antiarrhythmic

简明释义

英[ˌæntɪeɪˈrɪðmɪk]美[ænʃɪrˈrɪðmɪk]

adj. [药] 抗心律失常的；抗心律不齐的

英英释义

单词用法

同义词

反义词

例句

1.Methods and Results— We conducted a randomized multicenter comparison of these 2 treatment strategies in patients with paroxysmal AF resistant to at least 1 antiarrhythmic drug.

方法和结果—对于这两种治疗方法，我们在至少对一种抗心律失常药物耐药的陈发性房颤患者中进行了一个随机的多中心的对比研究。

2.Conclusion No one patient developed embolism; although solely using anti-hyperthyroidism medicine can reverse atrial fibrillation, combining with antiarrhythmic drug can shorten the course.

结论用复律药物可缩短房颤的病程，不用药房颤也自行转复，所有病人均未发生明显栓塞症状。

3.The same may also be true for patients with implantable cardioverter defibrillators who have a history of ventricular tachycardia and who are not taking antiarrhythmic medications.

对于有室性心动过速及不服用抗心律失常药物的植入心律转复除颤器患者也需特别注意。

4.Eighty-eight per cent of patients receiving antiarrhythmic drugs in the PVI group, and 71% not receiving these agents, were free of atrial fibrillation at 6 months.

在肺静脉隔离组，88%的患者服用了抗心律失常药物，没有服用抗心律失常药的患者中的71%，在其后6个月没有发生房颤。

5.Its antiarrhythmic effect is evaluated in conscious rabbit and anesthetized rat models of arrhythmia induced by epinephrine and coronary ligation.

采用肾上腺素诱发清醒家兔心律失常和结扎冠状动脉造成麻醉大鼠心律失常模型进行药理试验。

6.The studies of the mechanisms of arrhythmogenesis and the action of antiarrhythmic drugs have already focused on the events of ionic channel currents in isolated single heart cells.

而对心律失常发生机制及药物抗心律失常作用机制的研究，也都聚焦于对心肌细胞离子通道及跨膜离子流的研究。

7.We concluded that diabetes mellitus reduces the antiarrhythmic effects of flecainide , E-4031, and verapamil.

我们推断糖尿病弱氟卡胺、E-4031和维拉帕米的心律失常作用。

8.The antiarrhythmic therapy was effective in reducing the frequency of the episodes.

这种抗心律失常治疗有效减少了发作的频率。

9.The new antiarrhythmic drug showed promising results in clinical trials.

这种新的抗心律失常药物在临床试验中显示出良好的效果。

10.He was advised to avoid caffeine while on antiarrhythmic medication.

他被建议在服用抗心律失常药物期间避免咖啡因。

11.The doctor prescribed an antiarrhythmic medication to manage the patient's irregular heartbeat.

医生开了一种抗心律失常药物来管理患者的不规律心跳。

12.Patients with atrial fibrillation often require antiarrhythmic drugs to maintain a normal heart rhythm.

患有房颤的患者通常需要使用抗心律失常药物来维持正常心律。

作文

The human heart is a complex organ that plays a vital role in maintaining the overall health of the body. One of the most critical functions of the heart is to pump blood efficiently throughout the circulatory system. However, various factors can disrupt this process, leading to irregular heartbeats or arrhythmias. In such cases, medical professionals often turn to medications known as antiarrhythmic drugs. These medications are specifically designed to restore normal heart rhythm and improve the heart's performance. Understanding how antiarrhythmic drugs work can provide valuable insights into their importance in cardiovascular health.Arrhythmias can manifest in several forms, including atrial fibrillation, ventricular tachycardia, and bradycardia. Each type of arrhythmia presents unique challenges and risks, making it essential for healthcare providers to accurately diagnose the condition before initiating treatment. Antiarrhythmic medications function by altering the electrical signals in the heart, thereby stabilizing the heart's rhythm. They can be classified into several categories based on their mechanism of action, including sodium channel blockers, beta-blockers, potassium channel blockers, and calcium channel blockers.Sodium channel blockers, for instance, work by inhibiting the influx of sodium ions during the depolarization phase of the cardiac action potential. This action helps to slow down the heart rate and restore a normal rhythm. On the other hand, beta-blockers reduce the effects of adrenaline on the heart, which can help to decrease heart rate and lower blood pressure, further contributing to the stabilization of heart rhythm. Potassium channel blockers play a crucial role in prolonging the repolarization phase, thus preventing premature contractions that could lead to more severe arrhythmias.While antiarrhythmic medications can be highly effective, they are not without potential side effects. Patients may experience dizziness, fatigue, or even more serious complications, depending on the specific drug and individual health conditions. Therefore, it is crucial for healthcare providers to monitor patients closely and adjust dosages as necessary to minimize risks. In some cases, alternative treatments such as catheter ablation or implantable devices may be recommended if antiarrhythmic drugs fail to provide adequate control of the arrhythmia.In conclusion, antiarrhythmic medications are essential tools in the management of arrhythmias, helping to restore normal heart rhythm and improve patient outcomes. Their ability to target specific pathways in the heart allows for tailored treatment plans that can address the unique needs of each patient. As research continues to advance in the field of cardiology, the development of new and improved antiarrhythmic drugs holds promise for even better management of these potentially life-threatening conditions. Understanding the mechanisms and applications of antiarrhythmic medications is vital for both healthcare professionals and patients alike, as it empowers them to make informed decisions regarding their heart health.

人类的心脏是一个复杂的器官，在维持身体整体健康方面发挥着至关重要的作用。心脏最关键的功能之一是有效地将血液泵送到整个循环系统。然而，各种因素可能会干扰这一过程，导致心跳不规律或心律失常。在这种情况下，医疗专业人员通常会使用称为抗心律失常药物的药物。这些药物专门设计用于恢复正常的心律并改善心脏的功能。理解抗心律失常药物的工作原理可以提供有关其在心血管健康中重要性的宝贵见解。心律失常可以表现为多种形式，包括房颤、室性心动过速和心动过缓。每种类型的心律失常都带来了独特的挑战和风险，因此医疗提供者必须在开始治疗之前准确诊断该病症。抗心律失常药物通过改变心脏中的电信号来发挥作用，从而稳定心脏的节律。根据其作用机制，它们可以分为几类，包括钠通道阻滞剂、β-adrenergic 受体拮抗剂、钾通道阻滞剂和钙通道阻滞剂。例如，钠通道阻滞剂通过抑制钠离子在心脏动作电位去极化阶段的流入来工作。这一作用有助于减慢心率并恢复正常节律。另一方面，β-adrenergic 受体拮抗剂减少肾上腺素对心脏的影响，这可以帮助降低心率并降低血压，进一步有助于心律的稳定。钾通道阻滞剂在延长再极化阶段方面发挥着至关重要的作用，从而防止可能导致更严重心律失常的早期收缩。虽然抗心律失常药物可以非常有效，但它们并非没有潜在的副作用。患者可能会经历头晕、疲劳，甚至更严重的并发症，具体取决于特定药物和个体健康状况。因此，医疗提供者必须密切监测患者，并根据需要调整剂量以最小化风险。在某些情况下，如果抗心律失常药物未能提供足够的心律控制，可能会建议采用其他治疗方法，如导管消融或植入装置。总之，抗心律失常药物是管理心律失常的重要工具，有助于恢复正常的心律并改善患者的预后。它们能够针对心脏中的特定通路，使得可以制定针对每位患者独特需求的个性化治疗方案。随着心脏病学领域研究的不断进展，新型和改进的抗心律失常药物的发展为更好地管理这些潜在威胁生命的疾病带来了希望。理解抗心律失常药物的机制和应用对于医疗专业人员和患者来说都是至关重要的，因为这使他们能够就心脏健康做出明智的决定。