allogeneic

简明释义

英[ˈæləʊˌdʒenɪk]美[ˌælədʒɪˈniɪk]

adj. 同种异体的；同种异系的

英英释义

单词用法

同义词

反义词

例句

1.To further analyze immunoglobulin (Ig) properties of panel reactive antibodies (PRA) and their potential harmful effects on allogeneic renal transplants.

为了进一步解释群体反应性抗体(pra)的免疫球蛋白性质及其对异基因肾移植的潜在威胁。

2.Conclusion: Allogeneic peripheral blood stem cell non-myeloablative transplantation can be selectively used in the treatment of metastasis breast cancer.

结论：异基因非清髓性外周血干细胞移植可选择性地应用于晚期乳腺癌的治疗。

3.However, the researchers evaluated younger patients to see if any might be suitable candidates for allogeneic stem-cell transplantation.

不过研究人员对年轻患者进行评估，看是否任何人都适合干细胞异体移植。

4.Objective To understand the risk of invasive fungal infection at phase of preengraft- ment of allogeneic hematopoietic stem cell transplantation(HSCT).

目的提高对异基因造血干细胞移植后早期深部真菌感染风险的认识。

5.In many centers, cultured epidermal grafts, both autologous and allogeneic, are being used, with promising results.

在很多中心，使用培养的自体或异体表皮移植物取得了大有希望的效果。

6.Objective: To investigate the applicability of treating saddle-nose deformity with allogeneic bone matrix gelatin implant.

目的：研究同种异体骨基质明胶治疗鞍鼻畸形的可行性。

7.Post non myeloablative allogeneic stem cell transplantation (NST) patients usually received DLI one times a month, consecutively 1 ~ 4 times.

非去髓性异基因干细胞移植(nst)患者通常在移植后每月输注1次，连续1 ~4次。

8.Objective: to induce cardiac transplantation tolerance by parabiosis in allogeneic rats and study the mechanism of the allograft tolerance.

目的：通过异基因鼠联体共生诱导心脏移植耐受并探讨其耐受机理。

9.The histological features of skin lesion of graft-versus-host disease (GVHD) following allogeneic bone marrow transplantation were described.

本文介绍异基因骨髓移植后，移植物抗宿主病（GVHD）的皮肤病损组织学特点。

10.In allogeneic stem cell transplantation, cells are taken from a donor who is genetically different.

异基因干细胞移植中，细胞来自于一个基因不同的供体。

11.The patient received an allogeneic transplant from a matched donor.

患者从一位匹配的供体那里接受了异基因移植。

12.Patients may experience graft-versus-host disease after an allogeneic transplant.

患者在接受异基因移植后可能会经历移植物抗宿主病。

13.Researchers are studying the effects of allogeneic immune responses in various diseases.

研究人员正在研究在各种疾病中异基因免疫反应的影响。

14.A successful allogeneic bone marrow transplant can cure certain types of leukemia.

成功的异基因骨髓移植可以治愈某些类型的白血病。

作文

In the field of medicine, particularly in transplantation and immunology, the term allogeneic refers to the transfer of cells, tissues, or organs from one individual to another of the same species who are genetically different. This concept is crucial in understanding how our immune system interacts with foreign cells. For instance, in a typical organ transplant scenario, the donor and recipient may not share identical genetic makeup, which can lead to complications such as rejection of the transplanted organ. The body recognizes the allogeneic cells as foreign invaders, triggering an immune response that can endanger the success of the transplant. Therefore, it is essential for medical professionals to consider the degree of genetic similarity between the donor and recipient when performing such procedures.To illustrate this further, let’s consider bone marrow transplants, which often involve allogeneic donations. Patients suffering from certain blood disorders, such as leukemia, may require a bone marrow transplant to restore healthy blood cell production. In many cases, the best match for a donor is not a relative but an unrelated person from a donor registry. This is where the concept of allogeneic transplants becomes particularly relevant. The closer the genetic match between the donor's and recipient's tissues, the lower the risk of graft-versus-host disease (GVHD), a condition where the donated immune cells attack the recipient’s body. Medical teams use various methods, including HLA typing, to find the most compatible donor.Additionally, allogeneic stem cell therapy has emerged as a promising treatment for various diseases, including certain cancers and genetic disorders. Researchers are continuously studying how to improve the outcomes of allogeneic stem cell transplants by enhancing donor-recipient matching and developing new immunosuppressive therapies to prevent rejection. This ongoing research highlights the importance of understanding the allogeneic nature of these therapies and their implications for patient care.However, the challenges associated with allogeneic transplants extend beyond just immunological responses. Ethical considerations also play a significant role in the decision-making process regarding organ and tissue donation. Ensuring that donors are informed about the risks and benefits of allogeneic transplants, and obtaining proper consent, is paramount. Moreover, the allocation of organs and tissues raises questions about fairness and equity in healthcare systems. As technology advances and our understanding of genetics deepens, the ethical landscape surrounding allogeneic transplants will likely evolve, necessitating ongoing dialogue among medical professionals, ethicists, and society at large.In conclusion, the term allogeneic is fundamental to the fields of transplantation and immunology. It encompasses a range of medical practices that involve the transfer of genetically different cells and tissues between individuals. Understanding the implications of allogeneic transplants, including the potential for rejection and the importance of donor-recipient matching, is vital for improving patient outcomes. As we continue to explore the possibilities of allogeneic therapies, we must also remain vigilant about the ethical considerations that accompany these life-saving procedures. Through continued research and open dialogue, we can enhance our approaches to allogeneic transplants and ultimately provide better care for patients in need.

在医学领域，特别是在移植和免疫学中，“allogeneic”一词指的是将细胞、组织或器官从一个个体转移到另一个基因不同的同种生物个体的过程。这个概念对于理解我们的免疫系统如何与外来细胞相互作用至关重要。例如，在典型的器官移植场景中，供体和接受者可能没有相同的遗传构成，这可能导致排斥等并发症。身体会将这些allogeneic细胞视为外来入侵者，从而触发免疫反应，这可能危及移植的成功。因此，医疗专业人员在进行此类手术时，考虑供体和接受者之间的遗传相似程度是非常重要的。为了更好地说明这一点，我们以骨髓移植为例，通常涉及allogeneic捐献。患有某些血液疾病（如白血病）的患者可能需要骨髓移植，以恢复健康的血细胞生产。在许多情况下，最佳的供体匹配不是亲属，而是来自捐赠者登记处的无关人员。这就是allogeneic移植概念变得特别相关的地方。供体和接受者的组织之间的遗传匹配越接近，发生移植物抗宿主病（GVHD）的风险就越低，这是一种捐赠的免疫细胞攻击接受者身体的状况。医疗团队使用各种方法，包括HLA分型，寻找最兼容的供体。此外，allogeneic干细胞治疗已成为治疗各种疾病（包括某些癌症和遗传疾病）的有前途的方法。研究人员正在不断研究如何通过增强供体与接受者的匹配以及开发新的免疫抑制疗法来改善allogeneic干细胞移植的结果。这项持续的研究强调了理解这些疗法的allogeneic特性及其对患者护理影响的重要性。然而，与allogeneic移植相关的挑战不仅限于免疫反应。伦理考虑在关于器官和组织捐献的决策过程中也发挥着重要作用。确保捐赠者了解allogeneic移植的风险和收益，并获得适当的同意至关重要。此外，器官和组织的分配引发了关于公平和医疗系统中公正的问题。随着技术的进步和我们对遗传学的理解加深，围绕allogeneic移植的伦理格局可能会发展，因此需要医疗专业人员、伦理学家和社会各界之间的持续对话。总之，“allogeneic”一词是移植和免疫学领域的基础。它涵盖了一系列涉及在个体之间转移基因不同的细胞和组织的医学实践。理解allogeneic移植的影响，包括排斥的潜在可能性和供体与接受者匹配的重要性，对于改善患者结果至关重要。随着我们继续探索allogeneic疗法的可能性，我们还必须保持警惕，关注伴随这些拯救生命的程序的伦理考虑。通过持续的研究和开放的对话，我们可以增强对allogeneic移植的处理方式，并最终为需要帮助的患者提供更好的护理。