amanitin

简明释义

英[ˌæməˈnaɪtɪn;ˌæməˈniːtɪn]美[əˈmænɪtɪn]

n. 鹅膏蕈碱

英英释义

单词用法

同义词

反义词

例句

1.Amanitin can be detected in the blood almost immediately.

它所产生的蝇蕈素一旦进入血液，可以很快察觉。

2.Amanitin can be detected in the blood almost immediately.

它所产生的蝇蕈素一旦进入血液，可以很快察觉。

3.Symptoms of amanitin poisoning may not appear until several hours after ingestion.

阿曼毒素中毒的症状可能在摄入后几个小时才会出现。

4.Ingesting mushrooms containing amanitin can lead to severe poisoning.

食用含有阿曼毒素的蘑菇可能导致严重中毒。

5.The mechanism of action of amanitin involves inhibiting RNA polymerase II.

阿曼毒素的作用机制涉及抑制RNA聚合酶II。

6.Doctors are concerned about amanitin levels in patients who consume wild mushrooms.

医生担心食用野生蘑菇的患者体内的阿曼毒素水平。

7.The researcher studied the effects of amanitin on liver cells.

研究人员研究了阿曼毒素对肝细胞的影响。

作文

Amanitin is a fascinating and deadly compound that has captured the attention of scientists and medical researchers alike. This potent toxin is derived from the Amanita mushroom, specifically the species known as Amanita phalloides, commonly referred to as the death cap mushroom. The significance of amanitin lies not only in its lethal properties but also in its unique mechanism of action, which has implications for both toxicology and pharmacology.The story of amanitin begins with the discovery of the death cap mushroom, which is notorious for causing fatal poisonings worldwide. When ingested, amanitin disrupts the normal functioning of the liver and kidneys, leading to severe organ failure. It does this by inhibiting RNA polymerase II, an essential enzyme involved in the transcription of DNA into messenger RNA. Without proper transcription, protein synthesis is halted, and cells begin to die, resulting in the devastating effects seen in cases of mushroom poisoning.Despite its toxicity, amanitin has also garnered interest for its potential therapeutic applications. Researchers have been investigating the possibility of using amanitin as a tool in cancer treatment. Its ability to selectively target rapidly dividing cells could be harnessed to develop new cancer therapies. For instance, studies have shown that when modified appropriately, amanitin can be delivered to cancer cells while sparing normal cells, thus minimizing side effects associated with traditional chemotherapy.Moreover, the study of amanitin has provided valuable insights into the mechanisms of gene expression and regulation. By understanding how amanitin interacts with RNA polymerase II, scientists have gained a deeper appreciation of the complexities of cellular processes. This knowledge has far-reaching implications, not only for the development of new drugs but also for our understanding of various diseases, including cancer and genetic disorders.However, the dual nature of amanitin as both a poison and a potential therapeutic agent underscores the importance of careful handling and research. The fine line between its lethal effects and therapeutic benefits necessitates rigorous safety protocols in laboratory settings. Researchers must navigate the challenges of working with such a hazardous substance while striving to unlock its secrets for the betterment of human health.In conclusion, amanitin serves as a poignant reminder of nature's complexity. It embodies the delicate balance between danger and opportunity, illustrating how a single compound can inspire fear and fascination simultaneously. As we continue to explore the depths of amanitin and its effects, we may uncover new pathways for treatment and intervention, ultimately transforming a deadly toxin into a beacon of hope in the fight against disease.

阿曼尼丁是一种迷人而致命的化合物，吸引了科学家和医学研究者的注意。这种强效毒素来源于阿曼塔蘑菇，特别是被称为死亡帽蘑菇的Amanita phalloides。阿曼尼丁的意义不仅在于其致命特性，还在于其独特的作用机制，这对毒理学和药理学都有重要影响。阿曼尼丁的故事始于对死亡帽蘑菇的发现，这种蘑菇因导致全球范围内的致命中毒而臭名昭著。当摄入时，阿曼尼丁会干扰肝脏和肾脏的正常功能，导致严重的器官衰竭。它通过抑制RNA聚合酶II这一关键酶来实现，这种酶参与将DNA转录为信使RNA。没有适当的转录，蛋白质合成就会停止，细胞开始死亡，从而导致蘑菇中毒病例中看到的毁灭性后果。尽管具有毒性，阿曼尼丁也引起了人们对其潜在治疗应用的兴趣。研究人员一直在调查利用阿曼尼丁作为癌症治疗工具的可能性。它选择性靶向快速分裂细胞的能力可以被利用来开发新的癌症疗法。例如，研究表明，当适当修饰时，阿曼尼丁可以被递送到癌细胞，同时保护正常细胞，从而最小化与传统化疗相关的副作用。此外，对阿曼尼丁的研究为基因表达和调控机制提供了宝贵的见解。通过理解阿曼尼丁如何与RNA聚合酶II相互作用，科学家们对细胞过程的复杂性有了更深刻的认识。这一知识具有深远的影响，不仅对新药的开发至关重要，而且对我们理解各种疾病，包括癌症和遗传疾病，也具有重要意义。然而，阿曼尼丁作为一种毒药和潜在治疗剂的双重性质强调了谨慎处理和研究的重要性。其致命效果与治疗益处之间的微妙平衡需要在实验室环境中严格的安全协议。研究人员必须在处理这种危险物质时应对挑战，同时努力揭示其秘密，以改善人类健康。总之，阿曼尼丁是自然复杂性的生动提醒。它体现了危险与机遇之间的微妙平衡，展示了单一化合物如何同时激发恐惧和魅力。随着我们继续探索阿曼尼丁及其影响，我们可能会发现新的治疗和干预途径，最终将一种致命毒素转变为对抗疾病的希望灯塔。