indomethacin

简明释义

英[ɪndəʊˈmeθəsɪn]美[ˌɪndoʊˈmeθəsɪn]

n. [药] 消炎痛；茚甲新

英英释义

单词用法

同义词

反义词

例句

1.In recent years clinical studies indicated that indomethacin had therapeutical effect on dysmenorrhea, the pains of operation, acesodyne of tumor.

近年来的研究和临床实践发现吲哚美辛还可用于痛经症状的缓解、手术后疼痛和肿瘤止痛的阶梯治疗。

2.Objective To study the preparation process and quality control method of indomethacin liniment.

目的探讨吲哚美辛搽剂的制备及质量控制标准。

3.According to the thermodynamic parameters, the main acting force between indomethacin and HSA was determined.

根据热力学常数确定了它们之间的主要作用力类型。

4.Objective:To study the protective effect of Weishusan on small intestinal lesions induced by indomethacin in rats.

目的：研究胃舒散对消炎痛所致大鼠小肠损伤的保护作用及机制。

5.Aim: To investigate the effects of indomethacin (im) on free radical reactions in brain tissues of rabbits with acute experimental brain injury.

目的：探讨消炎痛对急性实验性脑外伤后兔脑组织氧自由基反应的影响。

6.OBJECTIVES: To prepare indomethacin enteric-coated pellets and investigate their release properties.

目的：制备吲哚美辛肠溶包衣徽丸，考察其释放特性。

7.Treatment with potassium, indomethacin, and GH has been effective.

应用钾、吲哚美辛、GH治疗是有效的。

8.Then we collect the blood in different time point and assay the blood concentration of indomethacin by RP-HPLC.

于不同时间点取血，以反相高效液相色谱法测定吲哚美辛的血药浓度。

9.The results showed that 0.5% indomethacin oil drops were worth being used for prevention of electric photophthalmia.

实验结果提示，0.5%消炎痛油剂在电光性眼炎防治方面有应用价值。

10.After taking indomethacin, the swelling in her knee significantly reduced.

服用吲哚美辛后，她膝盖的肿胀明显减轻。

11.The doctor prescribed indomethacin for the patient's severe arthritis pain.

医生为患者的严重关节炎疼痛开了吲哚美辛。

12.Some side effects of indomethacin include headache and dizziness.

吲哚美辛的一些副作用包括头痛和头晕。

13.Patients are advised to take indomethacin with food to minimize gastrointestinal discomfort.

建议患者与食物一起服用吲哚美辛以减少胃肠不适。

14.The effectiveness of indomethacin in treating gout has been well documented.

吲哚美辛在治疗痛风方面的有效性已有充分记录。

作文

Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), is commonly used to treat various conditions characterized by inflammation and pain. This medication is particularly effective for conditions such as arthritis, gout, and other inflammatory disorders. The mechanism of action of indomethacin involves the inhibition of cyclooxygenase (COX) enzymes, which play a crucial role in the production of prostaglandins. Prostaglandins are compounds that promote inflammation, pain, and fever; thus, by blocking their synthesis, indomethacin helps alleviate these symptoms.The use of indomethacin dates back to the 1960s when it was first introduced as an effective treatment option for rheumatoid arthritis. Over the years, its application has expanded to include various forms of arthritis, such as osteoarthritis and ankylosing spondylitis. Additionally, indomethacin is often prescribed for acute gout attacks due to its potent anti-inflammatory properties.Patients taking indomethacin should be aware of potential side effects, which can include gastrointestinal issues, headaches, dizziness, and, in some cases, cardiovascular problems. It is essential for patients to discuss their medical history with their healthcare provider before starting indomethacin. This is particularly important for individuals with a history of stomach ulcers or bleeding, as NSAIDs can exacerbate these conditions.Moreover, while indomethacin is effective in managing pain and inflammation, it is not without risks. Long-term use of this medication may lead to kidney damage or increased blood pressure. Therefore, regular monitoring by a healthcare professional is recommended for patients on prolonged therapy with indomethacin.In addition to its oral formulation, indomethacin is available in rectal suppositories and topical formulations, providing flexibility in administration based on patient needs. The choice of formulation may depend on the severity of the condition and the patient's ability to tolerate oral medications.It is vital for patients to follow the prescribed dosage and schedule to minimize the risk of adverse effects associated with indomethacin. If a dose is missed, patients should take it as soon as they remember but avoid doubling up on doses. Furthermore, patients should not abruptly discontinue indomethacin without consulting their doctor, especially if they have been on the medication for an extended period.In conclusion, indomethacin is a valuable medication in the management of inflammatory conditions. Its effectiveness in reducing pain and inflammation makes it a go-to choice for many healthcare providers. However, like all medications, it carries potential risks that must be weighed against its benefits. Patients should engage in open communication with their healthcare team to ensure safe and effective use of indomethacin in their treatment regimen.

吲哚美辛是一种非甾体抗炎药（NSAID），通常用于治疗各种以炎症和疼痛为特征的疾病。这种药物对关节炎、痛风和其他炎症性疾病等情况特别有效。吲哚美辛的作用机制涉及抑制环氧合酶（COX）酶，这些酶在前列腺素的产生中发挥着关键作用。前列腺素是促进炎症、疼痛和发热的化合物；因此，通过阻止它们的合成，吲哚美辛有助于缓解这些症状。吲哚美辛的使用可以追溯到20世纪60年代，当时它首次被引入作为类风湿关节炎的有效治疗选择。多年来，它的应用扩展到包括各种形式的关节炎，如骨关节炎和强直性脊柱炎。此外，由于其强效抗炎特性，吲哚美辛通常用于急性痛风发作的治疗。服用吲哚美辛的患者应注意潜在的副作用，包括胃肠问题、头痛、头晕以及在某些情况下的心血管问题。在开始使用吲哚美辛之前，患者与医疗提供者讨论他们的病史至关重要。这对于有胃溃疡或出血史的人尤其重要，因为NSAID可能加重这些病症。此外，虽然吲哚美辛在管理疼痛和炎症方面有效，但并非没有风险。长期使用这种药物可能导致肾损伤或血压升高。因此，建议在长期使用吲哚美辛的患者中定期进行医疗监测。除了口服制剂外，吲哚美辛还可提供栓剂和局部制剂，根据患者的需求提供灵活的给药选择。制剂的选择可能取决于疾病的严重程度和患者耐受口服药物的能力。患者遵循处方剂量和时间表以最小化与吲哚美辛相关的不良反应风险至关重要。如果错过了一剂，患者应尽快服用，但要避免重复服用。此外，患者在长时间使用吲哚美辛后不应在未咨询医生的情况下突然停药。总之，吲哚美辛是管理炎症性疾病的宝贵药物。其在减轻疼痛和炎症方面的效果使其成为许多医疗提供者的首选。然而，像所有药物一样，它也带有潜在风险，必须权衡其利弊。患者应与其医疗团队进行开放的沟通，以确保在治疗方案中安全有效地使用吲哚美辛。