liposome

简明释义

[ˈlɪpəsəʊm;ˈlaɪpəsəʊm][ˈlɪpəsoʊmˌˈlaɪpəsoʊm]

n. [生化] 脂质体

英英释义

A liposome is a spherical vesicle composed of one or more phospholipid bilayers, used to deliver drugs or genetic material into cells.

脂质体是一种由一个或多个磷脂双层组成的球形囊泡,用于将药物或遗传物质输送到细胞内。

单词用法

liposome delivery system

脂质体输送系统

liposome-based drug

基于脂质体的药物

liposome technology

脂质体技术

formulate liposomes

制备脂质体

stability of liposomes

脂质体的稳定性

liposomal encapsulation

脂质体包封

同义词

vesicle

囊泡

Vesicles are often used in cellular transport.

囊泡常用于细胞运输。

nanocarrier

纳米载体

Nanocarriers can enhance drug delivery efficiency.

纳米载体可以提高药物传递效率。

lipid bilayer

脂质双层

The lipid bilayer is a fundamental component of cell membranes.

脂质双层是细胞膜的基本组成部分。

反义词

micelle

胶束

Micelles can be used to solubilize hydrophobic drugs.

胶束可以用于溶解疏水性药物。

free drug

游离药物

Free drugs may have higher toxicity compared to liposomal formulations.

与脂质体制剂相比,游离药物可能具有更高的毒性。

例句

1.Antibody can be linked to liposome particles by covalent binding.

抗体能通过共价键结合在脂质体颗粒上。

2.Conclusion Magnetic doxorubicin stealth liposome as a new anti-tumor drug carrier may have a favorable clinical prospect.

结论磁性阿霉素隐形脂质体作为一种新型抗肿瘤药物显示了良好的应用前景。

3.Conclusion: This methods is simple, quick, accurate and suitable for the quality control for Matrine Liposome.

结论:本方法准确、简单、快捷,适用于苦参碱脂质体的质量控制。

4.RESULT:The EE of liposome reached 80%, and the release rule in vitro was subject to the first order model.

结果制得脂质体的包封率约为80%,脂质体的体外释放规律符合一级动力学过程。

5.Objective To explore the best formula of the 0 5% liposome podophyllotoxin chitosan film.

目的探讨0 5 %脂质体鬼臼毒素壳聚糖膜剂制备的最佳配方。

6.Liposome SOD from cactus is prepared by reverse-phase evaporation.

采用逆相蒸发法制备仙人掌sod脂质体。

7.Objective To establish preparation of matrine liposome.

目的建立苦参碱脂质体的制备工艺。

8.Azithromycin liposome was prepared with the granular soya lecithin by reverse evaporation method.

采用逆相蒸发法,利用大豆粉状磷脂制备阿奇霉素脂质体。

9.The dual-ligand formulations are therefore likely to be heterogeneous in the actual number of ligands per liposome.

在每个脂质体实际的配体数目中,双倍配体模式可能是不均一的。

10.In cosmetics, liposomes are used to deliver active ingredients more effectively.

在化妆品中,脂质体用于更有效地传递活性成分。

11.The new vaccine is encapsulated in liposomes to enhance its effectiveness.

新疫苗被封装在脂质体中以增强其有效性。

12.Researchers are studying the use of liposomes to improve drug delivery systems.

研究人员正在研究使用脂质体来改善药物传递系统。

13.The formulation includes liposomes that help in reducing side effects.

该配方包含脂质体,有助于减少副作用。

14.Scientists have developed a new method to create liposomes for targeted therapy.

科学家们开发了一种新方法来制造用于靶向治疗的脂质体

作文

In the realm of biomedical science, the term liposome refers to a spherical vesicle composed of lipid bilayers that can encapsulate both hydrophilic and hydrophobic substances. This unique structure allows liposomes to serve as effective delivery systems for drugs, genes, and other therapeutic agents. The significance of liposomes in drug delivery cannot be overstated, as they enhance the bioavailability of poorly soluble drugs and minimize side effects by targeting specific cells or tissues. Historically, the discovery of liposomes dates back to the early 1960s when researchers began exploring the potential of phospholipids to form vesicles in aqueous solutions. Since then, extensive research has been conducted to optimize their formulation and application in various medical fields. One of the most notable applications of liposomes is in cancer therapy, where they are used to deliver chemotherapeutic agents directly to tumor cells, thereby reducing the impact on healthy tissues. This targeted approach not only improves the efficacy of the treatment but also significantly decreases the adverse effects commonly associated with traditional chemotherapy.Moreover, liposomes are also utilized in vaccine development. For instance, certain vaccines incorporate liposomes as adjuvants to enhance the immune response. By delivering antigens in a manner that mimics natural infection, liposomes can stimulate a more robust and long-lasting immunity. This innovative use of liposomes has revolutionized vaccine formulations, leading to more effective immunization strategies against various infectious diseases.The versatility of liposomes extends beyond pharmaceuticals; they are also employed in cosmetic formulations. Many skincare products now feature liposomes as carriers for active ingredients, allowing for deeper penetration into the skin and improved efficacy. This application highlights the broad potential of liposomes in enhancing product performance across different industries.Despite their advantages, the production of liposomes poses several challenges. Factors such as size, charge, and stability must be carefully controlled to ensure optimal performance. Researchers are continuously working on novel techniques to improve the scalability and reproducibility of liposome formulations. Advances in nanotechnology have opened new avenues for the development of smart liposomes that can release their payload in response to specific stimuli, such as pH changes or temperature fluctuations. These innovations promise to further enhance the therapeutic applications of liposomes.In conclusion, liposomes represent a significant advancement in drug delivery systems, offering numerous benefits in terms of targeting, efficacy, and safety. Their role in modern medicine, particularly in cancer therapy and vaccine development, underscores their importance in improving patient outcomes. As research continues to unveil new possibilities, liposomes are poised to play an even more critical role in the future of healthcare, making them a subject of great interest for scientists and clinicians alike.

在生物医学科学领域,术语脂质体指的是由脂质双层组成的球形囊泡,可以包裹亲水性和疏水性物质。这种独特的结构使得脂质体能够作为有效的药物、基因和其他治疗剂的递送系统。脂质体在药物递送中的重要性不容小觑,因为它们提高了溶解性差的药物的生物利用度,并通过靶向特定细胞或组织来最小化副作用。历史上,脂质体的发现可以追溯到20世纪60年代初,当时研究人员开始探索磷脂在水相溶液中形成囊泡的潜力。从那时起,进行了广泛的研究,以优化其配方和在各种医学领域的应用。其中一个最显著的应用是在癌症治疗中,脂质体用于将化疗药物直接递送到肿瘤细胞,从而减少对健康组织的影响。这种靶向方法不仅提高了治疗的有效性,而且显著降低了与传统化疗相关的不良反应。此外,脂质体还被用于疫苗开发。例如,某些疫苗将脂质体作为佐剂,以增强免疫反应。通过以模仿自然感染的方式递送抗原,脂质体可以刺激更强大和持久的免疫力。这种对脂质体的创新使用彻底改变了疫苗配方,导致针对各种传染病的更有效的免疫策略。脂质体的多功能性超越了药物领域;它们也被用于化妆品配方。许多护肤产品现在将脂质体作为活性成分的载体,从而允许更深层次的渗透到皮肤中并提高功效。这一应用突显了脂质体在提升各行业产品性能方面的广泛潜力。尽管脂质体具有诸多优势,但其生产仍然面临一些挑战。必须仔细控制大小、电荷和稳定性等因素,以确保最佳性能。研究人员不断致力于新技术,以改善脂质体配方的可扩展性和可重复性。纳米技术的进步为开发智能脂质体开辟了新的途径,这些脂质体可以根据特定刺激(如pH变化或温度波动)释放其负载。这些创新有望进一步增强脂质体的治疗应用。总之,脂质体代表了药物递送系统的一项重大进展,在靶向、有效性和安全性方面提供了众多好处。它们在现代医学中的作用,特别是在癌症治疗和疫苗开发中的重要性,强调了它们在改善患者结果中的重要性。随着研究继续揭示新的可能性,脂质体有望在未来的医疗保健中发挥更关键的作用,使其成为科学家和临床医生都非常感兴趣的主题。