isotopic dilution analysis

简明释义

同位素稀释分析

英英释义

例句

1.By applying isotopic dilution analysis 同位素稀释分析, scientists can accurately measure the isotopic ratios in geological samples.

通过应用同位素稀释分析 isotopic dilution analysis，科学家可以准确测量地质样本中的同位素比率。

2.The pharmaceutical company utilized isotopic dilution analysis 同位素稀释分析 to quantify the active ingredients in their new drug formulation.

制药公司利用同位素稀释分析 isotopic dilution analysis 来量化他们新药配方中的活性成分。

3.Researchers employed isotopic dilution analysis 同位素稀释分析 to trace the source of nutrients in agricultural runoff.

研究人员采用了同位素稀释分析 isotopic dilution analysis 来追踪农业径流中营养物质的来源。

4.In environmental studies, isotopic dilution analysis 同位素稀释分析 is used to determine the concentration of pollutants in water samples.

在环境研究中，同位素稀释分析 isotopic dilution analysis 被用于确定水样中污染物的浓度。

5.In food safety testing, isotopic dilution analysis 同位素稀释分析 helps to identify the presence of contaminants.

在食品安全检测中，同位素稀释分析 isotopic dilution analysis 有助于识别污染物的存在。

作文

In the field of analytical chemistry, various techniques are employed to measure the concentration of substances in a sample. One such method that has gained considerable attention is isotopic dilution analysis. This technique utilizes isotopes—atoms of the same element with different masses—to provide accurate measurements of concentrations in complex mixtures. The fundamental principle behind isotopic dilution analysis is the addition of a known quantity of an isotopically labeled compound to a sample. By measuring the ratio of the isotopes present in the sample before and after the addition, scientists can determine the concentration of the target analyte with high precision.The use of isotopes in this analysis offers several advantages over traditional methods. First and foremost, isotopic dilution analysis significantly reduces the potential for errors caused by matrix effects, which can occur when other components in a sample interfere with the measurement of the target analyte. In complex samples, such as biological fluids or environmental matrices, these interferences can lead to inaccurate results. However, because the isotopic label is distinct, it allows for a clearer distinction between the analyte and other components in the mixture.Moreover, isotopic dilution analysis is highly versatile and can be applied to a wide range of fields, including pharmaceuticals, environmental science, and food safety. For instance, in pharmacokinetics, researchers often use this technique to study drug metabolism by tracing the labeled drug as it moves through the body. In environmental studies, isotopic dilution analysis can help quantify pollutants in water or soil samples, providing crucial data for assessing contamination levels and informing remediation efforts.The process of isotopic dilution analysis typically involves several steps: preparation of the sample, addition of the isotopically labeled standard, thorough mixing, and subsequent measurement using sophisticated instruments such as mass spectrometers. The data obtained from these measurements are then analyzed to calculate the concentration of the target analyte based on the known amount of the isotopic standard added.Despite its many benefits, isotopic dilution analysis does come with some challenges. The selection of appropriate isotopes is critical; they must be stable and not interfere with the sample matrix. Additionally, the cost of isotopes and the required instrumentation can be prohibitive for some laboratories. Nevertheless, the accuracy and reliability of this method often justify the investment, especially in research areas where precise quantification is essential.In conclusion, isotopic dilution analysis is a powerful analytical technique that enhances the accuracy of concentration measurements in various scientific fields. By leveraging the unique properties of isotopes, researchers can overcome many of the limitations associated with conventional methods. As technology advances and the availability of isotopes improves, it is likely that isotopic dilution analysis will become even more widespread, further contributing to our understanding of complex chemical systems and aiding in the development of safer products and cleaner environments.

在分析化学领域，各种技术被用来测量样品中物质的浓度。同位素稀释分析是其中一种受到相当关注的方法。这种技术利用同位素——质量不同的同一元素的原子——来提供复杂混合物中浓度的准确测量。同位素稀释分析的基本原理是向样品中添加已知数量的同位素标记化合物。通过测量添加前后样品中同位素的比率，科学家可以以高精度确定目标分析物的浓度。在这种分析中使用同位素提供了几个优于传统方法的优势。首先，同位素稀释分析显著减少了由于基体效应引起的潜在错误，这种效应可能发生在样品中其他成分干扰目标分析物的测量时。在复杂样品中，如生物液体或环境基质，这些干扰可能导致不准确的结果。然而，由于同位素标记是独特的，它允许在混合物中更清楚地区分分析物和其他成分。此外，同位素稀释分析具有高度的多功能性，可以应用于制药、环境科学和食品安全等广泛领域。例如，在药代动力学研究中，研究人员常常使用这种技术来研究药物代谢，通过追踪标记药物在体内的移动。在环境研究中，同位素稀释分析可以帮助量化水或土壤样品中的污染物，为评估污染水平和指导修复工作提供关键数据。同位素稀释分析的过程通常包括几个步骤：样品准备、添加同位素标记标准、充分混合以及使用质谱仪等先进仪器进行后续测量。从这些测量中获得的数据随后被分析，以根据添加的已知同位素标准的量计算目标分析物的浓度。尽管有许多优点，同位素稀释分析也面临一些挑战。选择合适的同位素至关重要；它们必须是稳定的，并且不会干扰样品基质。此外，同位素和所需仪器的成本对一些实验室来说可能是个负担。然而，这种方法的准确性和可靠性往往证明了投资的合理性，尤其是在需要精确量化的研究领域。总之，同位素稀释分析是一种强大的分析技术，增强了各科学领域中浓度测量的准确性。通过利用同位素的独特性质，研究人员可以克服许多与传统方法相关的局限性。随着技术的进步和同位素可用性的提高，同位素稀释分析可能会变得更加普及，进一步促进我们对复杂化学系统的理解，并有助于开发更安全的产品和更清洁的环境。