter the body. This phenomenon is a crucial part of the immune response, as fever can help the body fight off infections. There are two main types of pyrogens: exogenous and endogenous. Exogenous pyrogens are typically derived from outside the body, such as bacterial toxins or viruses, while endogenous pyrogens are produced by the body's own immune cells in response to infection or inflammation.The role of pyrogens in fever production is significant. When the body detects an invading pathogen, immune cells release signaling molecules called cytokines. These cytokines travel through the bloodstream to the brain, specifically to the hypothalamus, which is responsible for regulating body temperature. The hypothalamus responds by raising the body's temperature set point, resulting in fever. This increase in temperature can create an environment that is less favorable for pathogens, enhancing the effectiveness of the immune response.Moreover, understanding pyrogens is critical in clinical settings, particularly in the context of medical procedures involving sterile equipment. For instance, when surgical instruments or intravenous fluids are contaminated with pyrogens, they can lead to severe complications, including fever and septic shock. Therefore, healthcare professionals must ensure that all medical equipment is adequately sterilized to eliminate any potential pyrogens.The study of pyrogens also extends to the pharmaceutical industry. In drug development, it is vital to test for the presence of pyrogens in injectable medications. The presence of pyrogens can lead to adverse reactions in patients, making it a critical factor in ensuring drug safety. Various methods, such as the Limulus Amebocyte Lysate (LAL) test, are employed to detect pyrogens in pharmaceutical products.In summary, pyrogens play a significant role in the body's response to infection and have important implications in both clinical and pharmaceutical contexts. Understanding how pyrogens work can help healthcare providers manage fevers effectively and prevent complications arising from contaminated medical products. As research continues to evolve in this area, further insights into the mechanisms of pyrogens may lead to improved treatments and preventive measures against infectious diseases. Thus, the study of pyrogens is not only fascinating but also vital for advancing medical science and improving patient care.
在医学和生物学领域，理解pyrogens的概念对于诊断和治疗各种疾病至关重要。Pyrogens是指能够在进入体内时引起发热的物质。这种现象是免疫反应的重要组成部分，因为发热有助于身体抵抗感染。Pyrogens主要分为两种类型：外源性和内源性。外源性pyrogens通常来源于体外，如细菌毒素或病毒，而内源性pyrogens是在感染或炎症反应中由身体自身的免疫细胞产生的。Pyrogens在发热产生中的作用非常重要。当身体检测到入侵病原体时，免疫细胞会释放称为细胞因子的信号分子。这些细胞因子通过血液循环到达大脑，特别是下丘脑，下丘脑负责调节体温。下丘脑通过提高身体的温度设定点来作出反应，从而导致发热。体温的升高可以创造一个对病原体不利的环境，增强免疫反应的有效性。此外，理解pyrogens在临床环境中至关重要，特别是在涉及无菌设备的医疗程序中。例如，当手术器械或静脉注射液被pyrogens污染时，会导致严重的并发症，包括发热和脓毒性休克。因此，医疗专业人员必须确保所有医疗设备经过适当消毒，以消除任何潜在的pyrogens。Pyrogens的研究还扩展到制药行业。在药物开发中，测试注射药物中是否存在pyrogens至关重要。Pyrogens的存在可能导致患者出现不良反应，因此这是确保药物安全的关键因素。各种方法，例如鲎试剂（LAL）测试，被用来检测药品中的pyrogens。总之，pyrogens在身体对感染的反应中发挥着重要作用，并在临床和制药背景中具有重要意义。理解pyrogens的工作原理可以帮助医疗提供者有效管理发热，并防止因医疗产品污染而引发的并发症。随着这一领域研究的不断发展，对pyrogens机制的进一步了解可能会导致改善感染性疾病的治疗和预防措施。因此，pyrogens的研究不仅令人着迷，而且对推动医学科学和改善患者护理至关重要。
