median lethal time

简明释义

半数致死时间

英英释义

例句

1.In toxicology, understanding the median lethal time 中位致死时间 helps assess the risk of exposure to harmful substances.

在毒理学中，了解中位致死时间 median lethal time 有助于评估接触有害物质的风险。

2.After testing, the scientists reported a median lethal time 中位致死时间 of 48 hours for the tested compound.

经过测试，科学家报告称所测试化合物的中位致死时间 median lethal time 为48小时。

3.The median lethal time 中位致死时间 for the chemical was significantly lower in younger animals compared to adults.

该化学物质的中位致死时间 median lethal time 在年轻动物中明显低于成年动物。

4.The median lethal time 中位致死时间 can vary based on environmental conditions and species affected.

根据环境条件和受影响物种的不同，中位致死时间 median lethal time 可能会有所不同。

5.The researchers conducted a study to determine the median lethal time 中位致死时间 of the new pesticide on aquatic life.

研究人员进行了一项研究，以确定新农药对水生生物的中位致死时间 median lethal time。

作文

In the field of toxicology and pharmacology, understanding the effects of substances on living organisms is crucial. One important concept in this area is the median lethal time, which refers to the time it takes for a substance to cause death in 50% of a test population under controlled conditions. This measure is particularly significant when evaluating the toxicity of chemicals, drugs, or environmental pollutants. It provides researchers and regulatory agencies with essential data to assess risks and make informed decisions regarding safety standards.The median lethal time is often determined through experiments involving various doses of a substance administered to a group of test subjects, such as laboratory animals. By observing the time it takes for half of the subjects to succumb to the effects of the substance, scientists can calculate the median lethal time. This information is vital for establishing safe exposure levels and understanding the potential impact of toxic substances on human health and the environment.For instance, if a new pesticide is being tested, researchers would expose a group of rats to the chemical and monitor their survival over time. If it is found that 50% of the rats die within a specified period after exposure, that duration is recorded as the median lethal time. Such data helps in comparing the toxicity of different substances and determining which ones pose a greater risk to health and safety.Moreover, the median lethal time can vary significantly depending on several factors, including the species being tested, the dosage of the substance, and the method of administration. For example, a substance may have a shorter median lethal time when injected compared to when it is ingested. This variability highlights the importance of context in toxicological studies and the need for careful interpretation of results.Understanding the median lethal time also plays a role in regulatory frameworks. Government agencies, such as the Environmental Protection Agency (EPA) in the United States, rely on such data to set guidelines for permissible levels of exposure to various chemicals. These regulations are designed to protect public health and the environment by ensuring that substances are used safely and responsibly.In addition to its applications in research and regulation, the concept of median lethal time has broader implications in public health. For instance, during a chemical spill or exposure incident, knowing the median lethal time of involved substances can guide emergency response efforts. It can help responders understand how quickly they need to act to mitigate harm to affected populations.Furthermore, education about the median lethal time can raise awareness among the general public regarding the dangers of certain substances. By understanding that some chemicals can be lethal within a short timeframe, individuals can make better-informed decisions about their exposure to potentially hazardous materials.In conclusion, the median lethal time is a critical metric in the fields of toxicology and pharmacology. It provides valuable insights into the lethality of substances and informs regulatory decisions aimed at protecting public health. As we continue to study and understand the effects of various chemicals on living organisms, the significance of the median lethal time will remain paramount in ensuring safety and mitigating risks associated with toxic exposures.

在毒理学和药理学领域，理解物质对生物体的影响至关重要。一个重要的概念是中位致死时间，指的是在受控条件下使测试人群中50%的个体死亡所需的时间。这个测量在评估化学品、药物或环境污染物的毒性时特别重要。它为研究人员和监管机构提供了评估风险和做出安全标准相关明智决策所需的重要数据。中位致死时间通常通过实验来确定，涉及将不同剂量的物质施加于一组测试对象，如实验室动物。通过观察半数受试者在物质影响下死亡所需的时间，科学家可以计算出中位致死时间。这些信息对于建立安全暴露水平以及理解有毒物质对人类健康和环境的潜在影响至关重要。例如，如果正在测试一种新农药，研究人员会将一组老鼠暴露于该化学物质，并监测它们的存活时间。如果发现50%的老鼠在暴露后的一段特定时间内死亡，那么这个持续时间就被记录为中位致死时间。这样的数据有助于比较不同物质的毒性，并确定哪些物质对健康和安全构成更大风险。此外，中位致死时间可能因多个因素而显著变化，包括被测试物种、物质的剂量和给药方法。例如，某种物质在注射时可能具有较短的中位致死时间，而在摄入时则可能较长。这种变异性突显了毒理学研究中上下文的重要性，以及对结果进行仔细解释的必要性。理解中位致死时间在监管框架中也发挥了作用。美国环境保护局（EPA）等政府机构依赖这些数据来设定各种化学物质的允许暴露水平指南。这些法规旨在通过确保物质的安全和负责任使用来保护公众健康和环境。除了在研究和监管中的应用外，中位致死时间的概念在公共健康中也有更广泛的影响。例如，在化学泄漏或暴露事件中，了解所涉及物质的中位致死时间可以指导应急响应工作。它可以帮助响应者理解他们需要多快采取行动以减轻对受影响人群的危害。此外，关于中位致死时间的教育可以提高公众对某些物质危险性的认识。通过理解某些化学物质在短时间内可能致命，个人可以更好地做出关于暴露于潜在危险材料的决策。总之，中位致死时间是毒理学和药理学领域中的一个关键指标。它提供了有关物质致死性的重要见解，并为保护公众健康的监管决策提供信息。随着我们继续研究和理解各种化学物质对生物体的影响，中位致死时间的重要性将在确保安全和减轻与有毒暴露相关的风险方面保持至关重要。