hyalinization

简明释义

英[ˌhaɪəlɪnaɪˈzeɪʃən]美[ˌhaɪələnəˈzeɪʃən]

n. 透明样变化

英英释义

单词用法

同义词

反义词

例句

1.This islet of Langerhans demonstrates pink hyalinization (with deposition of amyloid) in many of the islet cells.

在胰岛的胰腺细胞内可见粉红色的透明变性（淀粉样物质沉积）。

2.Areas of stromal hyalinization, adenofibromatous growth, and psammoma bodies were present in a minority of cases.

少数病例可出现间质玻璃样变区、腺纤维瘤样结构和砂粒体。

3.Areas of stromal hyalinization, adenofibromatous growth, and psammoma bodies were present in a minority of cases.

少数病例可出现间质玻璃样变区、腺纤维瘤样结构和砂粒体。

4.The pathologist noted significant hyalinization in the tissue samples, indicating a possible degenerative process.

病理学家注意到组织样本中显著的透明化，这表明可能存在退行性过程。

5.In chronic inflammation, hyalinization can lead to the formation of fibrous tissue.

在慢性炎症中，透明化可能导致纤维组织的形成。

6.The presence of hyalinization in the kidney biopsies suggested advanced disease.

肾活检中出现的透明化提示疾病已进展到晚期。

7.During the examination, the doctor explained that hyalinization could affect organ function.

在检查过程中，医生解释说透明化可能会影响器官功能。

8.The research focused on the mechanisms behind hyalinization in lung tissues.

这项研究集中于肺组织中透明化的机制。

作文

Hyalinization is a term often encountered in the fields of histology and pathology. It refers to a process where tissues undergo a transformation into a glassy, translucent appearance due to the accumulation of proteins and other substances. This phenomenon can be observed in various medical conditions, particularly in chronic diseases. Understanding the implications of hyalinization is crucial for both diagnosis and treatment strategies. In histological studies, hyalinization is typically seen in kidney tissues affected by chronic conditions such as hypertension or diabetes mellitus. The glomeruli, which are the filtering units of the kidneys, may become sclerotic and exhibit this glassy appearance. This change indicates a loss of function and can lead to renal failure if not addressed promptly. Similarly, in the lungs, hyalinization can occur in cases of pulmonary fibrosis, where lung tissue becomes stiff and less capable of gas exchange.The mechanisms behind hyalinization involve the deposition of extracellular matrix components, such as collagen and fibrin, which replace normal tissue architecture. This process is often a response to injury or inflammation, where the body attempts to heal itself but, in doing so, creates an abnormal tissue structure. For instance, in the liver, chronic alcohol abuse can lead to hyalinization of hepatocytes, resulting in cirrhosis, a condition characterized by scarring and impaired liver function.From a clinical perspective, recognizing hyalinization is vital for pathologists examining biopsies. The presence of hyaline deposits can provide clues about the underlying disease process and help guide further investigations. For example, in the context of rheumatoid arthritis, hyalinization of joint tissues may indicate chronic inflammation and damage, leading to joint deformities over time.Moreover, hyalinization can also be a feature of certain neoplasms, where tumor cells may induce a hyaline change in surrounding stroma. This can complicate the interpretation of tumor margins and affect surgical planning. Therefore, understanding the context in which hyalinization occurs is essential for accurate diagnosis and effective treatment.In summary, hyalinization is a significant histopathological phenomenon that reflects underlying pathological processes in various tissues. Its identification can aid in diagnosing chronic diseases and understanding their progression. As research continues to advance, it is hoped that further insights into the mechanisms of hyalinization will lead to improved therapeutic approaches and better patient outcomes.

透明化是一个在组织学和病理学领域常见的术语。它指的是组织因蛋白质和其他物质的积累而发生转变，呈现出玻璃状、半透明的外观。这种现象可以在各种医学条件中观察到，尤其是在慢性疾病中。理解透明化的含义对于诊断和治疗策略至关重要。在组织学研究中，透明化通常出现在受慢性病影响的肾脏组织中，例如高血压或糖尿病。肾小球，即肾脏的过滤单位，可能变得硬化并表现出这种玻璃状外观。这种变化表明功能丧失，如果不及时处理，可能导致肾功能衰竭。同样，在肺部，透明化可能发生在肺纤维化的情况下，肺组织变得僵硬，气体交换能力下降。透明化背后的机制涉及细胞外基质成分的沉积，例如胶原蛋白和纤维蛋白，这些成分取代了正常的组织结构。这个过程通常是对损伤或炎症的反应，身体试图自我修复，但在这样做时又创造了异常的组织结构。例如，在肝脏中，慢性酗酒可能导致肝细胞的透明化，最终导致肝硬化，这是一种以疤痕和肝功能障碍为特征的疾病。从临床角度来看，识别透明化对病理学家检查活检样本至关重要。透明沉积的存在可以提供关于潜在疾病过程的线索，并帮助指导进一步的检查。例如，在类风湿性关节炎的背景下，关节组织的透明化可能表明慢性炎症和损伤，随着时间的推移导致关节畸形。此外，透明化也可能是某些肿瘤的特征，其中肿瘤细胞可能诱导周围基质的透明变化。这可能会使肿瘤边缘的解读变得复杂，并影响外科手术的计划。因此，理解透明化发生的背景对于准确诊断和有效治疗至关重要。总之，透明化是一个重要的组织病理现象，反映了各种组织中潜在的病理过程。它的识别可以帮助诊断慢性疾病并理解其进展。随着研究的不断推进，希望对透明化机制的进一步了解将导致改进治疗方法和更好的患者结果。