pemphigoid

简明释义

英[ˈpɛm.fɪ.ɡɔɪd]美[ˈpɛm.fɪ.ɡɔɪd]

n. [皮肤] 类天疱疮

adj. [皮肤] 类天疱疮的

英英释义

单词用法

同义词

反义词

例句

1.Autoantibodies in bullous pemphigoid, which is typically a chronic disease, react with 2 hemidesmosomal antigens, bullous pemphigoid180 and bullous pemphigoid.

大疱性类天疱疮是一种慢性病，其自身抗体可以同两种半桥粒抗原反应，大疱性类天疱疮抗原180和大疱性类天疱疮抗原。

2.The research evaluated the effect of Pemphigus and Bullous Pemphigoid on quality of life, at the same time analyzed the relevant factors and the level of awareness of the disease.

本研究评价天疱疮、类天疱疮患者生活质量，探讨影响其生活质量相关因素，了解医患双方对疾病的认知情况。

3.Objective: to investigate the expression of bullous pemphigoid antigen 2 (BPAG2) in different growth stages of hair follicles, and to determine the effects of BPAG2 on hair growth and hair cycles.

目的：研究大疱性类天疱疮抗原2 (BPAG2)在毛发周期不同阶段的表达情况及其对毛发生长和毛发周期的影响。

4.Objective: to investigate the expression of bullous pemphigoid antigen 2 (BPAG2) in different growth stages of hair follicles, and to determine the effects of BPAG2 on hair growth and hair cycles.

目的：研究大疱性类天疱疮抗原2 (BPAG2)在毛发周期不同阶段的表达情况及其对毛发生长和毛发周期的影响。

5.Purpose to investigate the cause of death in aged and old severe patients with autoimmune pemphigus and pemphigoid and to improve the survival rate.

目的探讨中老年自身免疫性天疱疮和类天疱疮患者的死因，提高其生存率。

6.The study is reportedly the first prospective study to assess risk factors related to bullous pemphigoid relapse after cessation of maintenance therapy.

此研究据报道是第一项关于大疱性类天疱疮复发危险因素评价的前瞻性研究。

7.Background. The severity of cicatricial pemphigoid (CP)varies.

瘢痕性类天疱疮（CP）的严重性。

8.In some cases, pemphigoid can lead to serious complications if left untreated.

在某些情况下，如果不治疗，pemphigoid可能会导致严重并发症。

9.Symptoms of pemphigoid include painful blisters and skin erosion.

pemphigoid的症状包括疼痛性水疱和皮肤糜烂。

10.Doctors may perform a biopsy to confirm a diagnosis of pemphigoid.

医生可能会进行活检以确认是否诊断为pemphigoid。

11.The patient was diagnosed with pemphigoid, a rare autoimmune blistering disorder.

患者被诊断为pemphigoid，一种罕见的自身免疫性水疱性疾病。

12.Treatment for pemphigoid often involves corticosteroids to reduce inflammation.

治疗pemphigoid通常涉及使用类固醇来减少炎症。

作文

Pemphigoid is a term used in dermatology to describe a group of rare, autoimmune blistering disorders that primarily affect the skin and mucous membranes. These conditions are characterized by the formation of large, tense blisters that can be quite painful and uncomfortable. The most common types of pemphigoid include bullous pemphigoid, cicatricial pemphigoid, and gestational pemphigoid. Understanding these conditions is essential for both patients and healthcare providers, as they require specific management and treatment approaches.Bullous pemphigoid is the most prevalent form of this disorder, typically occurring in older adults. It is caused by an immune response that mistakenly targets the proteins in the basement membrane of the skin, leading to the separation of the epidermis from the dermis. This results in the formation of blisters that can appear on various parts of the body, including the abdomen, thighs, and arms. Patients often experience intense itching before the blisters develop, which can significantly impact their quality of life.Cicatricial pemphigoid, on the other hand, primarily affects mucous membranes, particularly those in the mouth and eyes. This condition can lead to scarring and complications such as vision loss if left untreated. The immune response in cicatricial pemphigoid targets similar proteins in the basement membrane, but the clinical manifestations differ due to the involvement of mucosal tissues. Early diagnosis and intervention are crucial in managing this type of pemphigoid to prevent long-term damage.Gestational pemphigoid is a rare variant that occurs during pregnancy. It is believed to be related to the hormonal changes and immune adaptations that take place during this period. Although it is generally self-limiting and resolves after delivery, it can cause significant discomfort for the expecting mother. Proper monitoring and supportive care are important to ensure the well-being of both the mother and the baby.The diagnosis of pemphigoid is typically made through a combination of clinical evaluation, histological examination, and serological tests. Skin biopsies can reveal the presence of antibodies against the basement membrane, confirming the autoimmune nature of the disease. Once diagnosed, treatment options may include corticosteroids, immunosuppressive agents, and supportive care to manage symptoms and promote healing.In conclusion, understanding pemphigoid (天疱疮) and its various forms is vital for effective management and treatment. Patients experiencing symptoms such as blistering, itching, or pain should seek medical attention promptly. With appropriate care, many individuals with pemphigoid can lead fulfilling lives despite the challenges posed by these conditions. Awareness and education about pemphigoid are essential in improving outcomes and ensuring that patients receive the support they need to navigate their diagnosis.

天疱疮是皮肤病学中用来描述一组罕见的自身免疫性水疱性疾病的术语，这些疾病主要影响皮肤和粘膜。这些病症的特点是形成大型、紧张的水疱，这些水疱可能非常疼痛和不适。最常见的天疱疮类型包括大疱性天疱疮、瘢痕性天疱疮和妊娠性天疱疮。理解这些疾病对患者和医疗提供者都至关重要，因为它们需要特定的管理和治疗方法。大疱性天疱疮是这种疾病中最常见的形式，通常发生在老年人中。它是由一种免疫反应引起的，该反应错误地针对皮肤基底膜中的蛋白质，导致表皮与真皮的分离。这导致水疱的形成，水疱可以出现在身体的各个部位，包括腹部、大腿和手臂。患者在水疱形成之前通常会经历剧烈的瘙痒，这可能会显著影响他们的生活质量。另一方面，瘢痕性天疱疮主要影响粘膜，特别是口腔和眼睛中的粘膜。这种情况如果不加以治疗，可能导致疤痕和并发症，如视力丧失。瘢痕性天疱疮中的免疫反应针对基底膜中的类似蛋白质，但由于粘膜组织的参与，临床表现有所不同。早期诊断和干预对于管理这种类型的天疱疮至关重要，以防止长期损害。妊娠性天疱疮是一种罕见的变体，发生在怀孕期间。它被认为与此期间发生的激素变化和免疫适应有关。尽管它通常是自限性的，并在分娩后消退，但它可能会给期待的母亲带来显著的不适。适当的监测和支持性护理对于确保母婴的健康至关重要。天疱疮的诊断通常通过临床评估、组织学检查和血清学测试的组合来进行。皮肤活检可以揭示抗体针对基底膜的存在，从而确认该疾病的自身免疫性质。一旦确诊，治疗选择可能包括皮质类固醇、免疫抑制剂和支持性护理，以管理症状并促进愈合。总之，了解pemphigoid（天疱疮）及其各种形式对于有效的管理和治疗至关重要。经历如水疱、瘙痒或疼痛等症状的患者应及时寻求医疗帮助。通过适当的护理，许多患有pemphigoid的人可以尽管面临这些疾病带来的挑战，仍过上充实的生活。提高对pemphigoid的认识和教育对于改善结果和确保患者获得所需支持以应对他们的诊断至关重要。