hepatotoxicity

简明释义

英[ˌhepətəʊtɒkˈsɪsəti]美[ˌhepətoʊˌtɒkˈsɪsɪti]

n. 肝毒性；肝中毒；肝脏毒性；肝细胞毒性

英英释义

单词用法

同义词

反义词

例句

1.Benzbromarone can be used in patients with mild to moderate renal insufficiency on a named patient basis but carries a small risk of hepatotoxicity.

苯溴马龙能用于轻中度肾功能不全的患者，但有引起肝毒性的轻度危险性。

2.Objective to analyze the recent five years clinical data of acute drug-induced hepatotoxicity.

目的分析急性药物性肝病发生的类型、药物年龄分布概况。

3.Conclusion: Tiopronin is effective in the prevention and treatment of the hepatotoxicity caused by chemotherapy in patients with malignant tumors, and worthy to be popularized.

结论：凯西菜对恶性肿瘤患者伦疗性肝损害的预防和治疗疗效显著，值得临床推广。

4.This study was designed to evaluate the effects of tea seed oil on CCl4-induced acute hepatotoxicity in rats.

本研究旨在探讨影响茶叶籽油对四氯化碳诱导的急性肝损伤的影响。

5.Objective: to explore hepatotoxicity of troglitazone on rat hepatocytes.

目的：研究曲格列酮的肝细胞毒性及其可能的机制。

6.Other warnings include hepatotoxicity or liver damage, effects on blood pressure and bleeding.

其他还有肝毒性或肝脏损伤以及影响血压和导致出血等警告。

7.Objective To demonstrate the advances on progress of recovery mechanism to cadmium ion-mediated acute hepatotoxicity.

目的了解镉离子介导急性肝损伤与抗损伤机制的研究进展。

8.The advisory committee recommended increased restrictions on the use of acetaminophen to protect people of all ages from potential hepatotoxicity.

顾问委员会推荐加强对对乙酰氨基酚使用的限制，降低不同年龄层儿童发生肝毒性事件的风险。

9.Drug-induced hepatotoxicity was documented in 15% of patients but likely occurred more frequently.

药物诱导的肝毒性被证明存在于15%的患者中，但实际的发生似乎更为频繁。

10.Research indicates that certain herbal supplements can cause hepatotoxicity in susceptible individuals.

研究表明，某些草本补充剂可能在易感个体中引发肝毒性。

11.The clinical trial was halted due to unexpected cases of hepatotoxicity among participants.

由于参与者中出现意外的肝毒性病例，临床试验被暂停。

12.Monitoring liver function is crucial for detecting early signs of hepatotoxicity in patients on chemotherapy.

监测肝功能对于检测接受化疗患者早期的肝毒性迹象至关重要。

13.Patients taking high doses of acetaminophen are at risk of hepatotoxicity if not monitored properly.

如果没有得到适当监测，服用高剂量对乙酰氨基酚的患者面临肝毒性的风险。

14.The new drug showed significant hepatotoxicity, leading to concerns about its safety profile.

这种新药显示出显著的肝毒性，引发了对其安全性的担忧。

作文

Hepatotoxicity is a term that refers to the damage caused to the liver by various substances, including drugs, alcohol, and certain chemicals. The liver is a vital organ in the body, responsible for detoxifying harmful substances, producing bile for digestion, and regulating metabolism. When the liver is exposed to toxic substances, it can lead to serious health complications. Understanding hepatotoxicity is essential for both healthcare professionals and patients, as it helps in preventing and managing liver damage effectively.One of the most common causes of hepatotoxicity is the use of prescription medications. Many drugs, although beneficial for treating various conditions, can have adverse effects on the liver. For example, acetaminophen, a widely used pain reliever, can be highly toxic to the liver when taken in excessive amounts. This highlights the importance of adhering to prescribed dosages and being aware of potential interactions with other medications or substances.Alcohol consumption is another significant contributor to hepatotoxicity. Chronic alcohol abuse can lead to alcoholic liver disease, which encompasses a range of conditions such as fatty liver, hepatitis, and cirrhosis. These conditions can severely impair liver function and may even be life-threatening. Education about responsible drinking and the risks associated with excessive alcohol intake is crucial in preventing hepatotoxicity related to alcohol.In addition to medications and alcohol, certain industrial chemicals and environmental toxins can also cause hepatotoxicity. For instance, exposure to solvents, pesticides, and heavy metals can result in liver damage over time. Workers in industries where they are exposed to such substances should be educated about safety protocols and the importance of using protective equipment to minimize the risk of liver injury.Moreover, herbal supplements and natural remedies are often perceived as safe alternatives to conventional medicine. However, some herbal products can also be hepatotoxic. For example, certain traditional Chinese herbs and weight-loss supplements have been linked to liver damage. It is essential for individuals to consult healthcare professionals before starting any new supplement regimen to avoid potential hepatotoxicity.The symptoms of hepatotoxicity can vary widely, ranging from mild to severe. Some individuals may experience nausea, vomiting, fatigue, and abdominal pain, while others may develop jaundice, characterized by yellowing of the skin and eyes. In severe cases, liver failure can occur, necessitating urgent medical intervention. Regular liver function tests can help in the early detection of liver damage, allowing for timely treatment and prevention of further complications.In conclusion, hepatotoxicity is a significant public health concern that can arise from various sources, including medications, alcohol, chemicals, and herbal supplements. Awareness and education about the risks associated with these substances are vital in preventing liver damage. Healthcare providers play a crucial role in monitoring liver health and guiding patients in making informed decisions about their health. By understanding hepatotoxicity, we can take proactive steps to protect our liver and overall health.

肝毒性是一个术语，指的是各种物质（包括药物、酒精和某些化学品）对肝脏造成的损害。肝脏是身体中的一个重要器官，负责解毒有害物质、产生消化所需的胆汁以及调节新陈代谢。当肝脏暴露于有毒物质时，可能导致严重的健康并发症。理解肝毒性对于医疗专业人员和患者都至关重要，因为这有助于有效预防和管理肝脏损伤。引起肝毒性的最常见原因之一是处方药的使用。许多药物虽然对治疗各种疾病有益，但可能对肝脏产生不良影响。例如，乙酰氨基酚是一种广泛使用的止痛药，当过量服用时，对肝脏具有高度毒性。这突显了遵循处方剂量的重要性，并意识到与其他药物或物质的潜在相互作用。酒精消费是另一个导致肝毒性的重要因素。长期酗酒会导致酒精性肝病，包括脂肪肝、肝炎和肝硬化等一系列病症。这些病症可能严重损害肝功能，甚至危及生命。关于负责任饮酒和过量饮酒所带来的风险的教育，对于预防与酒精相关的肝毒性至关重要。除了药物和酒精，某些工业化学品和环境毒素也会导致肝毒性。例如，接触溶剂、农药和重金属可能会随着时间的推移导致肝脏损害。在接触这些物质的行业工作的工人应接受有关安全协议的教育，并了解使用防护设备以降低肝损伤风险的重要性。此外，草本补充剂和天然疗法通常被认为是传统医学的安全替代品。然而，一些草本产品也可能具有肝毒性。例如，某些传统中药和减肥补充剂与肝脏损伤有关。个人在开始任何新的补充剂方案之前，咨询医疗专业人员以避免潜在的肝毒性是至关重要的。肝毒性的症状可能因人而异，从轻微到严重。一些人可能会出现恶心、呕吐、疲劳和腹痛，而其他人可能会出现黄疸，表现为皮肤和眼睛发黄。在严重情况下，可能会发生肝衰竭，需要紧急医疗干预。定期进行肝功能测试可以帮助早期发现肝损伤，从而及时治疗并防止进一步的并发症。总之，肝毒性是一个重要的公共健康问题，可能由多种来源引起，包括药物、酒精、化学品和草本补充剂。提高人们对这些物质相关风险的意识和教育对于预防肝脏损伤至关重要。医疗提供者在监测肝脏健康和指导患者做出明智的健康决策方面发挥着关键作用。通过理解肝毒性，我们可以采取积极措施保护我们的肝脏和整体健康。