colchicine

简明释义

英[ˈkɒltʃɪˌsiːn]美[ˈkɑːltʃɪsiːn;ˈkɑːlksiːn]

n. [有化] 秋水仙碱，[有化] 秋水仙素（用番红花作原料而制成的植物盐基）

英英释义

单词用法

同义词

反义词

例句

1.But colchicine is toxic to other tissues in the body, as well as cancer, so until now its use has been limited.

但秋水仙素是有毒物质，在人体的其他组织，以及癌症，所以到现在为止它的使用受到了限制。

2.This indicated that different response existed in some distinct genotypes to chromosome doubling through treating in vitro microspores with colchicine.

由此说明，基因型对秋水仙碱处理离体小孢子诱导染色体加倍的反应不同。

3.The results showed if unripe tuber was harvested, the colchicine content was lower than that of the ripe tuber.

这一结果表明：收获未充分成熟的块茎，会降低秋水仙碱含量。

4.It concludes this method is simple, accurate and reliable, and can be used to control the quality of compound colchicine capsules.

本法简便、准确、可靠，可作为控制复方秋水仙碱胶囊质量标准的方法。

5.Colchicine is a remedy derived from autumn crocus that may be helpful for chronic back pain caused by herniated discs.

秋水仙碱是从秋番红花，可用于慢性背部由椎间盘突出引起的疼痛有帮助得出的补救措施。

6.This is because it contains the potent chemical colchicine, which is known to have medicinal properties, including anti-cancer effects.

这是因为它含有烈性化学秋水仙碱，这是众所周知的药性，包括防癌抗癌作用。

7.A Randomized Trial of Colchicine for Acute Pericarditis.

【译】一种急性心包炎秋水仙碱的随机试验。

8.I read that colchicine can help reduce inflammation in certain conditions.

我读到秋水仙碱可以帮助减少某些病症的炎症。

9.After starting colchicine, my symptoms improved significantly.

开始服用秋水仙碱后，我的症状明显改善。

10.Patients taking colchicine should be monitored for side effects.

服用秋水仙碱的患者应该监测副作用。

11.The doctor prescribed colchicine for my gout flare-up.

医生为我的痛风发作开了秋水仙碱。

12.It’s important to follow the prescribed dosage of colchicine to avoid toxicity.

遵循医生开出的秋水仙碱剂量以避免毒性是很重要的。

作文

Colchicine is a medication that has been used for centuries to treat various ailments, particularly gout and familial Mediterranean fever. Derived from the autumn crocus plant, colchicine is known for its anti-inflammatory properties. The history of this compound dates back to ancient times when it was used in traditional medicine to alleviate pain and inflammation. Today, its application has expanded, and it is recognized as an essential drug in modern medicine. Gout, a type of arthritis characterized by sudden and severe pain, redness, and swelling in the joints, is often caused by the accumulation of uric acid crystals. Colchicine works by inhibiting the inflammatory response triggered by these crystals. When taken during a gout attack, it can significantly reduce the duration and intensity of the symptoms. This makes colchicine a valuable option for patients suffering from this painful condition.In addition to treating gout, colchicine (秋水仙碱) is also effective in managing familial Mediterranean fever, a genetic disorder that leads to recurrent episodes of fever and inflammation. Patients with this condition often experience debilitating symptoms that can affect their quality of life. By using colchicine, they can prevent these episodes and lead a more normal life.The mechanism of action of colchicine involves the disruption of microtubule formation, which plays a crucial role in cell division and inflammation. By preventing the assembly of microtubules, colchicine interferes with the migration of inflammatory cells to the site of injury or inflammation. This results in a decrease in the overall inflammatory response, providing relief to patients.While colchicine is considered safe and effective for many, it is not without side effects. Common side effects include gastrointestinal issues such as diarrhea, nausea, and vomiting. These side effects can be particularly troublesome for some patients, leading to discontinuation of the medication. Therefore, it is essential for healthcare providers to monitor patients closely and adjust dosages as necessary. Moreover, colchicine should be used with caution in individuals with certain health conditions, such as liver or kidney disease. It is also important for patients to inform their doctors about any other medications they are taking, as colchicine can interact with various drugs, potentially leading to harmful effects. Despite these concerns, the benefits of colchicine in managing gout and familial Mediterranean fever cannot be overstated. It remains a cornerstone in the treatment of these conditions and continues to be the subject of research for its potential applications in other inflammatory diseases. For instance, recent studies have explored the role of colchicine in cardiovascular health, particularly in reducing the risk of heart attacks and strokes in patients with chronic inflammatory conditions.In conclusion, colchicine (秋水仙碱) is a remarkable medication that has stood the test of time. Its effectiveness in treating gout and familial Mediterranean fever highlights its importance in modern medicine. As research continues to unveil new uses and benefits, colchicine may play an even more significant role in managing various inflammatory conditions, making it a vital component of therapeutic regimens for patients worldwide.

秋水仙碱是一种已被使用了几个世纪的药物，主要用于治疗各种疾病，特别是痛风和家族性地中海热。它来源于秋季番红花植物，以其抗炎特性而闻名。这种化合物的历史可以追溯到古代，当时它被用于传统医学来缓解疼痛和炎症。如今，它的应用已扩大，并在现代医学中被认可为一种重要药物。痛风是一种关节炎，特征是关节突然出现剧烈疼痛、发红和肿胀，通常是由于尿酸结晶的积累引起的。colchicine（秋水仙碱）通过抑制由这些结晶引发的炎症反应来发挥作用。在痛风发作期间服用colchicine可以显著减少症状的持续时间和强度，这使得colchicine成为痛风患者的宝贵选择。除了治疗痛风外，colchicine（秋水仙碱）在管理家族性地中海热方面也很有效，这是一种导致反复发作的发热和炎症的遗传性疾病。患有这种疾病的患者经常经历严重的症状，这可能会影响他们的生活质量。通过使用colchicine，他们可以预防这些发作，过上更正常的生活。colchicine（秋水仙碱）的作用机制涉及微管形成的干扰，而微管在细胞分裂和炎症中发挥着至关重要的作用。通过阻止微管的组装，colchicine（秋水仙碱）干扰了炎症细胞向损伤或炎症部位的迁移，从而导致整体炎症反应的减少，为患者提供了缓解。尽管colchicine（秋水仙碱）被认为对许多人是安全有效的，但它并非没有副作用。常见的副作用包括胃肠道问题，如腹泻、恶心和呕吐。这些副作用对于某些患者来说可能特别麻烦，导致停止使用该药物。因此，医疗提供者密切监测患者并根据需要调整剂量至关重要。此外，colchicine（秋水仙碱）在某些健康状况下应谨慎使用，例如肝脏或肾脏疾病。患者还应告知医生他们正在服用的任何其他药物，因为colchicine（秋水仙碱）可能与各种药物相互作用，可能导致有害效果。尽管有这些顾虑，但colchicine（秋水仙碱）在管理痛风和家族性地中海热方面的益处不可低估。它仍然是这些疾病治疗的基石，并继续成为研究的主题，以探索其在其他炎症性疾病中的潜在应用。例如，最近的研究探讨了colchicine（秋水仙碱）在心血管健康中的作用，特别是在降低慢性炎症疾病患者心脏病发作和中风风险方面。总之，colchicine（秋水仙碱）是一种卓越的药物，经过时间的考验。它在治疗痛风和家族性地中海热方面的有效性突显了它在现代医学中的重要性。随着研究继续揭示新的用途和益处，colchicine（秋水仙碱）可能在管理各种炎症性疾病中发挥更重要的作用，使其成为全球患者治疗方案的重要组成部分。