apomorphine

简明释义

英[ˌæpəˈmɔːfiːn]美[ˌæpəˈmɔrfin]

n. [药] 阿朴吗啡；[药] 脱水吗啡

英英释义

单词用法

同义词

反义词

例句

1.ConclusionA single apomorphine might disrupt the working memory of reversal learning in rats, but not affect the working memory of normal learning and the process of reversal learning.

结论单独一次阿扑吗啡注射可能干扰大鼠逆反学习的工作记忆，但不影响正常学习的工作记忆和逆反学习的过程。

2.When test performance was evaluated 40 minutes after subjects received apomorphine, the mean reaction times were 392 minutes in alcohol-dependent subjects and 417 minutes in controls.

当受试者服用阿朴吗啡40分钟后的测试结果为，酒精依赖组的平均反应时间为392分钟，而对照组为417分钟。

3.Objective To investigate the possible neuroprotective effect of dopamine(DA) receptor agonist R-apomorphine(R-APO) on the 6-hydroxydopamine(6-OHDA)-induced rat model of Parkinson's disease.

目的探讨阿扑吗啡是否对6-羟基多巴胺毁损纹状体帕金森病鼠模型有神经保护作用。

4.For reversal learning, the mean correct number of rats in apomorphine group was significantly lower than its in saline group.

对于逆反学习，阿扑吗啡注射组动物的正确次数较对照组显著降低。

5.After transplanting NIH-3T3-TH engineered cells into the lesioned striatum by stereotaxic technique, the rats were tested for rotational behavior induced by apomorphine.

通过脑立体定位技术，将表达TH的NIH-3T3—TH工程细胞注入模型鼠损毁侧纹状体，观察阿朴吗啡诱导的旋转行为改善情况。

6.Results of apomorphine-induced rotation behavior experimentrSingle stimulation at different intensity could not decrease the rotation behavior in Parkinson rats;

阿朴吗啡诱发的旋转实验结果：不同强度的单次刺激不能降低帕金森病大鼠阿朴吗啡诱发的旋转行为；

7.Objective To investigate the possible neuroprotective effect of dopamine(DA) receptor agonist R-apomorphine(R-APO) on the 6-hydroxydopamine(6-OHDA)-induced rat model of Parkinson's disease.

目的探讨阿扑吗啡是否对6-羟基多巴胺毁损纹状体帕金森病鼠模型有神经保护作用。

8.MethodsA home pigeon CuSO 4-vomiting model and dog -apomorphine vomiting model were used to observe the latent period of vomiting and the frequency of vomiting.

方法分别采用家鸽硫酸铜致吐模型及犬去水吗啡致吐模型，以观察呕吐潜伏期及呕吐频率。

9.In cases of opioid overdose, apomorphine can be used as an antidote.

在阿片类药物过量的情况下，可以使用阿扑吗啡作为解毒剂。

10.The side effects of apomorphine include dizziness and drowsiness.

使用阿扑吗啡的副作用包括头晕和嗜睡。

11.Apomorphine is administered via injection for rapid effect.

阿扑吗啡通过注射给药，以实现快速效果。

12.The doctor prescribed apomorphine for the patient's severe nausea.

医生为患者的严重恶心开了阿扑吗啡。

13.Research shows that apomorphine may help improve motor function in Parkinson's disease patients.

研究表明，阿扑吗啡可能有助于改善帕金森病患者的运动功能。

作文

Apomorphine is a drug that has been used for various medical purposes, particularly in the treatment of Parkinson's disease. It is classified as a dopamine agonist, which means it mimics the action of dopamine in the brain. Dopamine is a neurotransmitter that plays a crucial role in controlling movement and coordination. In patients with Parkinson's disease, the levels of dopamine are significantly reduced, leading to symptoms such as tremors, stiffness, and difficulty in movement. The introduction of apomorphine into their treatment regimen can help alleviate these symptoms by stimulating dopamine receptors. This makes apomorphine an essential medication for many individuals suffering from this debilitating disease.The mechanism of action of apomorphine involves its ability to activate dopamine receptors, particularly the D2 subtype, which are found in various regions of the brain. By doing so, apomorphine can improve motor function and reduce the severity of symptoms associated with Parkinson's disease. It is often administered through subcutaneous injection, allowing for rapid absorption into the bloodstream. This route of administration is particularly beneficial for patients who may have difficulty swallowing pills or those who require immediate relief from their symptoms.In addition to its use in Parkinson's disease, apomorphine has also been explored for other conditions, such as erectile dysfunction. In this context, apomorphine works by increasing blood flow to the penis, thereby facilitating an erection. This dual application highlights the versatility of apomorphine as a therapeutic agent, although its use for erectile dysfunction is less common than its application in treating Parkinson's disease.Despite its benefits, the use of apomorphine is not without side effects. Common adverse effects include nausea, vomiting, and drowsiness. Patients may also experience dyskinesias, which are involuntary movements that can occur as a result of the drug's action on the brain. It is important for healthcare providers to monitor patients closely when initiating apomorphine therapy and to adjust dosages as necessary to minimize these side effects.Furthermore, the use of apomorphine requires careful consideration of the patient's overall health status and any other medications they may be taking. Drug interactions can occur, and certain medical conditions may contraindicate the use of apomorphine. Therefore, a comprehensive evaluation by a healthcare professional is essential before starting treatment.In conclusion, apomorphine serves as a vital tool in the management of Parkinson's disease and has potential applications in other areas of medicine. Its ability to mimic dopamine's effects in the brain provides significant relief for patients struggling with motor symptoms. However, the importance of monitoring and managing side effects cannot be overstated. As research continues, we may uncover even more uses for apomorphine, further solidifying its place in modern medicine. Understanding the role of apomorphine in therapeutic contexts is crucial for both healthcare providers and patients alike, ensuring that its benefits can be maximized while minimizing potential risks.

阿扑吗啡是一种药物，已被用于多种医疗目的，特别是在帕金森病的治疗中。它被归类为多巴胺激动剂，这意味着它在大脑中模仿多巴胺的作用。多巴胺是一种神经递质，在控制运动和协调方面起着至关重要的作用。在帕金森病患者中，多巴胺水平显著降低，导致颤抖、僵硬和运动困难等症状。将阿扑吗啡引入他们的治疗方案中可以通过刺激多巴胺受体来缓解这些症状。这使得阿扑吗啡成为许多患有这种严重疾病的个体的重要药物。阿扑吗啡的作用机制涉及其激活多巴胺受体的能力，特别是D2亚型，这些受体存在于大脑的各个区域。通过这样做，阿扑吗啡可以改善运动功能并减少与帕金森病相关的症状的严重程度。它通常通过皮下注射给药，使其迅速吸收到血液中。这种给药途径对于那些可能难以吞咽药片或需要立即缓解症状的患者尤其有益。除了用于帕金森病外，阿扑吗啡还被探讨用于其他疾病，如勃起功能障碍。在这种情况下，阿扑吗啡通过增加阴茎的血流量来促进勃起。这种双重应用突显了阿扑吗啡作为治疗剂的多功能性，尽管其在治疗勃起功能障碍中的使用不如在治疗帕金森病中的应用普遍。尽管有其好处，阿扑吗啡的使用并非没有副作用。常见的不良反应包括恶心、呕吐和嗜睡。患者还可能经历运动障碍，即由于药物对大脑的作用而发生的非自愿运动。在开始阿扑吗啡治疗时，医疗提供者密切监测患者的情况并根据需要调整剂量，以尽量减少这些副作用是非常重要的。此外，使用阿扑吗啡需要仔细考虑患者的整体健康状况以及他们可能正在服用的其他药物。可能会发生药物相互作用，某些医疗条件可能会禁忌使用阿扑吗啡。因此，在开始治疗之前，医疗专业人员的全面评估是必不可少的。总之，阿扑吗啡在帕金森病的管理中发挥着至关重要的作用，并在医学的其他领域有潜在应用。它模拟多巴胺在大脑中的作用，为苦于运动症状的患者提供了显著的缓解。然而，监测和管理副作用的重要性不容小觑。随着研究的继续，我们可能会发现阿扑吗啡更多的用途，进一步巩固其在现代医学中的地位。理解阿扑吗啡在治疗背景中的作用对医疗提供者和患者而言至关重要，确保能够最大限度地发挥其好处，同时最小化潜在风险。