morphogen

简明释义

英[ˈmɔːfəʊdʒən]美[ˈmɔrfoˌdʒen]

n. 成形素

英英释义

单词用法

同义词

反义词

例句

1.The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research.

本章盖住宽范围有关使感兴趣，从分子基础的成形基因功能那里，令人类遗传学兑一癌症研究的是。

2.The group discovered a morphogen, a protein present in embryonic tissue and encoded by a gene known as Wingless, which seems to be a linchpin of wing decoration.

该小组发现了一种形态形成的机制，有一种存在于胚胎组织中的蛋白被一种称为无翅的基因所确定，这种基因似乎是翅膀装饰的关键基因编码。

3.In Drosophila guttifera, the morphogen ACTS in proximity to existing physical landmarks such as the intersections of veins and cross veins on the wing.

对Drosophila guttifera来说，形态生成是在已有的物理路标附近作用的，如在翅膀的静脉血管与横向静脉的交点处。

4.The role of the Wingless morphogen was detailed by the painstaking genetic manipulation of flies that took three years and the injection of nearly 20,000 fly embryos to accomplish.

无翼基因形态的作用已通过3年艰苦的果蝇基因操作实验与近20,000个果蝇胚胎注射来详细的了解。

5.The role of the Wingless morphogen was detailed by the painstaking genetic manipulation of flies that took three years and the injection of nearly 20, 000 fly embryos to accomplish.

无翼基因形态的作用已通过3年艰苦的果蝇基因操作实验与近20,000个果蝇胚胎注射来详细的了解。

6.The role of the Wingless morphogen was detailed by the painstaking genetic manipulation of flies that took three years and the injection of nearly 20, 000 fly embryos to accomplish.

无翼基因形态的作用已通过3年艰苦的果蝇基因操作实验与近20,000个果蝇胚胎注射来详细的了解。

7.The concentration of the morphogen 形态发生素 determines the type of cells that will develop in a given area.

形态发生素的浓度决定了特定区域内将发展出何种类型的细胞。

8.Scientists are investigating how environmental factors can alter morphogen 形态发生素 signaling pathways.

科学家们正在研究环境因素如何改变形态发生素信号通路。

9.Researchers discovered that a specific morphogen 形态发生素 is crucial for limb formation in vertebrates.

研究人员发现一种特定的形态发生素对脊椎动物的肢体形成至关重要。

10.The study focused on how the morphogen 形态发生素 gradients influence cell differentiation during embryonic development.

这项研究集中在形态发生素梯度如何影响胚胎发育过程中的细胞分化。

11.In tissue engineering, understanding the role of morphogens 形态发生素 can help create more effective scaffolds.

在组织工程中，理解形态发生素的作用可以帮助创建更有效的支架。

作文

In the fascinating field of developmental biology, the term morphogen refers to a substance that governs the pattern of tissue development in the process of morphogenesis. Morphogens are critical signaling molecules that provide spatial and temporal information to cells, guiding them to differentiate into various cell types and organize into complex structures. Understanding how morphogens function is essential for unraveling the mysteries of biological development and has significant implications for regenerative medicine and tissue engineering.During early embryonic development, morphogens play a pivotal role in establishing body plans. For instance, the gradient of a particular morphogen can determine the fate of nearby cells based on their proximity to the source of the signal. Cells that are closer to the source may receive a higher concentration of the morphogen, which can trigger specific gene expression patterns, leading to the formation of distinct tissues and organs. This process is often illustrated by the well-studied example of the Sonic Hedgehog (Shh) protein, a type of morphogen that influences the development of the central nervous system and limbs in vertebrates.Furthermore, morphogens are not only involved in the initial stages of development but also play roles in tissue repair and regeneration. When an organism is injured, the localized release of morphogens can stimulate the surrounding cells to proliferate and differentiate, thereby promoting healing. Researchers are exploring how to harness morphogens to enhance regenerative therapies, particularly for conditions such as spinal cord injuries or degenerative diseases.The study of morphogens also raises intriguing questions about the nature of biological organization. How do cells interpret the concentration gradients of these signaling molecules? What mechanisms ensure that the correct developmental pathways are activated? These questions drive ongoing research in the field, where scientists utilize advanced imaging techniques and genetic manipulation to dissect the roles of various morphogens in living organisms.Moreover, the concept of morphogens extends beyond traditional developmental biology. In recent years, researchers have begun to explore the role of morphogens in cancer biology. Tumor microenvironments often exhibit altered gradients of signaling molecules, which can influence tumor growth and metastasis. By understanding how morphogens function in both normal and pathological contexts, scientists hope to develop targeted therapies that can disrupt these signaling pathways and inhibit cancer progression.In conclusion, the study of morphogens is a rich and evolving area of research that bridges multiple disciplines within biology. From elucidating the fundamental principles of development to addressing pressing medical challenges, morphogens are at the forefront of scientific inquiry. As we continue to uncover the complexities of these signaling molecules, we move closer to unlocking the potential for innovative treatments that harness the power of biological development and regeneration. The exploration of morphogens not only enhances our understanding of life itself but also holds the promise of transforming medicine in the future.

在发育生物学这个迷人的领域中，术语morphogen指的是一种在形态发生过程中控制组织发育模式的物质。morphogen是关键的信号分子，提供空间和时间信息给细胞，引导它们分化成各种细胞类型，并组织成复杂结构。理解morphogen的功能对于揭开生物发育的奥秘至关重要，并对再生医学和组织工程具有重要意义。在早期胚胎发育过程中，morphogen在建立体型计划中发挥着关键作用。例如，特定morphogen的梯度可以根据细胞与信号源的距离决定附近细胞的命运。离信号源较近的细胞可能接收到更高浓度的morphogen，这可以触发特定基因表达模式，从而导致不同组织和器官的形成。这一过程常常通过研究得很好的Sonic Hedgehog（Shh）蛋白的例子来说明，这是一种影响脊椎动物中枢神经系统和肢体发育的morphogen。此外，morphogen不仅参与发育的初始阶段，还在组织修复和再生中发挥作用。当生物体受伤时，局部释放的morphogen可以刺激周围细胞增殖和分化，从而促进愈合。研究人员正在探索如何利用morphogen来增强再生疗法，特别是针对脊髓损伤或退行性疾病等情况。对morphogen的研究还引发了关于生物组织性质的有趣问题。细胞如何解释这些信号分子的浓度梯度？什么机制确保正确的发育路径被激活？这些问题推动了该领域的持续研究，科学家们利用先进的成像技术和基因操作来剖析各种morphogen在活生物体中的作用。此外，morphogen的概念超越了传统的发育生物学。近年来，研究人员开始探索morphogen在癌症生物学中的作用。肿瘤微环境通常表现出改变的信号分子梯度，这可以影响肿瘤的生长和转移。通过理解morphogen在正常和病理背景下的功能，科学家希望开发针对性的治疗方法，以破坏这些信号通路并抑制癌症进展。总之，morphogen的研究是一个丰富且不断发展的研究领域，跨越生物学的多个学科。从阐明发育的基本原理到解决紧迫的医学挑战，morphogen处于科学探究的前沿。随着我们继续揭示这些信号分子的复杂性，我们将更接近于解锁创新治疗的潜力，这些治疗利用生物发育和再生的力量。对morphogen的探索不仅增强了我们对生命本身的理解，还承诺在未来改变医学。