repressor

简明释义

英[rɪˈpresə(r)]美[rɪˈpresər]

n. 阻抑物；阻遏蛋白；镇压者

英英释义

单词用法

同义词

反义词

例句

1.Surprisingly, the factor turns out to have been previously characterized as a general repressor of transcription, NC2, an observation explained by its ability to repress TATA-box-containing promoters.

另人吃惊的是，这个因子证明是具有一般转录抑制因子nc2的明显的特征。

2.Some new type of two-hybrid systems, such as split-ubiquitin system, protein-fragment complementation assay, repressor reconstitution assay and SOS recruitment system, have been developed recently.

前言： 近年来，一些不依赖于转录因子活性的新型双杂交系统相继建立，如分离的泛素系统、 蛋白质片段互补分析、阻遏物重构分析和SOS恢复系统等。

3.The repressor is essentially a negative control mechanism.

阻遏物基本上是一种负控制机制。

4.The repressor is essentially a negative control mechanism .

阻遏物基本上是一种负控制机制。

5.Surprisingly, the factor turns out to have been previously characterized as a general repressor of transcription, NC2, an observation explained by its ability to repress TATA-box-containing promoters.

另人吃惊的是，这个因子证明是具有一般转录抑制因子nc2的明显的特征。

6.The newly identified repressor switch could provide part of the answer.

他们新近确认的抑制剂转化可以部分解答这个问题。

7.Church recalls seeing plasmid and gene sequences for the first time-penicillinase and insulin, the lac repressor and interferon.

Church回忆第一次见到了质粒和基因序列的情形-青霉素酶和胰岛素，阻遏物和干扰素。

8.Researchers have identified a new repressor that plays a crucial role in cancer cell growth.

研究人员发现了一种新的抑制子，在癌细胞生长中起着关键作用。

9.The gene expression is controlled by a specific repressor, which binds to the DNA and prevents transcription.

基因表达由一个特定的抑制子控制，它与DNA结合并阻止转录。

10.Mutations in the repressor gene can lead to uncontrolled cell division.

在抑制子基因中的突变可能导致细胞分裂失控。

11.The repressor works by blocking the RNA polymerase from accessing the promoter region.

该抑制子通过阻止RNA聚合酶访问启动子区域来工作。

12.In bacteria, the repressor protein can inhibit the production of enzymes when certain nutrients are abundant.

在细菌中，当某些营养物质丰富时，抑制子蛋白可以抑制酶的产生。

作文

In the field of molecular biology, a significant concept is that of the repressor (抑制子), which plays a crucial role in gene regulation. Understanding how repressors function can provide insights into various biological processes, including development, cellular differentiation, and responses to environmental changes. A repressor is a type of protein that binds to specific DNA sequences, thereby inhibiting the transcription of genes. This mechanism is essential for controlling when and where genes are expressed within an organism.The operation of a repressor is often compared to a switch that turns off the expression of certain genes. For instance, in the classic example of the lac operon in E. coli, the presence of lactose leads to the inactivation of the repressor. When lactose is available, it binds to the repressor, causing a conformational change that prevents the repressor from binding to the operator region of the operon. As a result, RNA polymerase can access the promoter and initiate transcription of the genes needed for lactose metabolism.The importance of repressors extends beyond prokaryotic systems. In eukaryotes, repressors are also involved in complex regulatory networks that control gene expression during various stages of development. For example, in the process of embryonic development, specific repressors ensure that genes are turned off at the right times, allowing cells to differentiate into various types. Any malfunction or misregulation of these repressors can lead to developmental disorders or diseases such as cancer.Moreover, the study of repressors has significant implications for biotechnology and medicine. By understanding how repressors work, scientists can develop targeted therapies that modulate gene expression in specific cells. For instance, if a particular repressor is found to be overactive in a cancer cell, researchers might design drugs that inhibit its activity, thereby reactivating tumor-suppressor genes that have been silenced. This approach highlights the potential of manipulating repressors for therapeutic purposes.In conclusion, the concept of the repressor (抑制子) is fundamental to our understanding of gene regulation in both prokaryotic and eukaryotic organisms. The ability of repressors to control gene expression is essential for maintaining cellular homeostasis and enabling proper development. As research continues to uncover the intricacies of gene regulation, the role of repressors will undoubtedly remain a key focus, offering exciting opportunities for advancements in biotechnology and medicine.

在分子生物学领域，一个重要的概念是repressor（抑制子），它在基因调控中起着至关重要的作用。理解repressor的功能可以为各种生物过程提供见解，包括发育、细胞分化和对环境变化的反应。repressor是一种结合特定DNA序列的蛋白质，从而抑制基因的转录。这一机制对于控制基因在生物体内何时以及在哪里被表达至关重要。repressor的运作通常被比作一个开关，关闭某些基因的表达。例如，在大肠杆菌的经典例子——乳糖操纵子中，乳糖的存在导致repressor失活。当乳糖可用时，它会与repressor结合，导致构象变化，使得repressor无法结合到操纵子的操作区。因此，RNA聚合酶可以接触到启动子并启动需要进行乳糖代谢的基因的转录。repressor的重要性超越了原核系统。在真核生物中，repressor也参与复杂的调控网络，控制基因在不同发育阶段的表达。例如，在胚胎发育过程中，特定的repressor确保基因在正确的时间关闭，使细胞能够分化成不同类型。任何这些repressor的功能失常或误调控都可能导致发育障碍或癌症等疾病。此外，对repressor的研究在生物技术和医学上具有重要意义。通过了解repressor的工作原理，科学家可以开发针对特定细胞的基因表达调节疗法。例如，如果发现某个特定的repressor在癌细胞中过度活跃，研究人员可能会设计药物来抑制其活性，从而重新激活被沉默的肿瘤抑制基因。这一方法突显了操纵repressor用于治疗目的的潜力。总之，repressor（抑制子）的概念是我们理解原核和真核生物基因调控的基础。repressor控制基因表达的能力对于维持细胞稳态和促进适当发育至关重要。随着研究持续揭示基因调控的复杂性，repressor的角色无疑将继续成为重点，提供生物技术和医学进步的激动人心的机会。