micronuclei

简明释义

英[ˌmaɪkroʊˈnjuːklaɪ]美[ˌmaɪkroʊˈnjuːklaɪ]

n. 微核（micronucleus 的复数）

英英释义

单词用法

同义词

反义词

例句

1.Micronuclei (MN) effect induced in the polychromatophilic erythroblast (PCE) of mouse bone marrow by refuse landfill leachate was studied.

研究了垃圾填埋场渗滤液诱发小鼠骨髓嗜多染红细胞（PCE）微核（MN）效应。

2.The possible cause that the micronuclei increased in printing female workers was discussed.

对印刷作业女工微核增高的原因进行了讨论。

3.The micronuclei were not observed in tetrad stage.

四分体阶段无微核出现。

4.The Effect of Quizalofop-p-ethyl on Micronuclei and Nuclear Anomalies in Erythrocytes of Hemiculter leucisculus.

除草剂精禾草克对鲹鲦红细胞微核及核异常的影响。

5.The possible cause that the micronuclei increased in printing female workers was discuss...

对印刷作业女工微核增高的原因进行了讨论。

6.The micronuclei rate induced by potassium dichromate under different experimental conditions with micronucleus test of mouse bone marrow cells was studied.

本文用小鼠骨髓细胞微核试验方法，研究了重铬酸钾在不同实验条件下诱发小鼠微核率的影响。

7.The micronuclei rate of polychromatic erythrocytes of mouse bone marrow (PCEMNR) was used as an index to study the effect of S. punicea Hemsl, a new anti-hepatitis drug, on genetic material of mammal.

本文以小鼠骨髓嗜多染红细胞微核率（PCEMNR）为指标，测定了抗病毒性肝炎新药紫红獐牙莱的提取物对哺乳动物遗传物质的诱变作用。

8.The results are that when the soak of Chinese Medical stone is added during the time of vernalization, contaimination and repairment the micronuclei frequency caused by the alcohol ca…

中华麦饭石可能具有治疗、减轻和预防由饮酒引起的遗传损伤的作用。

9.The assay for micronuclei (微核) is a standard test in mutagenicity studies.

对微核的检测是致突变性研究中的标准测试。

10.Environmental toxicology studies frequently measure micronuclei (微核) to assess the genotoxic effects of pollutants.

环境毒理学研究经常测量微核以评估污染物的基因毒性影响。

11.Researchers found a correlation between high levels of micronuclei (微核) and increased cancer risk in smokers.

研究人员发现高水平的微核与吸烟者的癌症风险增加之间存在相关性。

12.The formation of micronuclei (微核) can indicate exposure to radiation or certain chemicals.

形成微核可能表明接触辐射或某些化学物质。

13.In cancer research, the presence of micronuclei (微核) in cells is often used as an indicator of genomic instability.

在癌症研究中，细胞中存在的微核通常被用作基因组不稳定性的指标。

作文

In the field of genetics and cell biology, the term micronuclei refers to small, extra nuclei that can form in a cell as a result of various cellular processes. These structures are typically associated with chromosomal instability and can be indicative of underlying genetic damage or stress within the cell. Understanding micronuclei is crucial for researchers studying cancer, as they often serve as biomarkers for genomic instability, which is a hallmark of many tumors.When cells divide, they meticulously replicate their DNA and distribute it evenly between the two daughter cells. However, errors can occur during this process, leading to the formation of micronuclei. These errors may arise from factors such as exposure to radiation, chemical agents, or even viral infections. The presence of micronuclei can signal that a cell has experienced some form of genomic insult, prompting researchers to investigate the potential implications for cell health and disease progression.One of the key aspects of studying micronuclei is their role in cancer research. Tumors often exhibit high levels of chromosomal instability, which can lead to the formation of multiple micronuclei. In fact, the detection of these structures in tumor samples can provide valuable insights into the aggressiveness of the cancer and its potential response to treatment. For instance, studies have shown that patients with tumors containing numerous micronuclei may have poorer prognoses compared to those with fewer such structures.Furthermore, the study of micronuclei extends beyond cancer. Researchers are also interested in how these structures relate to other diseases and conditions. For example, certain neurodegenerative diseases have been linked to increased levels of micronuclei, suggesting that they may play a role in the pathogenesis of these disorders. This connection opens new avenues for research, as scientists seek to understand the mechanisms behind micronuclei formation and their implications for cellular health.In the laboratory, scientists utilize various techniques to detect and analyze micronuclei. One common method involves staining cells and examining them under a microscope to identify the presence of these small nuclei. Advanced imaging techniques and molecular assays can also be employed to quantify the frequency of micronuclei in a given cell population, providing valuable data for epidemiological studies.As our understanding of micronuclei continues to grow, it is becoming increasingly clear that these tiny structures hold significant importance in the realm of human health. Their presence serves as a reminder of the delicate balance that exists within our cells and the potential consequences when this balance is disrupted. Ongoing research in this area will undoubtedly shed light on the complexities of cellular behavior and contribute to the development of novel therapeutic strategies aimed at combating cancer and other diseases characterized by genomic instability.In conclusion, micronuclei are more than just cellular anomalies; they are key indicators of genetic health and stability. By studying these structures, scientists can gain insights into the mechanisms of disease, paving the way for advancements in medical research and treatment. As we continue to explore the significance of micronuclei, we move closer to unraveling the mysteries of cellular function and its impact on overall health.

在遗传学和细胞生物学领域，术语micronuclei指的是在细胞中形成的小型额外细胞核，这通常是由于各种细胞过程的结果。这些结构通常与染色体不稳定性相关，并且可以表明细胞内潜在的基因损伤或压力。理解micronuclei对研究癌症的研究人员至关重要，因为它们通常作为基因组不稳定性的生物标志物，而基因组不稳定性是许多肿瘤的特征。当细胞分裂时，它们会仔细复制DNA并将其均匀分配给两个子细胞。然而，在这个过程中可能会发生错误，导致micronuclei的形成。这些错误可能是由于暴露于辐射、化学剂，甚至病毒感染等因素引起的。micronuclei的存在可能表明细胞经历了某种形式的基因组损伤，促使研究人员调查对细胞健康和疾病进展的潜在影响。研究micronuclei的一个关键方面是它们在癌症研究中的作用。肿瘤通常表现出高水平的染色体不稳定性，这可能导致多个micronuclei的形成。事实上，在肿瘤样本中检测到这些结构可以提供有关癌症侵袭性及其对治疗反应的宝贵见解。例如，研究表明，肿瘤中含有大量micronuclei的患者可能比那些含有较少此类结构的患者预后更差。此外，研究micronuclei不仅限于癌症。研究人员还对这些结构与其他疾病和条件之间的关系感兴趣。例如，某些神经退行性疾病与增加的micronuclei水平相关，这表明它们可能在这些疾病的发病机制中发挥作用。这一联系为研究打开了新的途径，因为科学家们寻求理解micronuclei形成背后的机制及其对细胞健康的影响。在实验室中，科学家利用各种技术来检测和分析micronuclei。一种常见的方法涉及对细胞进行染色，并在显微镜下检查以识别这些小核的存在。先进的成像技术和分子检测也可以用来量化给定细胞群体中micronuclei的频率，从而为流行病学研究提供有价值的数据。随着我们对micronuclei理解的不断深入，越来越明显的是这些微小结构在人体健康领域的重要性。它们的存在提醒我们细胞内部存在的微妙平衡以及当这种平衡被打破时可能产生的后果。在这一领域的持续研究无疑将揭示细胞行为的复杂性，并有助于开发新的治疗策略，以应对癌症和其他特征为基因组不稳定的疾病。总之，micronuclei不仅仅是细胞异常；它们是基因健康和稳定性的关键指标。通过研究这些结构，科学家可以获得关于疾病机制的见解，为医学研究和治疗的进步铺平道路。随着我们继续探索micronuclei的重要性，我们将更接近揭示细胞功能的奥秘及其对整体健康的影响。