clozapine

简明释义

英[ˈkləʊzəˌpiːn]美[ˈkloʊzəˌpiːn]

n. 氯氮平

英英释义

单词用法

同义词

反义词

例句

1.The effect of clozapine and a antidepressant in the treatment of hypochondriacal neurosis.

氯氮平联用抗抑郁剂治疗疑病症的近期疗效观察。

2.Objective To evaluate the effect of clozapine and a antidepressant in the treatment of hypochondriacal neurosis.

目的评价氯氮平联用抗抑郁剂治疗疑病症的疗效。

3.Results Compared with clozapine group, the score of social function deficiency was lower and that of life quality higher.

结果利培酮组社会功能缺陷评分低于氯氮平组，生活质量评分明显高于氯氮平组。

4.Conclusion Clozapine effectual procedure shows a rule of exponential curve.

结论氯氮平的起效过程呈指数曲线规律。

5.Observention influence of the pulse rate for schizophrenia woman patients with clozapine and risperidone and its nursing.

氯氮平、维思通对女性精神障碍患者脉率影响的观察与护理。

6.Conclusion The effect of clozapine had correlation with the EEG change, slavering and dizziness.

结论氯氮平疗效与脑电图异常、流涎、睡眠增多（包括嗜睡）程度呈反相关系。

7.Conclusion It is an accident of collective food poisoning due to intake of clozapine.

结论这是一起氯氮平引起的集体中毒事件。

8.Green means that it is safe to continue taking your clozapine medication.

绿表示它是安全继续采取氯氮平药物。

9.The psychiatrist prescribed clozapine to help manage the patient's schizophrenia symptoms.

精神科医生开了氯氮平来帮助控制患者的精神分裂症症状。

10.Patients on clozapine need regular blood tests to monitor for potential side effects.

服用氯氮平的患者需要定期进行血液检查，以监测潜在的副作用。

11.After trying several medications, the doctor decided that clozapine was the best option for treatment-resistant schizophrenia.

在尝试了几种药物后，医生决定氯氮平是治疗耐药性精神分裂症的最佳选择。

12.The effectiveness of clozapine in reducing suicidal thoughts has been well documented.

在减少自杀念头方面，氯氮平的有效性已有充分的文献记录。

13.A patient experienced significant improvement in their condition after starting clozapine therapy.

一名患者在开始氯氮平治疗后，病情明显好转。

作文

Clozapine is an antipsychotic medication that is primarily used to treat schizophrenia, particularly in patients who have not responded well to other treatments. It was first introduced in the 1970s and has since become a crucial option for managing treatment-resistant schizophrenia. The mechanism of action of clozapine involves blocking various neurotransmitter receptors in the brain, including dopamine and serotonin receptors. This action helps to reduce symptoms such as hallucinations, delusions, and disorganized thinking, which are common in individuals with schizophrenia. One of the unique aspects of clozapine is its efficacy in patients who have not found relief from other antipsychotic medications. Many patients with treatment-resistant schizophrenia experience significant improvements in their symptoms when prescribed clozapine. However, this medication is not without risks. Patients taking clozapine must be closely monitored for potential side effects, including agranulocytosis, a serious condition that involves a dangerously low white blood cell count. Due to this risk, regular blood tests are required to ensure that the patient’s white blood cell levels remain within a safe range.Moreover, clozapine can also cause other side effects, such as sedation, weight gain, and metabolic syndrome. As a result, healthcare providers often weigh the benefits against the risks when considering clozapine as a treatment option. It is essential for patients to have open discussions with their healthcare providers about their symptoms, treatment goals, and any concerns they may have regarding the use of clozapine.In addition to its use in schizophrenia, research has shown that clozapine may be beneficial for other psychiatric disorders, such as schizoaffective disorder and bipolar disorder. Some studies suggest that clozapine may help reduce suicidal behavior in individuals with these conditions, making it a valuable tool in psychiatric care.The introduction of clozapine into the therapeutic arsenal for schizophrenia has significantly changed the landscape of mental health treatment. Before its availability, many patients with severe forms of schizophrenia had limited options and often faced debilitating symptoms with little hope for improvement. With clozapine, there is a possibility for recovery and better quality of life for those who previously felt trapped by their illness.In conclusion, clozapine represents a vital advancement in the treatment of schizophrenia, especially for those who do not respond to traditional antipsychotics. While it carries certain risks, the potential benefits for patients with treatment-resistant schizophrenia cannot be overlooked. Ongoing research and clinical experience will continue to shed light on the full scope of clozapine's effectiveness and safety, ultimately aiming to enhance the lives of individuals living with this challenging mental health condition.

氯氮平是一种抗精神病药物，主要用于治疗精神分裂症，特别是对其他治疗反应不佳的患者。它于1970年代首次引入，并且自那时以来，已成为管理难治性精神分裂症的重要选择。氯氮平的作用机制涉及阻断大脑中多种神经递质受体，包括多巴胺和血清素受体。这种作用有助于减少幻觉、妄想和思维混乱等症状，这些症状在精神分裂症患者中很常见。氯氮平的一个独特方面是其在未能从其他抗精神病药物中获得缓解的患者中的疗效。许多难治性精神分裂症患者在使用氯氮平时经历了症状的显著改善。然而，这种药物并非没有风险。服用氯氮平的患者必须密切监测潜在的副作用，包括粒细胞缺乏症，这是一种涉及白细胞计数过低的严重情况。因此，定期进行血液检查以确保患者的白细胞水平保持在安全范围内是必要的。此外，氯氮平还可能导致其他副作用，如镇静、体重增加和代谢综合症。因此，医疗提供者在考虑将氯氮平作为治疗选择时，通常会权衡利益与风险。患者与医疗提供者之间就症状、治疗目标及对使用氯氮平的任何担忧进行开放讨论至关重要。除了用于精神分裂症，研究表明氯氮平对其他精神疾病（如情感性精神分裂症和躁郁症）也可能有益。一些研究表明，氯氮平可能有助于减少这些疾病患者的自杀行为，使其成为精神护理中的一种宝贵工具。氯氮平的引入显著改变了精神分裂症治疗的格局。在其可用之前，许多严重形式精神分裂症的患者选择有限，通常面临着令人衰弱的症状，几乎没有改善的希望。通过氯氮平，那些以前感到被疾病困住的患者有了恢复和改善生活质量的可能性。总之，氯氮平代表了治疗精神分裂症的重要进展，尤其是对于那些对传统抗精神病药物无反应的患者。尽管它具有某些风险，但对难治性精神分裂症患者的潜在益处不容忽视。持续的研究和临床经验将继续阐明氯氮平的有效性和安全性的全部范围，最终旨在改善与这种具有挑战性的心理健康状况作斗争的个体的生活。