megakaryocytes

简明释义

英[ˌmɛɡəˈkɛəriəˌsaɪts]美[ˌmɛɡəˈkɛəriəˌsaɪts]

[组织] 巨核细胞

英英释义

单词用法

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例句

1.Out of other 6 IMF patients without JAK2V617F point mutation only 1 patient had thrombosis, and lower counts of platelets in perepheral blood and megakaryocytes in bone marrow.

另6例JAK2V617F点突变阴性患者仅1例有血栓史，血小板数目及骨髓巨核细胞数目相对较低。

2.Objective To investigate the effect of hematopoietic stimulating factors on the expansion of mature megakaryocytes.

目的：探讨造血刺激因子对巨核系成熟细胞体外扩增的影响。

3.Newly diagnosed patients with higher celluler count of megakaryocytes and dysmegakaryopoiesis had less complete remission rate and poor prognosis.

初发时巨核细胞计数增高及出现病态变化者缓解率低，预后不良。

4.This is the appearance of normal bone marrow smear at high magnification. Note the presence of megakaryocytes, erythroid precursors, and granulocytic precursors.

高倍镜下的正常骨髓涂片，可见巨核细胞，红细胞前体细胞和粒细胞前体细胞。

5.Conclusion IPF in peripheral blood can reflect the amount of platelets produced by megakaryocytes, thus contributing to the diagnosis and differential diagnosis of hematological diseases.

结论 外周血网织血小板数量可反映骨髓巨核系统生成血小板的情况，从而用于疾病的诊断和鉴别诊断。

6.The effects of bone marrow stromal cells conditioned medium combined with TPO on the expansion of mature megakaryocytes and CFU-Meg in vitro;

人脐血中是否存在造血基质细胞及其生物学特点如何，脐血基质细胞能否在体外有效扩增，国内外相关的系统性研究较少。

7.Objective To investigate the effect of bone marrow fibroblasts conditioned media on the expansion of megakaryocytes in vitro.

目的：探讨骨髓成纤维细胞条件培养液对体外巨核系细胞生成的促进作用。

8.The differentiation of stem cells into megakaryocytes is a key area of research in hematology.

干细胞向巨核细胞的分化是血液学研究的一个关键领域。

9.Researchers are studying how megakaryocytes can be manipulated for better platelet production.

研究人员正在研究如何操控巨核细胞以提高血小板的产生。

10.In the bone marrow, megakaryocytes play a crucial role in producing platelets.

在骨髓中，巨核细胞 在产生血小板方面发挥着关键作用。

11.During the examination, the doctor noted a high count of megakaryocytes in the patient's bone marrow.

在检查过程中，医生注意到患者骨髓中巨核细胞的数量较高。

12.An increase in megakaryocytes can indicate certain blood disorders.

增加的巨核细胞可能表明某些血液疾病。

作文

The human body is a complex system made up of various types of cells, each serving a specific function. One of the most fascinating types of cells is the megakaryocytes, which play a crucial role in our blood system. These large cells are primarily responsible for the production of platelets, which are essential for blood clotting and wound healing. Understanding the function and importance of megakaryocytes can provide insights into how our body responds to injuries and maintains homeostasis.Megakaryocytes are found in the bone marrow, where they develop from hematopoietic stem cells. These stem cells differentiate into various types of blood cells, including red blood cells, white blood cells, and platelets. The process of megakaryocytes development is quite unique. As they mature, they undergo a process called endomitosis, where the cell's nucleus replicates multiple times without dividing. This results in a single cell with a large, multi-lobed nucleus and an increased cytoplasmic volume. It is this enlarged structure that allows megakaryocytes to produce thousands of platelets.Platelets, or thrombocytes, are small cell fragments that are released into the bloodstream from the megakaryocytes. When a blood vessel is injured, platelets quickly accumulate at the site of damage, adhering to the exposed tissue and each other. This aggregation forms a temporary plug that helps to stop bleeding. Additionally, platelets release various signaling molecules that promote further clotting and healing processes. Without the action of megakaryocytes, our bodies would struggle to stop bleeding from even minor injuries, leading to severe health complications.Research has shown that the number and function of megakaryocytes can be affected by various factors, including age, disease, and environmental influences. For instance, certain medical conditions, such as leukemia or myeloproliferative disorders, can lead to an overproduction of megakaryocytes, resulting in an excess of platelets in the blood. This condition, known as thrombocytosis, can increase the risk of clotting disorders, heart attacks, and strokes. Conversely, a deficiency in megakaryocytes can lead to thrombocytopenia, a condition characterized by low platelet counts, which can result in excessive bleeding and bruising.In conclusion, megakaryocytes are vital components of our hematological system, responsible for producing platelets that are essential for blood clotting and wound healing. A deeper understanding of these cells not only highlights their importance in maintaining vascular integrity but also sheds light on various health issues related to blood disorders. Ongoing research into megakaryocytes and their functions may lead to new therapeutic strategies for treating blood-related diseases, ultimately improving patient outcomes and enhancing our knowledge of human biology.

人体是一个复杂的系统，由各种类型的细胞组成，每种细胞都有其特定的功能。其中一种最引人注目的细胞是巨核细胞，它们在我们的血液系统中起着至关重要的作用。这些大型细胞主要负责产生血小板，而血小板对于血液凝固和伤口愈合至关重要。理解巨核细胞的功能和重要性可以为我们提供有关身体如何应对伤害和维持内稳态的见解。巨核细胞位于骨髓中，它们由造血干细胞发育而来。这些干细胞分化成各种类型的血细胞，包括红细胞、白细胞和血小板。巨核细胞发育的过程非常独特。当它们成熟时，会经历一种称为内有丝分裂的过程，其中细胞的细胞核多次复制而不分裂。这导致一个细胞具有一个大型的、多叶的细胞核和增加的细胞质体积。正是这种扩大的结构使得巨核细胞能够产生数千个血小板。血小板或称为血栓细胞，是从巨核细胞释放到血液中的小细胞碎片。当血管受伤时，血小板迅速聚集在损伤部位，附着在暴露的组织和彼此之间。这种聚集形成了一个临时的塞子，有助于止血。此外，血小板释放各种信号分子，促进进一步的凝血和愈合过程。如果没有巨核细胞的作用，我们的身体在止住即使是轻微伤口的出血方面将会面临困难，从而导致严重的健康并发症。研究表明，巨核细胞的数量和功能会受到多种因素的影响，包括年龄、疾病和环境影响。例如，某些医学状况，如白血病或增生性疾病，会导致巨核细胞的过度生产，导致血液中血小板的过量。这种情况被称为血小板增多症，可能增加血液凝块、心脏病发作和中风的风险。相反，巨核细胞的缺乏可能导致血小板减少症，这是一种以低血小板计数为特征的情况，可能导致过度出血和淤伤。总之，巨核细胞是我们血液系统的重要组成部分，负责产生对血液凝固和伤口愈合至关重要的血小板。深入理解这些细胞不仅突显了它们在维持血管完整性方面的重要性，还揭示了与血液疾病相关的各种健康问题。对巨核细胞及其功能的持续研究可能会导致治疗血液相关疾病的新疗法，从而最终改善患者的预后，并增强我们对人体生物学的认识。