hexamethonium

简明释义

英[/ˌhɛk.səˈmɛθ.ə.ni.əm/]美[/ˌhɛk.səˈmɛθ.ə.ni.əm/]

n. 六甲铵（降血压药）

英英释义

单词用法

同义词

反义词

例句

1.The hypotensive action still persisted after administration of the ganglion blocking agent, hexamethonium.

在给予神经节阻断药(六烷双铵)后，链霉素的降压效应仍然表现。

2.The excitatory effect of lidocaine can not be changed by pretreatment of hexamethonium bromide and atropine.

此效应不受溴化六甲双铵和阿托品的影响。

3.To find out, scientists led by Dr. Alkis Togias of Johns Hopkins University had Roche and other healthy volunteers inhale a drug called hexamethonium.

为了寻找答案，约翰-霍普金斯大学的AlkisTogias博士让Roche和其他一些健康志愿者吸入一种叫做六甲铵的药物。

4.The review board, OHRP charges, never asked for data on the safety of inhaled hexamethonium in people.

人类研究保护办公室还指控复核委员会从未索要有关人体可吸入的六甲铵的安全用量方面的数据。

5.Atropine, verapamil and hexamethonium partly blocked the increased action of rhubarb on the isolated strips of gastric antrum in guinea pigs.

阿托品、维拉·帕米和六烃季胺部分阻断大黄对豚鼠胃窦环行肌条的兴奋作用。

6.To find out, scientists led by Dr. Alkis Togias of Johns Hopkins University had Roche and other healthy volunteers inhale a drug called hexamethonium.

为了寻找答案，约翰-霍普金斯大学的AlkisTogias博士让Roche和其他一些健康志愿者吸入一种叫做六甲铵的药物。

7.The use of hexamethonium 六甲基铵 has declined due to the availability of newer antihypertensive drugs.

由于新型降压药的出现，六甲基铵的使用已减少。

8.Doctors sometimes prescribe hexamethonium 六甲基铵 for patients with severe autonomic dysfunction.

医生有时会为严重自主神经功能障碍的患者开处方六甲基铵。

9.The mechanism of action of hexamethonium 六甲基铵 involves blocking nicotinic receptors.

六甲基铵的作用机制涉及阻断尼古丁受体。

10.Adverse effects of hexamethonium 六甲基铵 may include dry mouth and constipation.

使用六甲基铵可能出现的不良反应包括口干和便秘。

11.In clinical trials, researchers tested the effects of hexamethonium 六甲基铵 on hypertension.

在临床试验中，研究人员测试了六甲基铵对高血压的影响。

作文

In the field of pharmacology, understanding various compounds and their effects on the human body is crucial. One such compound that has garnered attention is hexamethonium. This drug was primarily used as an antihypertensive agent, particularly in the mid-20th century. It works by blocking the transmission of nerve impulses in the autonomic nervous system, specifically at the ganglionic synapses. This mechanism of action makes hexamethonium a unique substance in the treatment of high blood pressure.The discovery of hexamethonium marked a significant advancement in medical science. Before its introduction, treatment options for hypertension were limited and often came with severe side effects. Hexamethonium offered a new avenue for patients who struggled to manage their blood pressure through traditional means. By inhibiting the sympathetic nervous system, it effectively reduced heart rate and dilated blood vessels, leading to lower blood pressure levels.However, the use of hexamethonium was not without complications. Patients often experienced side effects such as dry mouth, constipation, and blurred vision due to the drug's impact on the autonomic nervous system. These adverse effects raised concerns among healthcare providers and patients alike. As research progressed, alternative medications with fewer side effects emerged, leading to a decline in the use of hexamethonium in clinical practice.Despite its waning popularity, hexamethonium remains an important part of pharmacological history. It serves as a reminder of the ongoing evolution in the treatment of hypertension and the constant search for better therapeutic options. The study of hexamethonium also highlights the complexities of drug interactions within the body, emphasizing the need for careful consideration when prescribing medications.Moreover, hexamethonium has been utilized in research settings to better understand the autonomic nervous system. Its ability to block ganglionic transmission has provided insights into how the nervous system regulates cardiovascular functions. Researchers have explored its effects not only on blood pressure but also on various physiological processes, contributing to a deeper understanding of human health.In conclusion, hexamethonium is more than just a pharmaceutical compound; it represents a pivotal moment in the development of antihypertensive therapies. While its clinical use has diminished, the legacy of hexamethonium continues to influence medical research and practice. Understanding its mechanisms and effects can provide valuable lessons for future drug development and patient care. As we move forward in the field of medicine, the lessons learned from hexamethonium will undoubtedly shape the landscape of pharmacotherapy for years to come.

在药理学领域，理解各种化合物及其对人体的影响至关重要。其中一种引起关注的化合物是六甲基铵。这种药物主要用作抗高血压剂，尤其是在20世纪中叶。它通过阻断自主神经系统中神经冲动的传递，特别是在神经节突触处，发挥作用。这种作用机制使得六甲基铵在高血压治疗中成为一种独特的物质。六甲基铵的发现标志着医学科学的一次重大进步。在其引入之前，高血压的治疗选择有限，且通常伴随着严重的副作用。六甲基铵为那些难以通过传统手段控制血压的患者提供了一条新的途径。通过抑制交感神经系统，它有效降低了心率并扩张了血管，从而导致血压水平降低。然而，使用六甲基铵并非没有并发症。由于该药物对自主神经系统的影响，患者常常会经历干口、便秘和视力模糊等副作用。这些不良反应引起了医疗提供者和患者的担忧。随着研究的进展，具有更少副作用的替代药物相继出现，导致六甲基铵在临床实践中的使用逐渐减少。尽管其流行度下降，六甲基铵仍然是药理学历史中的一个重要组成部分。它提醒我们高血压治疗的持续演变以及对更好治疗选择的不断追求。对六甲基铵的研究也突显了药物在体内相互作用的复杂性，强调在开处方时需要谨慎考虑。此外，六甲基铵还被用于研究环境，以更好地理解自主神经系统。它阻断神经节传输的能力提供了对神经系统如何调节心血管功能的见解。研究人员探讨了它对血压的影响以及对各种生理过程的影响，为人类健康的深入理解做出了贡献。总之，六甲基铵不仅仅是一种药物化合物；它代表了抗高血压疗法发展的一个关键时刻。尽管其临床使用减少，但六甲基铵的遗产依然继续影响医学研究和实践。理解其机制和影响可以为未来的药物开发和患者护理提供宝贵的经验教训。随着我们在医学领域的前进，从六甲基铵中吸取的教训无疑将塑造未来几年药物治疗的格局。