intrathecally

简明释义

英[ˌɪntrəˈθiːkli]美[ˌɪntrəˈθiːkli]

鞘内注射

英英释义

单词用法

同义词

反义词

例句

1.Pregabalin was administered either intraperitoneally (IP) or intrathecally (IT) and dosed up incrementally until an antiallodynic effect without sedation or motor impairment was apparent.

普瑞巴林通过腹膜内或鞘内给药剂量逐渐增加直到产生抗痛觉超敏作用或出现运动受损。

2.Methods: Experimental rats were intrathecally injected with carbenoxolone(CBX), a special gap junction blocker, and the control rats with the saline.

方法：向实验组大鼠鞘内注射一种缝隙连接的阻断剂甘珀酸；

3.Experimental rats were intrathecally injected with carbenoxolone, a special gap junction blocker, and the control rats with the saline.

给实验大鼠鞘内注射羧苄索龙（一种特殊的间隙连接阻滞剂），向对照组大鼠注射生理盐水。

4.Pregabalin was administered either intraperitoneally (IP) or intrathecally (IT) and dosed up incrementally until an antiallodynic effect without sedation or motor impairment was apparent.

普瑞巴林通过腹膜内或鞘内给药剂量逐渐增加直到产生抗痛觉超敏作用或出现运动受损。

5.For chronic pain management, some physicians opt for intrathecally implanted drug delivery systems.

对于慢性疼痛管理，一些医生选择使用鞘内植入药物输送系统。

6.Doctors often use intrathecally delivered chemotherapy for certain types of cancer.

医生通常对某些类型的癌症使用鞘内给药的化疗。

7.In cases of severe spinal pain, a doctor may recommend an intrathecally injected analgesic.

在严重脊柱疼痛的情况下，医生可能会建议注射鞘内止痛药。

8.The medication was administered intrathecally to ensure rapid pain relief.

药物通过鞘内给药，以确保快速缓解疼痛。

9.The patient received a vaccine intrathecally to enhance its effectiveness against meningitis.

患者通过鞘内接种疫苗，以增强其对脑膜炎的有效性。

作文

In the field of medicine, the term intrathecally refers to a method of delivering medication directly into the spinal canal. This technique is particularly significant in the treatment of certain neurological conditions and chronic pain management. By administering drugs intrathecally, healthcare professionals can achieve higher concentrations of medication at the site of action while minimizing systemic side effects. For instance, opioids are often used intrathecally to provide relief from severe pain that does not respond to conventional oral or intravenous therapies.The process of intrathecally administering medication typically involves a lumbar puncture, where a needle is inserted into the lower back to access the cerebrospinal fluid (CSF). This allows for the precise delivery of drugs directly into the CSF, which surrounds the spinal cord and brain. The advantage of this route is that it bypasses the blood-brain barrier, enabling medications that might not be effective if taken orally to exert their effects directly on the central nervous system.One of the most common applications of intrathecally delivered medications is in the treatment of spasticity, a condition characterized by excessive muscle tone and stiffness. Patients suffering from multiple sclerosis or spinal cord injuries often experience debilitating spasticity that can significantly impact their quality of life. By using baclofen, a muscle relaxant, intrathecally, physicians can target the spinal pathways involved in muscle contraction, providing much-needed relief.Moreover, intrathecally administered chemotherapy has emerged as a promising approach for treating certain types of cancers that affect the central nervous system, such as leptomeningeal carcinomatosis. This condition occurs when cancer cells spread to the membranes surrounding the brain and spinal cord. By delivering chemotherapeutic agents intrathecally, doctors can achieve higher local concentrations of the drug, potentially improving treatment outcomes while reducing exposure to other organs.However, the intrathecal administration of medication is not without risks. Complications such as infection, bleeding, and nerve damage can occur, making it essential for healthcare providers to carefully evaluate the benefits and risks before proceeding with this treatment option. Additionally, patients must be monitored closely following intrathecally administered treatments to manage any adverse effects and ensure the desired therapeutic outcomes.In conclusion, the term intrathecally plays a crucial role in modern medical practices, especially in neurology and pain management. The ability to deliver medications directly to the central nervous system opens up new avenues for treating conditions that were once difficult to manage. As research continues to advance our understanding of intrathecally administered therapies, we can expect to see even more innovative approaches to patient care in the future. Understanding the implications and applications of intrathecally is essential for both healthcare professionals and patients alike, as it highlights the evolving landscape of medical treatment options available today.

在医学领域，术语intrathecally指的是一种将药物直接输送到脊髓腔的方法。这种技术在某些神经系统疾病和慢性疼痛管理的治疗中尤为重要。通过intrathecally给药，医疗专业人员可以在减少全身副作用的同时，在作用部位实现更高浓度的药物。例如，阿片类药物通常用于intrathecally缓解严重的疼痛，这种疼痛对常规的口服或静脉治疗无反应。intrathecally给药的过程通常涉及腰椎穿刺，即将针头插入下背部以进入脑脊液（CSF）。这允许将药物精确地直接输送到脑脊液中，脑脊液包围着脊髓和大脑。这种途径的优势在于它绕过了血脑屏障，使得那些如果口服可能无效的药物能够直接对中枢神经系统产生作用。intrathecally给药的一种常见应用是治疗痉挛症，这是一种以肌肉张力和僵硬过度为特征的病症。患有多发性硬化症或脊髓损伤的患者常常经历严重的痉挛，这会显著影响他们的生活质量。通过使用巴克洛芬（一种肌肉松弛剂）intrathecally，医生可以针对参与肌肉收缩的脊髓通路，从而提供急需的缓解。此外，intrathecally给药的化疗也成为治疗某些影响中枢神经系统的癌症（如脑膜癌转移）的有前景的方法。当癌细胞扩散到大脑和脊髓周围的膜时，就会发生这种情况。通过intrathecally输送化疗药物，医生可以实现更高的局部药物浓度，潜在地改善治疗效果，同时减少对其他器官的暴露。然而，intrathecally给药并非没有风险。可能出现感染、出血和神经损伤等并发症，因此医疗提供者在进行此治疗选项之前必须仔细评估利弊。此外，患者在接受intrathecally给药治疗后必须密切监测，以管理任何不良反应并确保期望的治疗效果。总之，术语intrathecally在现代医疗实践中扮演着至关重要的角色，尤其是在神经学和疼痛管理领域。将药物直接输送到中枢神经系统的能力为治疗曾经难以管理的疾病开辟了新的途径。随着研究不断推进我们对intrathecally给药疗法的理解，我们可以期待未来在患者护理方面看到更多创新的方法。理解intrathecally的含义和应用对于医疗专业人员和患者来说都至关重要，因为它突显了当今可用医疗治疗选择的不断发展格局。