proinsulin
简明释义
英[prəʊˈɪnsjʊlɪn]美[proʊˈɪnsəlɪn]
n. [生化] 胰岛素原
英英释义
Proinsulin is a precursor molecule to insulin, produced in the pancreas, that undergoes enzymatic cleavage to form active insulin and C-peptide. | 前胰岛素是胰腺中产生的一种胰岛素前体分子,通过酶切作用形成活性胰岛素和C肽。 |
单词用法
proinsulin转化 | |
proinsulin分泌 | |
proinsulin检测 | |
proinsulin合成 | |
高proinsulin水平 | |
proinsulin加工 | |
proinsulin与胰岛素的关系 |
同义词
反义词
胰岛素 | 胰岛素对于调节血糖水平至关重要。 | ||
胰高血糖素 | Glucagon works to increase blood sugar levels when they are too low. | 胰高血糖素在血糖过低时起到提高血糖水平的作用。 |
例句
1.Receptor binding activity of the two mutants gives 66% and 54% of that of human proinsulin, respectively, while radio immuno activity drops to 22% and 9%.
两者的胰岛素受体活性分别为人胰岛素原的66%及54%,而胰岛素的放射免疫活性分别降为人胰岛素原的22%及9%。
2.The cells combined human proinsulin gene has the ability of producing insulin with increase in glucose concentration in vitro.
所构建的重组人胰岛素原基因能指导靶细胞随葡萄糖浓度的变化调节胰岛素分泌。
3.Main Outcome Measures: glucose, insulin, proinsulin, glucagon, GIP and GLP-1 levels were measured after 50 gr oral glucose.
主要观察指标:口服50gr葡萄糖以后检测葡萄糖、胰岛素、胰岛素原、胰高血糖素、抑胃肽和胰高血糖素样肽- 1的水平。
4.MBHA resin is relatively inexpensive. The new method is another way for the preparation of human proinsulin C-peptide.
MBHA树脂相对价格便宜,此方法是制备人胰岛素原C肽的另一种尝试。
5.Probe, Proinsulin Probe, Rat, Biotin.
前胰岛素探针,大鼠,生物素。
6.Proinsulin is formed in rough endoplasmic reticulum.
胰岛素原在粗糙型内质网中合成。
7.The secretion expression vector of fusion gene in E. coli has constructed by fussing the proinsulin gene to the gene of staphylococcal protein a.
将胰岛素原基因融合到金色葡萄球菌蛋白a的基因上,构建成大肠杆菌中基因融合的外分泌表达载体。
8.Optimization of the renaturation conditions for recombinant human proinsulin inclusion bodies expressed in E.
对大肠杆菌表达的重组人胰岛素原包涵体蛋白的变性复性条件进行了优化。
9.Measuring levels of proinsulin 胰岛素前体 can help diagnose certain types of diabetes.
测量proinsulin胰岛素前体的水平可以帮助诊断某些类型的糖尿病。
10.High levels of proinsulin 胰岛素前体 in the blood can indicate insulin resistance.
血液中高水平的proinsulin胰岛素前体可能表明胰岛素抵抗。
11.The pancreas produces large amounts of proinsulin 胰岛素前体 before converting it into insulin.
胰腺在将其转化为胰岛素之前会产生大量的proinsulin胰岛素前体。
12.Researchers are studying how proinsulin 胰岛素前体 affects metabolic processes.
研究人员正在研究proinsulin胰岛素前体如何影响新陈代谢过程。
13.In diabetes, the conversion of proinsulin 胰岛素前体 to insulin may be impaired.
在糖尿病中,proinsulin胰岛素前体转化为胰岛素的过程可能受到损害。
作文
Proinsulin is a crucial component in the process of insulin production within the pancreas. It serves as a precursor to insulin, which is a hormone that regulates glucose levels in the blood. The understanding of proinsulin (前胰岛素) is essential for grasping how our bodies manage energy and maintain homeostasis. When we consume food, particularly carbohydrates, our blood sugar levels rise. In response, the pancreas releases proinsulin (前胰岛素), which is then converted into active insulin through a series of enzymatic reactions. This conversion is vital because insulin allows cells in the body to absorb glucose from the bloodstream, thus lowering blood sugar levels. Without this process, our bodies would struggle to utilize energy effectively, leading to conditions such as diabetes. Diabetes is a disease characterized by the body's inability to produce or respond properly to insulin. There are two main types: Type 1 and Type 2 diabetes. In Type 1 diabetes, the immune system attacks the insulin-producing beta cells in the pancreas, leading to a deficiency of insulin. In this case, understanding proinsulin (前胰岛素) is critical, as researchers are exploring ways to protect these cells or replace their function. On the other hand, Type 2 diabetes often involves insulin resistance, where the body produces proinsulin (前胰岛素) but the cells do not respond effectively to it. Over time, the pancreas may become unable to produce enough insulin to meet the body's needs. This situation highlights the importance of maintaining healthy blood sugar levels and the role of proinsulin (前胰岛素) in this balance. Recent research has suggested that measuring levels of proinsulin (前胰岛素) in the blood can provide valuable insights into a person's metabolic state. Elevated levels of proinsulin (前胰岛素) might indicate that the pancreas is working harder to produce insulin due to insulin resistance. This information can help healthcare providers tailor interventions for patients at risk of developing diabetes. In conclusion, proinsulin (前胰岛素) plays a fundamental role in the regulation of blood glucose levels and the overall metabolic health of an individual. Understanding its function not only informs us about the physiological processes involved in energy management but also sheds light on the pathophysiology of diabetes. Ongoing research into proinsulin (前胰岛素) may lead to new therapeutic strategies that could improve the lives of those affected by diabetes and related metabolic disorders. Therefore, recognizing the significance of proinsulin (前胰岛素) is essential for anyone interested in health, nutrition, and medical science.
前胰岛素是胰腺内胰岛素生产过程中一个重要的组成部分。它作为胰岛素的前体,胰岛素是一种调节血糖水平的激素。了解proinsulin(前胰岛素)对于掌握我们身体如何管理能量和维持体内稳态至关重要。当我们摄入食物,特别是碳水化合物时,血糖水平会上升。作为回应,胰腺释放proinsulin(前胰岛素),然后通过一系列酶促反应将其转化为活性胰岛素。这种转化至关重要,因为胰岛素允许身体细胞从血液中吸收葡萄糖,从而降低血糖水平。如果没有这个过程,我们的身体将很难有效利用能量,导致如糖尿病等疾病。糖尿病是一种以身体无法产生或正确响应胰岛素为特征的疾病。主要有两种类型:1型和2型糖尿病。在1型糖尿病中,免疫系统攻击胰腺中的胰岛素生产β细胞,导致胰岛素缺乏。在这种情况下,理解proinsulin(前胰岛素)至关重要,因为研究人员正在探索保护这些细胞或替代其功能的方法。另一方面,2型糖尿病通常涉及胰岛素抵抗,身体产生proinsulin(前胰岛素),但细胞对其反应不佳。随着时间的推移,胰腺可能无法产生足够的胰岛素来满足身体的需求。这种情况突显了保持健康血糖水平的重要性,以及proinsulin(前胰岛素)在这一平衡中的作用。最近的研究表明,测量血液中的proinsulin(前胰岛素)水平可以提供有关一个人代谢状态的有价值见解。升高的proinsulin(前胰岛素)水平可能表明胰腺由于胰岛素抵抗而更努力地生产胰岛素。这些信息可以帮助医疗服务提供者为面临糖尿病风险的患者量身定制干预措施。总之,proinsulin(前胰岛素)在调节血糖水平和个体整体代谢健康方面发挥着基础性作用。理解其功能不仅使我们了解能量管理中的生理过程,还揭示了糖尿病的病理生理学。对proinsulin(前胰岛素)的持续研究可能会导致新的治疗策略,从而改善受糖尿病及相关代谢障碍影响的人的生活。因此,认识到proinsulin(前胰岛素)的重要性对于任何对健康、营养和医学科学感兴趣的人来说都是必不可少的。