alloantigen

简明释义

英[ˌæləʊˈæntɪdʒən]美[ˌæloˈæntɪdʒən]

n. [免疫] 同种抗原；异体抗原

英英释义

单词用法

同义词

反义词

例句

1.Conclusion Oral administration of alloantigen can down-regulate the immune response to histocompatibility antigens, prolong the survival times of heart allografts.

结论：口服抗原可以引起受者对异基因抗原的特异性免疫反应降低，使受者的心脏移植存活期延长。

2.Antibodies respond to the quaternary structure of proteins so their potential to cross-react with an alloantigen is very low.

抗体对蛋白质的四级结构产生应答，因此它们对同种异型抗原发生交叉反应的能力较弱。

3.Objective To establish the method of alloantigen specific t lymphocyte clones.

目的建立抗原特异性T淋巴细胞克隆的方法。

4.Conclusion Oral administration of alloantigen can down-regulate the immune response to histocompatibility antigens, prolong the survival times of heart allografts.

结论：口服抗原可以引起受者对异基因抗原的特异性免疫反应降低，使受者的心脏移植存活期延长。

5.In pregnancy, a mother’s immune system may tolerate the fetus due to the presence of paternal alloantigens (异种抗原).

在怀孕期间，母亲的免疫系统可能会因父亲的alloantigens（异种抗原）的存在而对胎儿产生耐受。

6.Blood transfusions require careful matching to avoid reactions against alloantigens (异种抗原) present in donor blood.

输血需要仔细匹配，以避免对供体血液中存在的alloantigens（异种抗原）产生反应。

7.The identification of specific alloantigens (异种抗原) can help predict transplant rejection.

特定alloantigens（异种抗原）的识别可以帮助预测移植排斥反应。

8.The immune response can be triggered by the presence of an alloantigen (异种抗原) during organ transplantation.

器官移植过程中，alloantigen（异种抗原）的存在可以引发免疫反应。

9.Research on alloantigens (异种抗原) is crucial for developing better immunosuppressive therapies.

对alloantigens（异种抗原）的研究对开发更好的免疫抑制疗法至关重要。

作文

In the field of immunology, the term alloantigen refers to an antigen that is present in some individuals of a species but absent in others. This concept is crucial for understanding how the immune system recognizes and responds to foreign substances. For instance, when a person receives a blood transfusion or an organ transplant, their immune system may react against the donor's alloantigen, leading to potential complications. The body recognizes these foreign alloantigens as threats, triggering an immune response that can result in rejection of the transplanted tissue or blood. One of the most well-known examples of alloantigen is the ABO blood group system. Each person has specific antigens on the surface of their red blood cells, which determine their blood type. If a person with type A blood receives type B blood, their immune system will identify the B antigens as foreign alloantigens and mount an attack against them. This can lead to hemolytic reactions, which can be life-threatening. Therefore, understanding alloantigens is essential for ensuring compatibility in blood transfusions and organ transplants.Moreover, alloantigens play a significant role in autoimmune diseases as well. In some cases, the immune system mistakenly identifies the body’s own proteins as foreign alloantigens, leading to an autoimmune response. Conditions such as rheumatoid arthritis and lupus are examples where the body’s immune system attacks its own tissues, mistaking them for harmful invaders due to similarities with foreign alloantigens. Research into alloantigens is ongoing, particularly in the context of transplantation. Scientists are exploring ways to manipulate the immune response to minimize rejection. One approach is through the use of immunosuppressive drugs that dampen the immune response, allowing the body to accept the transplanted organ without attacking the alloantigens present on its surface. Another strategy involves gene editing technologies like CRISPR, which could potentially modify the alloantigens expressed by donor organs to make them more compatible with the recipient's immune system.In conclusion, the concept of alloantigen is fundamental in immunology, especially concerning blood transfusions and organ transplants. Understanding how alloantigens function and interact with the immune system is vital for improving medical procedures and patient outcomes. As research continues to advance, we may find new ways to manage and mitigate the effects of alloantigens in various medical contexts, ultimately leading to safer and more effective treatments for patients in need of transfusions or transplants. The study of alloantigens not only enhances our understanding of the immune system but also opens up new avenues for therapeutic interventions, providing hope for countless individuals facing challenges related to immune responses.

在免疫学领域，术语alloantigen指的是在某些个体中存在但在其他个体中缺失的一种抗原。这个概念对于理解免疫系统如何识别和应对外来物质至关重要。例如，当一个人接受输血或器官移植时，他们的免疫系统可能会对供体的alloantigen产生反应，导致潜在的并发症。身体将这些外来的alloantigens视为威胁，触发免疫反应，从而可能导致移植组织或血液的排斥。最著名的alloantigen例子之一是ABO血型系统。每个人的红细胞表面都有特定的抗原，这决定了他们的血型。如果一个A型血的人接受B型血，他们的免疫系统会将B抗原识别为外来alloantigen并对其发起攻击。这可能导致溶血反应，甚至危及生命。因此，理解alloantigens对于确保输血和器官移植的兼容性至关重要。此外，alloantigens在自身免疫疾病中也发挥着重要作用。在某些情况下，免疫系统错误地将身体自身的蛋白质识别为外来alloantigens，导致自身免疫反应。类风湿性关节炎和狼疮等疾病就是一些例子，其中身体的免疫系统攻击自身组织，将其误认为有害的入侵者，因为与外来alloantigens相似。关于alloantigens的研究正在进行中，特别是在移植背景下。科学家们正在探索操控免疫反应以最小化排斥的方法。一种方法是使用免疫抑制药物来减弱免疫反应，使身体能够接受移植的器官而不攻击其表面的alloantigens。另一种策略涉及基因编辑技术，如CRISPR，可能会修改供体器官表达的alloantigens，使其与受体的免疫系统更兼容。总之，alloantigen的概念在免疫学中是基础性的，尤其是在输血和器官移植方面。理解alloantigens如何与免疫系统相互作用对于改善医疗程序和患者结果至关重要。随着研究的不断进展，我们可能会找到新的方法来管理和减轻各种医疗背景下alloantigens的影响，最终为需要输血或移植的患者提供更安全、更有效的治疗。对alloantigens的研究不仅增强了我们对免疫系统的理解，还为治疗干预开辟了新的途径，为无数面临免疫反应挑战的个人带来了希望。