hemizygous

简明释义

英[ˌhemɪˈzaɪɡəs]美[ˌhemɪˈzaɪɡəs]

adj. [遗] 半合子的

英英释义

单词用法

同义词

反义词

例句

1.Figure 9. case 7. additional vessel ( purple ) behind the 4 - chamber view next to the aorta ( red ). this vessel represents an azygous or hemizygous continuation of an interrupted inferior vena cava.

图9病例7四腔心切面显示靠近主动脉（红色）处的额外的一条静脉（紫色） 。这条血管表示的是下腔静脉中断后在单侧的延续。

2.Figure 9. case 7. additional vessel ( purple ) behind the 4 - chamber view next to the aorta ( red ). this vessel represents an azygous or hemizygous continuation of an interrupted inferior vena cava.

图9病例7四腔心切面显示靠近主动脉（红色）处的额外的一条静脉（紫色） 。这条血管表示的是下腔静脉中断后在单侧的延续。

3.Figure 9. Case 7. Additional vessel (purple) behind the 4-chamber view next to the aorta (red). This vessel represents an azygous or hemizygous continuation of an interrupted inferior vena cava.

图9病例7四腔心切面显示靠近主动脉(红色)处的额外的一条静脉(紫色)。这条血管表示的是下腔静脉中断后在单侧的延续。

4.In humans, males are considered hemizygous 半合子 for genes on the X chromosome.

在人体中，男性被认为是X染色体上基因的hemizygous 半合子。

5.The hemizygous 半合子 condition often arises in cases of sex-linked inheritance.

在性联遗传的情况下，hemizygous 半合子 状态经常出现。

6.When studying genetics, it is important to identify whether an organism is hemizygous 半合子 for a particular allele.

在研究遗传学时，确定一个生物体是否对于特定等位基因是hemizygous 半合子 是很重要的。

7.Research has shown that hemizygous 半合子 mutations can lead to specific phenotypic traits.

研究表明，hemizygous 半合子 突变可以导致特定的表型特征。

8.The hemizygous 半合子 state of a gene can influence an individual's susceptibility to certain diseases.

基因的hemizygous 半合子 状态可以影响个体对某些疾病的易感性。

作文

In the field of genetics, understanding the various genetic configurations is crucial for both scientific research and clinical applications. One such configuration is referred to as hemizygous, which describes a specific condition where an individual has only one copy of a gene instead of the usual two. This term is particularly relevant in the context of sex chromosomes, where males typically have one X and one Y chromosome, making them hemizygous for genes located on the X chromosome. The concept of hemizygous is significant when discussing X-linked traits and disorders. For instance, if a gene associated with color blindness is located on the X chromosome, males, who are hemizygous for this gene, will express the trait if they inherit the allele associated with color blindness. In contrast, females, who have two X chromosomes, can be homozygous or heterozygous for the same gene, which means they have two copies that may or may not express the trait depending on whether the alleles are the same or different. This difference in genetic configuration leads to varied expressions of certain traits and diseases between males and females. For example, conditions such as hemophilia and Duchenne muscular dystrophy are more prevalent in males due to their hemizygous state concerning the X chromosome. Understanding the implications of being hemizygous is essential for genetic counseling, as it helps predict the likelihood of passing on genetic conditions to offspring. Moreover, the study of hemizygous individuals extends beyond human genetics. In research involving model organisms, such as mice, scientists often create hemizygous strains to investigate the effects of specific genes. By manipulating the genetic makeup of these organisms, researchers can observe phenotypic changes and better understand gene function and interaction. Additionally, the hemizygous state is not limited to sex-linked genes. It can also occur in other genetic contexts, such as when a deletion occurs on one chromosome, leaving only one functional copy of a gene. This situation may lead to dosage sensitivity, where the amount of gene product is critical for normal function. Understanding hemizygous conditions aids in recognizing how gene dosage affects health and disease. In conclusion, the term hemizygous encapsulates a vital aspect of genetic inheritance and expression. Its significance is evident in various biological contexts, from human health to experimental genetics. By grasping the concept of hemizygous individuals, we can enhance our understanding of genetic diversity and its implications in both health and disease management. As research continues to evolve, the exploration of hemizygous states will undoubtedly yield further insights into the complexities of genetic inheritance and expression, paving the way for advancements in medical science and personalized medicine.

在遗传学领域，理解各种遗传配置对于科学研究和临床应用至关重要。其中一个配置被称为半合子，它描述了一种特定的状态，即个体仅拥有一个基因拷贝而不是通常的两个。这个术语在性染色体的背景下尤其相关，因为男性通常有一个X和一个Y染色体，使他们对于位于X染色体上的基因处于半合子状态。半合子的概念在讨论X连锁性状和疾病时显得尤为重要。例如，如果与色盲相关的基因位于X染色体上，男性作为半合子，如果继承了与色盲相关的等位基因，就会表现出这一特征。相比之下，女性有两个X染色体，可以是纯合或杂合，这意味着她们有两个拷贝，这两个拷贝可能相同也可能不同，具体表现取决于等位基因的相同性。这种遗传配置的差异导致了男性和女性在某些性状和疾病表现上的不同。例如，血友病和杜氏肌营养不良等疾病在男性中更为普遍，因为他们在X染色体上处于半合子状态。理解半合子的含义对于遗传咨询至关重要，因为它有助于预测将遗传病传递给后代的可能性。此外，半合子个体的研究不仅限于人类遗传学。在涉及模式生物（如小鼠）的研究中，科学家们常常创建半合子品系，以研究特定基因的影响。通过操控这些生物的遗传构成，研究人员可以观察表型变化，更好地理解基因功能和相互作用。此外，半合子状态并不限于性连锁基因。它还可以在其他遗传背景中发生，例如当一个染色体上发生缺失，仅留下一个功能拷贝的基因。这种情况可能导致剂量敏感性，其中基因产物的数量对正常功能至关重要。理解半合子状态有助于认识基因剂量如何影响健康和疾病。总之，半合子这一术语概括了遗传遗传和表现的重要方面。它的重要性在各种生物学背景中显而易见，从人类健康到实验遗传学。通过掌握半合子个体的概念，我们可以增强对遗传多样性及其在健康和疾病管理中影响的理解。随着研究的不断发展，对半合子状态的探索无疑将进一步揭示遗传遗传和表现的复杂性，为医学科学和个性化医疗的进步铺平道路。