cinchonine

简明释义

英[ˈsɪŋkəniːn]美[ˈsɪnkəˌnin]

n. 辛可宁，金鸡纳宁

英英释义

单词用法

同义词

反义词

例句

1.A cinchonine imprinted chiral monolithic column was prepared for the separation of the diastereomers of cinchonine and cinchonidine by in situ molecular imprinting technique.

采用原位分子印迹技术，单步制备了一种辛可宁印迹的手性整体柱。

2.Working with Pelletier, he isolated quinine, strychnine, brucine, cinchonine, veratrine, and colchicine, some of which became widely used as drugs.

他与佩尔蒂埃合作，分离出了奎宁、土的宁、番禾鳖宁、弱金鸡钠碱和秋水仙碱，其中一些被作为药物广泛使用。

3.A cinchonine imprinted chiral monolithic column was prepared for the separation of the diastereomers of cinchonine and cinchonidine by in situ molecular imprinting technique.

采用原位分子印迹技术，单步制备了一种辛可宁印迹的手性整体柱。

4.Two chiral P, N-ligands were synthesized in high yields from natural quinine and cinchonine under mild conditions.

以价廉的天然产物辛可宁和奎宁为原料，在温和的条件下方便地合成了两个手性膦氮配体。

5.Diastereomers of cinchonine and cinchonidine were fully separated both under isocratic and gradient elutions on the chiral monolithic column.

在等度及梯度洗脱条件下，非对映异构体辛可宁与辛可尼丁被完全分离。

6.The extraction of cinchonine from cinchona bark is a traditional method used for centuries.

从金鸡纳树树皮中提取奎宁是一个使用了几个世纪的传统方法。

7.In some countries, cinchonine is used as a treatment for malaria.

在一些国家，奎宁被用作疟疾的治疗。

8.The compound cinchonine is often used in the synthesis of various pharmaceuticals.

化合物奎宁常用于合成各种药物。

9.Due to its bitter taste, cinchonine is sometimes added to herbal medicines.

由于其苦味，奎宁有时被添加到草药中。

10.Researchers found that cinchonine can act as a chiral auxiliary in organic reactions.

研究人员发现奎宁可以作为有机反应中的手性辅助剂。

作文

Cinchonine is an alkaloid derived from the bark of the cinchona tree, which is native to South America. This compound has been extensively studied for its medicinal properties and has played a significant role in the history of medicine. The cinchona tree was traditionally used by indigenous people for its fever-reducing effects, particularly for treating malaria. In the early 17th century, European colonists learned about the therapeutic uses of cinchona bark, leading to its introduction into Western medicine. Today, cinchonine (金鸡纳碱) is recognized not only for its historical significance but also for its various applications in modern pharmacology.One of the most notable uses of cinchonine (金鸡纳碱) is as an antimalarial agent. It is structurally similar to quinine, another well-known alkaloid that has been used to combat malaria. While quinine has largely taken precedence in treatment protocols, cinchonine (金鸡纳碱) still holds value in certain contexts, particularly in cases where patients may have developed resistance to other antimalarial drugs. Research continues to explore the efficacy of cinchonine (金鸡纳碱) and its derivatives, aiming to enhance their therapeutic potential against malaria and other diseases.In addition to its antimalarial properties, cinchonine (金鸡纳碱) has shown promise in other areas of medicine. For instance, it has been investigated for its analgesic and anti-inflammatory effects. Some studies suggest that cinchonine (金鸡纳碱) may help alleviate pain and reduce inflammation, making it a candidate for further research in pain management therapies. Moreover, this compound has been examined for its potential use in treating certain types of cancer, although more extensive clinical trials are necessary to establish its effectiveness and safety in oncology.The chemical structure of cinchonine (金鸡纳碱) is complex, featuring multiple rings and functional groups that contribute to its biological activity. Understanding the pharmacokinetics and pharmacodynamics of cinchonine (金鸡纳碱) is crucial for developing effective formulations and dosage regimens. Scientists are particularly interested in how cinchonine (金鸡纳碱) interacts with cellular pathways and its mechanism of action at the molecular level.Despite its benefits, there are challenges associated with the use of cinchonine (金鸡纳碱). Like many alkaloids, it can exhibit side effects, and its use must be carefully monitored. Adverse reactions can occur, especially in individuals who may have sensitivities or allergies to compounds derived from the cinchona tree. Therefore, healthcare providers must weigh the potential benefits against the risks when considering cinchonine (金鸡纳碱) as a treatment option.In conclusion, cinchonine (金鸡纳碱) is a fascinating alkaloid with a rich history and promising future in medicine. Its role in the treatment of malaria and other conditions highlights the importance of natural compounds in drug development. As research advances, we may uncover new applications for cinchonine (金鸡纳碱) that could lead to improved health outcomes for patients worldwide. The continued exploration of this compound serves as a reminder of the invaluable contributions that traditional medicine can make to contemporary healthcare practices.

金鸡纳碱是从金鸡纳树的树皮中提取的一种生物碱，原产于南美洲。该化合物因其药用特性而受到广泛研究，并在医学历史上发挥了重要作用。金鸡纳树传统上被土著人民用于降低发热，特别是治疗疟疾。在17世纪初，欧洲殖民者了解到金鸡纳树皮的治疗用途，从而将其引入西方医学。如今，cinchonine（金鸡纳碱）不仅因其历史意义而受到认可，还因其在现代药理学中的各种应用而受到重视。cinchonine（金鸡纳碱）最显著的用途之一是作为抗疟疾药物。它的结构与另一种著名的生物碱奎宁相似，后者已被用于对抗疟疾。尽管奎宁在治疗方案中占据了主导地位，但在某些情况下，患者可能对其他抗疟疾药物产生耐药性，这时cinchonine（金鸡纳碱）仍然具有价值。研究持续探索cinchonine（金鸡纳碱）及其衍生物的疗效，旨在增强其对抗疟疾和其他疾病的治疗潜力。除了抗疟疾特性外，cinchonine（金鸡纳碱）在医学的其他领域也显示出前景。例如，它已被研究其镇痛和抗炎效果。一些研究表明，cinchonine（金鸡纳碱）可能有助于缓解疼痛并减少炎症，使其成为进一步研究疼痛管理疗法的候选药物。此外，该化合物还被检验用于治疗某些类型的癌症，尽管需要更多的临床试验来确定其在肿瘤学中的有效性和安全性。cinchonine（金鸡纳碱）的化学结构复杂，具有多个环和功能基团，促成其生物活性。理解cinchonine（金鸡纳碱）的药代动力学和药效学对开发有效的制剂和剂量方案至关重要。科学家们特别关注cinchonine（金鸡纳碱）如何与细胞途径相互作用及其在分子水平上的作用机制。尽管有其益处，但使用cinchonine（金鸡纳碱）也面临挑战。像许多生物碱一样，它可能表现出副作用，使用时必须仔细监控。特别是在对金鸡纳树提取物敏感或过敏的人群中，可能会出现不良反应。因此，医疗提供者在考虑cinchonine（金鸡纳碱）作为治疗选择时，必须权衡潜在的益处与风险。总之，cinchonine（金鸡纳碱）是一种迷人的生物碱，在医学上具有丰富的历史和光明的未来。它在疟疾和其他疾病治疗中的作用突显了天然化合物在药物开发中的重要性。随着研究的推进，我们可能会发现cinchonine（金鸡纳碱）的新应用，从而改善全球患者的健康结果。对该化合物的持续探索提醒我们，传统医学对当代医疗实践可以做出不可估量的贡献。