flagellin

简明释义

英[fləˈdʒelɪn]美[fləˈdʒelɪn]

n. [生化] 鞭毛蛋白

英英释义

单词用法

同义词

反义词

例句

1.Results: (1) Molecular quantity of the purified flagellin was about 65kd by SDS-PAGE electrophoresis.

实验结果：(1)纯化的鞭毛蛋白经sDS - PAGE电泳，分子量约为65kd。

2.ResultsThe PCR by specific flagellin gene primer has high sensitivity. All of 3 controls were negative.

结果用鞭毛蛋白基因作引物的PCR方法具有高灵敏度，其他3种对照结果阴性。

3.CBLB502 is a polypeptide drug derived from a portion of Salmonella flagellin that binds to and potently activates TLR5.

CBLB502是一种多肽药物，它来源于沙门氏菌鞭毛蛋白的一部分，结合并有效地激活tlr5。

4.CBLB502 is a polypeptide drug derived from a portion of Salmonella flagellin that binds to and potently activates TLR5.

CBLB502是一种多肽药物，它来源于沙门氏菌鞭毛蛋白的一部分，结合并有效地激活tlr5。

5.The immune system recognizes flagellin as a pathogen-associated molecular pattern.

免疫系统将鞭毛蛋白识别为病原体相关分子模式。

6.The presence of flagellin in the environment can trigger an inflammatory response.

环境中存在的鞭毛蛋白可以引发炎症反应。

7.In vaccines, flagellin can be used to enhance the immune response.

在疫苗中，鞭毛蛋白可以用来增强免疫反应。

8.Some studies suggest that flagellin may play a role in gut health.

一些研究表明，鞭毛蛋白可能在肠道健康中发挥作用。

9.Researchers are studying the role of flagellin in bacterial motility.

研究人员正在研究鞭毛蛋白在细菌运动中的作用。

作文

In the fascinating world of microbiology, the study of bacterial structures and their components reveals much about their survival mechanisms and interactions with host organisms. One such component is a protein known as flagellin, which plays a crucial role in the formation of flagella—long, whip-like appendages that enable bacteria to move. The significance of flagellin extends beyond mere locomotion; it also serves as a vital component in the immune response of many organisms. Flagella are essential for motility in various bacteria, allowing them to swim through liquid environments. The structure of flagella is primarily composed of flagellin, which assembles into a helical filament. This filament rotates like a propeller, providing the thrust necessary for the bacterium to navigate its surroundings. The ability to move towards nutrients or away from harmful substances is a fundamental survival strategy for these microorganisms. Interestingly, flagellin is not just a structural protein; it also acts as a potent immunogenic molecule. When bacteria with flagella invade a host, the immune system can recognize flagellin as a foreign substance. This recognition triggers an immune response, leading to the production of antibodies and the activation of various immune cells. In this way, flagellin serves as a double-edged sword, aiding in both bacterial motility and the elicitation of an immune response. Research has shown that different bacteria produce variations of flagellin, which can influence how effectively they evade the host's immune system. Some pathogens have evolved mechanisms to modify their flagellin proteins, allowing them to escape detection by the immune system. This adaptability highlights the ongoing evolutionary arms race between bacteria and their hosts. Moreover, the study of flagellin has implications for vaccine development. By understanding how flagellin interacts with the immune system, scientists can design vaccines that utilize this protein to enhance immune responses against specific bacterial infections. For instance, some vaccines incorporate flagellin as an adjuvant, a substance that boosts the body's immune response to the vaccine's active ingredient. In conclusion, flagellin is a remarkable protein that exemplifies the complexity of microbial life. Its role in bacterial motility and immune system interaction underscores the intricate relationships between microorganisms and their hosts. As research continues to uncover the multifaceted functions of flagellin, we gain deeper insights into microbial behavior and potential therapeutic applications. Understanding flagellin not only enriches our knowledge of microbiology but also opens new avenues for combating infectious diseases. In summary, the exploration of flagellin offers a window into the dynamic world of bacteria, showcasing the delicate balance between pathogenicity and host defense mechanisms. As we delve further into the molecular intricacies of life, proteins like flagellin remind us of the sophistication and resilience of microorganisms in their quest for survival.

在微生物学的迷人世界中，细菌结构及其成分的研究揭示了它们的生存机制以及与宿主生物的相互作用。其中一个重要成分是被称为flagellin的蛋白质，它在鞭毛的形成中发挥着关键作用——鞭毛是长而像鞭子一样的附属物，使细菌能够移动。flagellin的重要性超越了单纯的运动；它还作为许多生物免疫反应中的一个重要组成部分。鞭毛对许多细菌的运动能力至关重要，使它们能够在液体环境中游动。鞭毛的结构主要由flagellin组成，后者组装成螺旋状的细丝。这种细丝像螺旋桨一样旋转，提供细菌在周围环境中导航所需的推力。朝向营养物质或远离有害物质的能力是这些微生物基本的生存策略。有趣的是，flagellin不仅仅是一种结构蛋白；它还是一种强效的免疫原性分子。当带有鞭毛的细菌侵入宿主时，免疫系统可以将flagellin识别为外来物质。这种识别会触发免疫反应，导致抗体的产生和各种免疫细胞的激活。通过这种方式，flagellin充当了一把双刃剑，既有助于细菌运动，又引发免疫反应。研究表明，不同的细菌产生变异的flagellin，这可能影响它们逃避宿主免疫系统的能力。一些病原体已经进化出修改其flagellin蛋白质的机制，使其能够逃避免疫系统的检测。这种适应性突显了细菌与宿主之间持续的进化军备竞赛。此外，flagellin的研究对疫苗开发具有重要意义。通过了解flagellin如何与免疫系统相互作用，科学家可以设计利用这种蛋白质增强特定细菌感染免疫反应的疫苗。例如，一些疫苗将flagellin作为佐剂，佐剂是一种增强身体对疫苗有效成分免疫反应的物质。总之，flagellin是一种出色的蛋白质，它体现了微生物生活的复杂性。它在细菌运动和免疫系统相互作用中的作用强调了微生物与宿主之间复杂的关系。随着研究不断揭示flagellin的多方面功能，我们对微生物行为和潜在治疗应用的理解也在加深。了解flagellin不仅丰富了我们对微生物学的知识，也为对抗传染病开辟了新途径。总之，探索flagellin为我们提供了一个观察细菌动态世界的窗口，展示了致病性与宿主防御机制之间的微妙平衡。随着我们进一步深入生命的分子复杂性，像flagellin这样的蛋白质提醒我们微生物在生存追求中的复杂性和韧性。