phosphoprotein

简明释义

英[ˌfɒsfə(ʊ)ˈprəʊtiːn]美[ˌfɑsfoˈprotiɪn]

n. 磷蛋白质；[生化] 磷朊

英英释义

单词用法

同义词

反义词

例句

1.These compounds are targeted for use as inhibitors of SH2 domain binding with a phosphoprotein, and are contemplated for use in a number of diseases including cancer.

这些化合物主要针对作为SH2结构与磷酸结合域抑制剂的使用，是在一个许多疾病，包括癌症的使用设想。

2.These compounds are targeted for use as inhibitors of SH2 domain binding with a phosphoprotein, and are contemplated for use in a number of diseases including cancer.

这些化合物主要针对作为SH2结构与磷酸结合域抑制剂的使用，是在一个许多疾病，包括癌症的使用设想。

3.In this study, a novel approach of enrichment of phosphopeptides has been developed prior to phosphoprotein analysis by mass spectrometry.

基于此，本文开展了一种磷酸肽富集的新方法研究，并将其应用于复杂样品的分析。

4.Osteopontin is a multifunctional phosphoprotein containing GRGDS sequence which functions in cell adhesion and chemotaxis.

骨桥蛋白是一种具有多种功能的磷酸化糖蛋白，其中含有特异的与细胞黏附及迁移有关的GRGDS序列。

5.Objective:To observe expression of dentin phosphoprotein (DPP) in developing rat teeth, to get a better understanding on teeth development.

目的；观察牙本质磷蛋白（DPP）在大鼠牙齿发育各期的表达，探讨其在牙齿发育中的作用。

6.The study revealed that the levels of phosphoprotein (磷酸化蛋白) in the cell increased significantly after treatment.

研究表明，经过处理后，细胞中phosphoprotein (磷酸化蛋白) 的水平显著增加。

7.The enzyme responsible for adding phosphate groups to phosphoprotein (磷酸化蛋白) is known as a kinase.

负责将磷酸基团添加到phosphoprotein (磷酸化蛋白) 的酶被称为激酶。

8.Detection of phosphoprotein (磷酸化蛋白) can be performed using Western blotting techniques.

可以使用西方印迹技术检测phosphoprotein (磷酸化蛋白)。

9.Certain signaling pathways are activated by the phosphorylation of phosphoprotein (磷酸化蛋白).

某些信号通路通过phosphoprotein (磷酸化蛋白) 的磷酸化被激活。

10.Researchers are investigating the role of phosphoprotein (磷酸化蛋白) in cancer progression.

研究人员正在调查phosphoprotein (磷酸化蛋白) 在癌症进展中的作用。

作文

Phosphoproteins are a fascinating class of proteins that have garnered significant attention in the field of biochemistry and molecular biology. These proteins are characterized by the presence of phosphate groups, which are covalently attached to specific amino acids within the protein structure. The addition of phosphate groups can alter the protein's function, activity, and interaction with other molecules, making them essential in various biological processes. In this essay, we will explore the significance of phosphoprotein (磷蛋白) in cellular signaling, metabolism, and disease. One of the most critical roles of phosphoprotein (磷蛋白) is in cellular signaling pathways. Phosphorylation, the process of adding a phosphate group to a protein, can activate or deactivate enzymes and receptors, thereby influencing cellular responses to external stimuli. For instance, in the insulin signaling pathway, the phosphorylation of specific proteins allows cells to uptake glucose from the bloodstream, demonstrating how phosphoprotein (磷蛋白) plays a pivotal role in regulating energy metabolism. This mechanism highlights the importance of phosphoprotein (磷蛋白) in maintaining homeostasis within the body. Moreover, phosphoprotein (磷蛋白) are involved in various metabolic pathways. They can act as enzymes that catalyze biochemical reactions, and their activity is often regulated through phosphorylation. For example, glycogen phosphorylase, a key enzyme in glycogen breakdown, is activated by phosphorylation. This regulation ensures that energy is available when needed, showcasing how phosphoprotein (磷蛋白) are integral to metabolic control. In addition to their roles in normal cellular functions, phosphoprotein (磷蛋白) are also implicated in several diseases, including cancer. Abnormal phosphorylation patterns can lead to uncontrolled cell growth and division, a hallmark of cancerous cells. For instance, mutations in kinases, the enzymes responsible for adding phosphate groups, can result in persistent activation of signaling pathways that promote tumorigenesis. Understanding the role of phosphoprotein (磷蛋白) in these processes opens up new avenues for targeted therapies that aim to inhibit the aberrant signaling caused by faulty phosphorylation. Research into phosphoprotein (磷蛋白) has expanded significantly in recent years, aided by advanced techniques such as mass spectrometry and phosphoproteomics. These technologies allow scientists to analyze phosphorylation changes on a large scale, providing insights into how phosphoprotein (磷蛋白) function in various contexts, including development, stress responses, and disease progression. In conclusion, phosphoprotein (磷蛋白) play crucial roles in cellular signaling, metabolism, and disease. Their ability to undergo phosphorylation makes them dynamic regulators of biological processes, influencing everything from energy homeostasis to cancer progression. As research continues to unveil the complexities of phosphoprotein (磷蛋白), we can anticipate the development of novel therapeutic strategies aimed at targeting these proteins to treat various diseases effectively. The study of phosphoprotein (磷蛋白) not only enhances our understanding of cellular functions but also emphasizes the intricate connections between protein modifications and health.

磷蛋白是一类引人注目的蛋白质，在生物化学和分子生物学领域引起了广泛关注。这些蛋白质的特点是含有磷酸基团，这些基团以共价方式附着在蛋白质结构中的特定氨基酸上。磷酸基团的添加可以改变蛋白质的功能、活性以及与其他分子的相互作用，使其在各种生物过程中至关重要。在本文中，我们将探讨磷蛋白在细胞信号传导、代谢和疾病中的重要性。磷蛋白在细胞信号传导途径中发挥着至关重要的作用。磷酸化是将磷酸基团添加到蛋白质上的过程，可以激活或失活酶和受体，从而影响细胞对外部刺激的反应。例如，在胰岛素信号传导途径中，特定蛋白质的磷酸化使细胞能够从血液中摄取葡萄糖，展示了磷蛋白在调节能量代谢中的关键作用。这一机制凸显了磷蛋白在维持体内稳态中的重要性。此外，磷蛋白还参与多种代谢途径。它们可以作为催化生化反应的酶，其活性通常通过磷酸化进行调节。例如，糖原磷酸化酶是糖原分解中的关键酶，通过磷酸化被激活。这种调节确保在需要时能量可用，展示了磷蛋白在代谢控制中的重要性。除了在正常细胞功能中的作用，磷蛋白还与多种疾病有关，包括癌症。异常的磷酸化模式可能导致细胞的无控制生长和分裂，这是癌细胞的一个标志。例如，负责添加磷酸基团的酶——激酶的突变，可能导致促进肿瘤发生的信号通路的持续激活。了解磷蛋白在这些过程中所起的作用，为针对性治疗开辟了新的途径，旨在抑制由错误磷酸化引起的异常信号传导。近年来，对磷蛋白的研究显著增加，得益于质谱法和磷酸蛋白组学等先进技术。这些技术使科学家能够大规模分析磷酸化变化，提供关于磷蛋白在不同背景下如何发挥作用的见解，包括发育、应激反应和疾病进展。总之，磷蛋白在细胞信号传导、代谢和疾病中发挥着至关重要的作用。它们经历磷酸化的能力使其成为生物过程的动态调节因子，影响从能量稳态到癌症进展的方方面面。随着研究的持续深入，揭示了磷蛋白的复杂性，我们可以预见开发出新型治疗策略，旨在有效靶向这些蛋白质以治疗各种疾病。对磷蛋白的研究不仅增强了我们对细胞功能的理解，还强调了蛋白质修饰与健康之间的复杂联系。