haplotype

简明释义

英[ˈhæpləʊˌtaɪp]美[ˈhæploʊtaɪp]

n. 单体型

英英释义

单词用法

同义词

反义词

例句

1.Methods the theoretical value calculated on the basis of haplotype frequencies and actual finding result from cord blood bank were compared.

方法以脐带血库单体型频率和脐带血库容量为基础计算出某一具体表型的理论值与实际查询结果相比较。

2.The haplotype-based haplotype relative risk( HHRR ) and transmission disequilibrium test ( TDT ) methods were used to analyze the association between DRD4 and ADHD.

传递不平衡检验是基于家系检测疾病位点与标记位点之间连锁与连锁不平衡的经典分析方法。

3.Conclusions: There iso significant association between 3 SNPs of CRP gene and essential hypertension. The ca haplotype may contribute to protection for hypertension.

结论：CRP基因3个SNP单点与原发性高血压病无明显相关性，单倍型CA可能与高血压保护作用有关。

4.Objective To establish a multiplexing Y-STR system and study haplotype frequencies of 4 Y-specific loci in China Han population.

目的建立复合扩增y - STR基因座的体系，获得中国汉族人的单倍型频率。

5.Haplotype analysis placed the critical region to a 7cM interval defined by D1S1653 and D1S2675. These results provide the basis for further identifying the gene responsible for IV disorder.

单体型作图将精确定位区域确定于D1S1653和D1S2675之间7厘摩的范围。这些结果将为进一步克隆寻常型鱼鳞病致病基因提供帮助。

6.Objective To analyse the human leukocyte antigen (HLA) -a, b, DRB1 allele and haplotype frequencies in Jiangxi Chinese Han unrelated bone marrow donors.

目的分析江西汉族骨髓供者人类白细胞抗原(HLA)- A、B、DRB1等位基因频率和HLA单倍型频率。

7.Researchers identified a specific haplotype 单倍型 associated with increased risk of diabetes.

研究人员识别出一种特定的haplotype 单倍型，与糖尿病风险增加相关。

8.Understanding your haplotype 单倍型 can provide insights into your ancestry.

了解你的haplotype 单倍型可以提供有关你祖先的见解。

9.The genetic study focused on the haplotype 单倍型 variations within the population.

这项基因研究集中在该人群中的haplotype 单倍型变异上。

10.In population genetics, a haplotype 单倍型 is often used to trace lineage.

在群体遗传学中，haplotype 单倍型常用于追踪血统。

11.The team discovered a novel haplotype 单倍型 linked to resistance against a particular virus.

研究小组发现了一种与对特定病毒抵抗相关的新型haplotype 单倍型。

作文

Haplotypes play a crucial role in the field of genetics, particularly in understanding human evolution and disease susceptibility. A haplotype is defined as a group of genes within an organism that are inherited together from a single parent. This concept is significant because it allows researchers to trace genetic variations and understand how certain traits or diseases are passed down through generations. For instance, when studying the human genome, scientists often look for specific haplotypes that may be linked to hereditary diseases such as cystic fibrosis or sickle cell anemia.The study of haplotypes is essential in population genetics. By examining the distribution of haplotypes in different populations, researchers can gain insights into the migration patterns of ancient human populations. This information helps in reconstructing the history of human populations and understanding how they adapted to various environments. For example, certain haplotypes may indicate a population's historical exposure to particular pathogens, revealing how they have evolved over time to develop resistance.Moreover, haplotypes are vital in the field of personalized medicine. As we learn more about the human genome, identifying specific haplotypes associated with drug metabolism can lead to more effective treatments tailored to individual patients. This approach not only enhances the efficacy of medications but also minimizes adverse effects, leading to better health outcomes.In addition to their role in medicine and anthropology, haplotypes also contribute to forensic science. In criminal investigations, DNA evidence is often analyzed to identify suspects or victims. By examining specific haplotypes, forensic scientists can determine familial relationships or ancestry, which can be crucial in solving cases. The use of haplotypes in forensics exemplifies how genetic research can have practical applications in society.Despite the advances in our understanding of haplotypes, challenges remain. One major issue is the complexity of the human genome. With millions of possible combinations of alleles, identifying relevant haplotypes can be daunting. Additionally, ethical considerations arise when dealing with genetic information. Privacy concerns and the potential for discrimination based on genetic data are critical issues that must be addressed as we continue to explore the implications of haplotypes in our lives.In conclusion, haplotypes are essential components of genetic research that provide valuable insights into human history, health, and identity. Their study can lead to advancements in medicine, enhance our understanding of evolution, and even aid in criminal investigations. As we delve deeper into the complexities of genetics, the importance of haplotypes will undoubtedly continue to grow, paving the way for innovative solutions to some of the most pressing challenges in healthcare and society. Understanding haplotypes is not just an academic pursuit; it has real-world implications that can improve lives and inform public policy.

单倍型在遗传学领域中发挥着至关重要的作用，特别是在理解人类进化和疾病易感性方面。haplotype被定义为一个生物体内一组基因，这些基因从单个父母那里一起遗传。这个概念非常重要，因为它使研究人员能够追踪基因变异，并了解某些特征或疾病是如何通过代际传递的。例如，在研究人类基因组时，科学家们通常会寻找与遗传疾病（如囊性纤维化或镰状细胞贫血）相关的特定haplotypes。对haplotypes的研究在群体遗传学中至关重要。通过检查不同人群中haplotypes的分布，研究人员可以深入了解古代人类群体的迁徙模式。这些信息有助于重建人类群体的历史，以及理解他们如何适应各种环境。例如，某些haplotypes可能表明一个人群曾经接触过特定病原体，从而揭示他们如何随时间演变以发展抵抗力。此外，haplotypes在个性化医学领域也至关重要。随着我们对人类基因组了解的加深，识别与药物代谢相关的特定haplotypes可以导致更有效的针对个体患者的治疗方法。这种方法不仅提高了药物的疗效，还最小化了不良反应，从而改善健康结果。除了在医学和人类学中的作用外，haplotypes还对法医学有所贡献。在刑事调查中，DNA证据通常被分析以识别嫌疑人或受害者。通过检查特定的haplotypes，法医学科学家可以确定亲属关系或血统，这在破案中至关重要。haplotypes在法医学中的应用例证了遗传研究如何在社会中具有实际应用。尽管我们对haplotypes的理解取得了进展，但仍然存在挑战。一个主要问题是人类基因组的复杂性。由于可能的等位基因组合多达数百万，识别相关的haplotypes可能是艰巨的。此外，涉及遗传信息时会出现伦理问题。隐私问题和基于遗传数据的歧视潜在风险是我们在继续探索haplotypes在生活中的影响时必须解决的关键问题。总之，haplotypes是遗传研究的重要组成部分，为我们提供了关于人类历史、健康和身份的宝贵见解。它们的研究可以推动医学进步，加深我们对进化的理解，甚至帮助刑事调查。随着我们深入探讨遗传学的复杂性，haplotypes的重要性无疑会继续增长，为解决医疗和社会中一些最紧迫的挑战铺平道路。理解haplotypes不仅仅是学术追求；它具有现实世界的影响，可以改善生活并为公共政策提供信息。