nialamide

简明释义

英[ˈnaɪələˌmaɪd]美[ˈnaɪələˌmaɪd]

n. [药] 烟肼酰胺；尼亚酰胺（一种抗抑郁药）

英英释义

单词用法

同义词

反义词

例句

1.Results TAEP can markedly activate MAO B in cerebrum and antagonise the inhibition of MAO B activity by nialamide.

结果TAEP对小鼠脑MAO-B具有明显的激活作用，并具有对抗烟肼酰胺抑制小鼠脑MAO-B活性的作用。

2.Results TAEP can markedly activate MAO B in cerebrum and antagonise the inhibition of MAO B activity by nialamide.

结果TAEP对小鼠脑MAO-B具有明显的激活作用，并具有对抗烟肼酰胺抑制小鼠脑MAO-B活性的作用。

3.In clinical trials, nialamide demonstrated promising results in lowering cholesterol levels.

在临床试验中，尼拉米德在降低胆固醇水平方面显示出良好的效果。

4.Research shows that nialamide can help improve blood circulation.

研究表明尼拉米德可以改善血液循环。

5.The doctor prescribed nialamide for the treatment of hypertension.

医生开了尼拉米德来治疗高血压。

6.Some patients experienced dizziness after taking nialamide.

一些患者在服用尼拉米德后感到头晕。

7.Patients taking nialamide should be monitored for side effects.

服用尼拉米德的患者应监测副作用。

作文

Nialamide is a drug that has been used in the treatment of depression and anxiety disorders. It belongs to a class of medications known as monoamine oxidase inhibitors (MAOIs). These types of drugs work by inhibiting the activity of monoamine oxidase, an enzyme responsible for breaking down neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By preventing this breakdown, nialamide increases the levels of these important chemicals, which can help improve mood and alleviate symptoms of depression.The history of nialamide dates back to the mid-20th century when it was first introduced as an antidepressant. During this time, researchers were exploring various compounds that could potentially enhance mood and treat mental health conditions. Nialamide emerged as a promising candidate due to its ability to influence neurotransmitter levels. However, like many medications, it came with a range of side effects and risks, particularly when combined with certain foods or other medications.One of the key aspects of using nialamide is understanding its dietary restrictions. Patients taking this medication must avoid tyramine-rich foods, such as aged cheeses, cured meats, and fermented products. Tyramine can cause dangerous spikes in blood pressure when consumed with MAOIs, leading to serious health complications. Therefore, education on dietary choices is crucial for those prescribed nialamide.Despite its effectiveness, nialamide is not commonly used today due to the availability of newer antidepressants with fewer side effects and interactions. Selective serotonin reuptake inhibitors (SSRIs) and other modern antidepressants have largely replaced older MAOIs in clinical practice. However, understanding the role of nialamide in the history of psychiatric treatment is important for appreciating the evolution of antidepressant therapies.In recent years, there has been a resurgence of interest in older medications like nialamide as researchers explore their potential benefits in combination with newer treatments. This approach, known as polypharmacy, involves using multiple medications to achieve better therapeutic outcomes for patients with complex mental health issues. While nialamide may not be the first-line treatment, it serves as an important reminder of the diverse tools available for managing depression and anxiety.In conclusion, nialamide represents a significant chapter in the story of antidepressant development. Its unique mechanism of action and historical context provide valuable insights into the challenges and advancements in treating mental health disorders. As we continue to learn more about the brain and its chemistry, medications like nialamide remind us of the ongoing quest for effective mental health treatments. Understanding such drugs helps us appreciate the complexities of psychiatric care and the importance of individualized treatment plans for those struggling with mental health issues.

尼拉胺是一种用于治疗抑郁症和焦虑症的药物。它属于一种称为单胺氧化酶抑制剂（MAOIs）的药物类别。这类药物通过抑制单胺氧化酶的活性来发挥作用，单胺氧化酶是一种负责分解大脑中神经递质如血清素、去甲肾上腺素和多巴胺的酶。通过防止这种分解，尼拉胺增加了这些重要化学物质的水平，从而有助于改善情绪和缓解抑郁症状。尼拉胺的历史可以追溯到20世纪中期，当时它首次被引入作为抗抑郁药。在此期间，研究人员正在探索各种可能增强情绪和治疗心理健康状况的化合物。尼拉胺因其影响神经递质水平的能力而成为一个有前途的候选药物。然而，像许多药物一样，它伴随着一系列副作用和风险，特别是在与某些食物或其他药物结合使用时。使用尼拉胺的一个关键方面是了解其饮食限制。服用该药物的患者必须避免富含酪胺的食物，如陈年奶酪、腌制肉类和发酵产品。酪胺在与MAOIs一起食用时可能会导致血压危险性升高，从而导致严重的健康并发症。因此，对于那些被处方尼拉胺的患者来说，关于饮食选择的教育至关重要。尽管尼拉胺有效，但由于新型抗抑郁药可产生更少的副作用和相互作用，它在今天并不常用。选择性血清素再摄取抑制剂（SSRIs）和其他现代抗抑郁药在临床实践中已大大取代了旧的MAOIs。然而，理解尼拉胺在精神病治疗历史中的角色对于欣赏抗抑郁疗法的发展演变非常重要。近年来，随着研究人员探索它们与新治疗方法结合的潜在益处，对像尼拉胺这样的旧药物的兴趣重新出现。这种方法被称为多药治疗，涉及使用多种药物来实现对复杂心理健康问题患者更好的治疗结果。虽然尼拉胺可能不是首选治疗，但它提醒我们管理抑郁症和焦虑症的多样工具的重要性。总之，尼拉胺代表了抗抑郁药开发故事中的一个重要章节。它独特的作用机制和历史背景为我们提供了关于治疗心理健康障碍中的挑战和进展的宝贵见解。随着我们继续深入了解大脑及其化学成分，像尼拉胺这样的药物提醒我们在有效心理健康治疗中的持续追求。理解这些药物帮助我们欣赏精神护理的复杂性，以及为那些面临心理健康问题的人制定个性化治疗计划的重要性。