cinchonidine

简明释义

英[sɪŋˈkɒnɪdiːn]美[sɪnˈkonəˌdin]

n. 金鸡纳啶

英英释义

单词用法

同义词

反义词

例句

1.Diastereomers of cinchonine and cinchonidine were fully separated both under isocratic and gradient elutions on the chiral monolithic column.

在等度及梯度洗脱条件下，非对映异构体辛可宁与辛可尼丁被完全分离。

2.A cinchonine imprinted chiral monolithic column was prepared for the separation of the diastereomers of cinchonine and cinchonidine by in situ molecular imprinting technique.

采用原位分子印迹技术，单步制备了一种辛可宁印迹的手性整体柱。

3.A cinchonine imprinted chiral monolithic column was prepared for the separation of the diastereomers of cinchonine and cinchonidine by in situ molecular imprinting technique.

采用原位分子印迹技术，单步制备了一种辛可宁印迹的手性整体柱。

4.Pharmaceutical companies are interested in cinchonidine due to its unique chemical structure.

制药公司对cinchonidine感兴趣，因为它独特的化学结构。

5.The extraction process of cinchonidine from cinchona bark is quite complex.

从奎宁树皮中提取cinchonidine的过程相当复杂。

6.In organic chemistry, cinchonidine serves as a chiral auxiliary.

在有机化学中，cinchonidine作为手性辅助剂使用。

7.Researchers are studying cinchonidine for its potential anti-malarial properties.

研究人员正在研究cinchonidine的潜在抗疟疾特性。

8.The compound cinchonidine is often used in the synthesis of various alkaloids.

化合物cinchonidine常用于合成各种生物碱。

作文

Cinchonidine is a naturally occurring alkaloid derived from the bark of the cinchona tree, which is native to South America. This compound has been studied extensively for its medicinal properties, particularly in the treatment of malaria. The discovery of cinchonidine marked a significant advancement in the field of pharmacology, as it was one of the first effective treatments for this devastating disease. The importance of cinchonidine cannot be overstated; it is not only a crucial component in the history of medicine but also serves as a foundation for the development of other antimalarial drugs.The chemical structure of cinchonidine is quite complex, featuring a quinoline core that is characteristic of many alkaloids. This structure contributes to its biological activity and makes it a valuable subject for scientific research. Researchers have been fascinated by the way cinchonidine interacts with various biological systems, leading to insights into how we can combat malaria more effectively.In addition to its antimalarial properties, cinchonidine has also been investigated for its potential use in treating other conditions. For example, it has shown promise as an analgesic, helping to alleviate pain. This dual functionality highlights the versatility of cinchonidine and underscores the importance of exploring natural compounds for therapeutic applications.The extraction and purification of cinchonidine from the cinchona tree is a meticulous process. Traditionally, the bark of the tree is harvested, dried, and then processed to isolate the active alkaloids. This method, while effective, raises concerns about sustainability and the environmental impact of harvesting wild cinchona trees. As such, there has been a push towards synthesizing cinchonidine in the laboratory to ensure a steady supply for research and medical use.Moreover, the study of cinchonidine has paved the way for the development of synthetic analogs that may offer improved efficacy or reduced side effects compared to the natural compound. Scientists are continuously exploring the modifications of the cinchonidine structure to enhance its pharmacological properties. These efforts are crucial in the fight against drug-resistant strains of malaria, which pose a significant challenge to public health worldwide.Despite the advances made in understanding cinchonidine, there are still many questions to be answered regarding its mechanisms of action and potential side effects. Ongoing research aims to clarify these aspects and to optimize its use in clinical settings. As we continue to learn more about cinchonidine, we gain valuable insights that could lead to new strategies for treating malaria and other diseases.In conclusion, cinchonidine represents a remarkable example of how natural products can lead to significant advancements in medicine. Its historical importance, coupled with its ongoing relevance in research, makes it a compound worthy of study. By understanding and harnessing the power of cinchonidine, we can continue to make strides in the fight against malaria and improve health outcomes for millions of people around the world. As we look to the future, the lessons learned from cinchonidine will undoubtedly inform the next generation of drug discovery and development.

奎宁是一种天然存在的生物碱，来源于原产于南美洲的金鸡纳树的树皮。这种化合物因其药用特性而受到广泛研究，特别是在治疗疟疾方面。奎宁的发现标志着药理学领域的重大进展，因为它是最早有效治疗这种毁灭性疾病的药物之一。奎宁的重要性不容小觑；它不仅是医学历史中的关键组成部分，而且为其他抗疟疾药物的发展奠定了基础。cinchonidine的化学结构相当复杂，具有喹啉核心，这在许多生物碱中是特征性的。这种结构促成了其生物活性，使其成为科学研究中有价值的课题。研究人员对cinchonidine与各种生物系统的相互作用感到着迷，这导致我们对如何更有效地对抗疟疾有了深入的见解。除了抗疟疾特性外，cinchonidine还被研究用于治疗其他疾病。例如，它在镇痛方面显示出希望，有助于缓解疼痛。这种双重功能突显了cinchonidine的多功能性，并强调了探索天然化合物用于治疗应用的重要性。从金鸡纳树中提取和纯化cinchonidine是一个细致的过程。传统上，树皮被收割、干燥，然后加工以分离活性生物碱。这种方法尽管有效，但引发了对可持续性和采伐野生金鸡纳树的环境影响的担忧。因此，人们开始推动在实验室中合成cinchonidine，以确保为研究和医疗用途提供稳定的供应。此外，对cinchonidine的研究为合成类似物的发展铺平了道路，这些类似物可能提供比天然化合物更好的疗效或减少副作用。科学家们不断探索对cinchonidine结构的修改，以增强其药理特性。这些努力对于应对耐药性疟疾株构成的重大公共健康挑战至关重要。尽管对cinchonidine的理解有所进展，但仍有许多关于其作用机制和潜在副作用的问题有待回答。正在进行的研究旨在澄清这些方面，并优化其在临床环境中的使用。随着我们对cinchonidine了解的不断加深，我们获得了宝贵的见解，这可能导致治疗疟疾和其他疾病的新策略。总之，cinchonidine代表了天然产物如何推动医学重大进展的一个杰出例子。它的历史重要性，加上其在研究中的持续相关性，使其成为值得研究的化合物。通过理解和利用cinchonidine的力量，我们可以继续在抗击疟疾的斗争中取得进展，并改善全球数百万人健康结果。展望未来，从cinchonidine中汲取的教训无疑将为下一代药物发现和开发提供指导。