cachexia

简明释义

英[kəˈkeksɪə]美[kəˈkeksɪə]

n. [内科] 恶病质；精神萎顿

英英释义

单词用法

同义词

反义词

例句

1.METHODS T739 murine model of cancer cachexia was established to observe the effect of KLT on the cellular immunological function of the mouse.

方法建立T739小鼠癌症恶病质模型，观察KLT对模型鼠细胞免疫功能的作用。

2.Objective to detect the relationship between the serum insulin-like growth factor 1 (IGF-1) level and nutritional status of mice with cancer cachexia.

目的探讨血清中胰岛素样生长因子-1 (IGF - 1)水平与恶病质小鼠营养代谢的关系。

3.Cancer cachexia is a malnutrition syndrome characterized by progressive involuntary weight loss.

肿瘤恶病质是以渐进性的不自主的体重丢失为特征的营养不良综合征。

4.Esophageal cancer; Cachexia; TCM treatment.

食管癌；恶病质；中医治疗。

5.The inflammatory cytokines secreted by host and cachexia specific factor secreted by tumor are the main cause of cachexia.

宿主和肿瘤分泌的炎症因子和恶病质特异因子是引起恶病质的主要原因。

6.Objective To approach the experience of the valve replacement on the patients with rheumatic heart disease complicated cardiac cachexia.

目的探讨风湿性心脏病并发心源性恶液质患者瓣膜置换手术的治疗经验。

7.Objective: To screen the differential expression genes of Kanglaite Injection in treating cancer cachexia.

目的：寻找中药康莱特抗癌症恶病质的表达差异基因。

8.Objective To investigate leptin s mechanism and function in the course of cancer cachexia for matinon in patients suffering from the tumor of peptic system.

目的探讨消化道肿瘤病人血清瘦素在恶液质形成中的可能作用及机制。

9.The team conducted research on the mechanisms behind cachexia 恶病质 in heart failure patients.

研究小组对心力衰竭患者中cachexia 恶病质的机制进行了研究。

10.The patient was diagnosed with cachexia 恶病质 due to advanced cancer.

患者因晚期癌症被诊断为cachexia 恶病质。

11.Weight loss and muscle wasting are common symptoms of cachexia 恶病质.

体重减轻和肌肉萎缩是cachexia 恶病质的常见症状。

12.Doctors often see cachexia 恶病质 in patients with chronic illnesses such as HIV/AIDS.

医生常常在患有慢性疾病如HIV/AIDS的患者中看到cachexia 恶病质。

13.Nutritional support is crucial for managing cachexia 恶病质 in elderly patients.

营养支持对管理老年患者的cachexia 恶病质至关重要。

作文

Cachexia is a complex syndrome characterized by severe weight loss, muscle wasting, and a general decline in health. It is often associated with chronic illnesses such as cancer, AIDS, heart failure, and chronic obstructive pulmonary disease (COPD). The presence of cachexia can significantly impact a patient's quality of life and complicate the management of their underlying disease. Understanding cachexia is essential for healthcare providers to offer effective treatment options and support to affected individuals.The etiology of cachexia is multifactorial, involving a combination of metabolic changes that occur in response to chronic illness. Patients with cachexia often experience an imbalance between energy intake and energy expenditure. This imbalance leads to the depletion of fat stores and skeletal muscle, resulting in significant weight loss. Unlike simple starvation, where the body primarily uses fat stores for energy, cachexia involves the breakdown of muscle tissue, which can lead to weakness and fatigue.One of the primary challenges in managing cachexia is its resistance to conventional nutritional interventions. While patients may be encouraged to increase their caloric intake, this approach often proves ineffective. The underlying metabolic changes associated with cachexia can make it difficult for the body to utilize nutrients effectively. As a result, simply consuming more calories does not always translate into improved health or weight gain.Research has shown that cachexia is driven by inflammatory processes in the body. Cytokines, which are signaling molecules involved in inflammation, play a significant role in the development of cachexia. These cytokines can alter metabolism, promote muscle breakdown, and inhibit appetite, contributing to the overall syndrome. Therefore, addressing the inflammatory components of cachexia may be crucial for effective management.Treatment strategies for cachexia often involve a multidisciplinary approach. This may include pharmacological interventions aimed at reducing inflammation, improving appetite, and enhancing muscle mass. Medications such as corticosteroids, anabolic steroids, and appetite stimulants may be used in conjunction with nutritional support. Additionally, physical therapy and exercise programs can help preserve muscle function and improve overall strength.In conclusion, cachexia is a debilitating condition that poses significant challenges for patients and healthcare providers alike. Its complex nature requires a comprehensive understanding of its underlying mechanisms and a multifaceted approach to treatment. By recognizing the signs and symptoms of cachexia, healthcare professionals can better support patients in managing their condition and improving their quality of life. Ongoing research into the pathophysiology and treatment of cachexia is essential to develop more effective therapies and ultimately enhance patient outcomes.

恶病质是一种复杂的综合征，其特征是严重的体重下降、肌肉消耗和整体健康状况的下降。它通常与癌症、艾滋病、心力衰竭和慢性阻塞性肺病（COPD）等慢性疾病相关。恶病质的存在可以显著影响患者的生活质量，并使其基础疾病的管理变得复杂。理解恶病质对医疗提供者来说至关重要，以便为受影响的个体提供有效的治疗选择和支持。恶病质的病因是多因素的，涉及对慢性疾病反应中发生的代谢变化的组合。患有恶病质的患者通常经历能量摄入与能量消耗之间的不平衡。这种不平衡导致脂肪储备和骨骼肌的耗竭，从而导致显著的体重下降。与简单的饥饿不同，后者主要依靠脂肪储备提供能量，恶病质则涉及肌肉组织的分解，这可能导致虚弱和疲劳。管理恶病质的主要挑战之一是其对传统营养干预的抵抗。尽管鼓励患者增加卡路里摄入，但这种方法往往证明无效。与恶病质相关的基础代谢变化可能使身体难以有效利用营养。因此，单纯增加卡路里的摄入并不总能转化为健康或体重的改善。研究表明，恶病质是由体内炎症过程驱动的。细胞因子，即参与炎症的信号分子，在恶病质的发展中发挥着重要作用。这些细胞因子可以改变代谢，促进肌肉分解，并抑制食欲，从而加剧整体综合征。因此，解决恶病质的炎症成分可能对有效管理至关重要。对恶病质的治疗策略通常涉及多学科的方法。这可能包括旨在减少炎症、改善食欲和增强肌肉质量的药物干预。类固醇、合成代谢类固醇和食欲刺激剂等药物可能与营养支持结合使用。此外，物理治疗和运动计划可以帮助保持肌肉功能并改善整体力量。总之，恶病质是一种使患者和医疗提供者面临重大挑战的虚弱状态。其复杂性需要全面理解其基本机制和多方面的治疗方法。通过识别恶病质的迹象和症状，医疗专业人员可以更好地支持患者管理其病情，提高生活质量。对恶病质的病理生理学和治疗的持续研究对于开发更有效的治疗方案和最终改善患者结果至关重要。