pyrogenicity

简明释义

英[ˌpaɪrəʊdʒəˈnɪsɪti]美[ˌpaɪrəˌdʒɛnˈɪsɪti]

产热原性

英英释义

单词用法

同义词

反义词

例句

1.At the second of these AD hoc conferences, as at the first, there were two chief problems the pyrogenicity of the preparations then available, and their instability.

在专案会议的第二次会议，首先，这里有两个主要问题，一个是致热原性的准备工作及可用性，它们的不稳定性。

2.At the second of these AD hoc conferences, as at the first, there were two chief problems the pyrogenicity of the preparations then available, and their instability.

在专案会议的第二次会议，首先，这里有两个主要问题，一个是致热原性的准备工作及可用性，它们的不稳定性。

3.Besides, mouse toxicity test, rabbit pyrogenicity test and mouse efficiency test also meet the requirements.

此外，小鼠毒性、家兔热原及效力试验显示制得菌苗均符合规程要求。

4.Researchers are investigating new methods to reduce the pyrogenicity of biologics.

研究人员正在调查减少生物制剂的致热性的新方法。

5.The presence of endotoxins can significantly increase the pyrogenicity of a pharmaceutical product.

内毒素的存在可以显著增加药品的致热性。

6.Manufacturers must test for pyrogenicity in medical devices to ensure patient safety.

制造商必须测试医疗设备的致热性以确保患者安全。

7.The study aimed to evaluate the pyrogenicity of the new vaccine before it was approved for human trials.

这项研究旨在评估新疫苗在批准进行人体试验之前的致热性。

8.Regulatory agencies require thorough documentation of pyrogenicity tests for all injectable drugs.

监管机构要求对所有注射药物进行详尽的致热性测试文档。

作文

Pyrogenicity is a term that refers to the ability of a substance to induce fever in an organism. This phenomenon is particularly important in the fields of medicine and pharmacology, as it can significantly impact patient care and the development of pharmaceutical products. Understanding the concept of pyrogenicity (致热性) is crucial for ensuring the safety and efficacy of medical treatments. Fever is a natural response of the body to infection or inflammation, triggered by pyrogens, which are substances that cause an increase in body temperature. Pyrogens can be classified into two main categories: endogenous and exogenous. Endogenous pyrogens are produced by the body’s immune system in response to pathogens, while exogenous pyrogens originate from outside the body, such as bacterial toxins or certain medications. In clinical settings, the presence of pyrogenicity (致热性) in pharmaceuticals can lead to serious complications. For instance, if a medication intended for intravenous use contains pyrogenic substances, it can cause febrile reactions in patients, resulting in discomfort and potentially severe health issues. Therefore, rigorous testing for pyrogenicity (致热性) is a standard procedure in the pharmaceutical industry. This includes methods such as the Limulus Amebocyte Lysate (LAL) test, which is widely used to detect endotoxins in injectable drugs and medical devices.The implications of pyrogenicity (致热性) extend beyond pharmaceuticals; they also play a significant role in vaccine development. Vaccines must be free from pyrogens to ensure that they do not induce fever when administered. This requirement is critical for maintaining public trust in vaccination programs, as adverse reactions can deter individuals from receiving necessary immunizations. Scientists and researchers work diligently to minimize pyrogenicity (致热性) in vaccine formulations, employing various purification techniques to eliminate potential contaminants.Moreover, understanding pyrogenicity (致热性) is essential for the safety of medical devices. Devices that come into contact with the bloodstream, such as catheters and implants, must be meticulously tested for pyrogenic properties. Any device that fails to meet the stringent standards for pyrogenicity (致热性) poses a risk to patients, potentially leading to severe complications such as septic shock.In conclusion, the concept of pyrogenicity (致热性) is a fundamental aspect of modern medicine and pharmacology. It highlights the importance of ensuring that medical products are safe for patient use. Through rigorous testing and adherence to safety standards, healthcare professionals aim to mitigate the risks associated with pyrogenic substances. As our understanding of pyrogenicity (致热性) continues to evolve, it will undoubtedly play a critical role in the advancement of medical science and the development of safer therapeutic options for patients worldwide.

致热性是一个术语，指的是一种物质引起生物体发热的能力。这种现象在医学和药理学领域尤为重要，因为它会显著影响患者护理和药品开发。理解pyrogenicity（致热性）的概念对于确保医疗治疗的安全性和有效性至关重要。发热是身体对感染或炎症的自然反应，由致热源触发，致热源是导致体温升高的物质。致热源可以分为两大类：内源性和外源性。内源性致热源是由身体免疫系统在对病原体反应时产生的，而外源性致热源则来源于体外，例如细菌毒素或某些药物。在临床环境中，药品中的pyrogenicity（致热性）可能导致严重并发症。例如，如果一种用于静脉注射的药物含有致热物质，可能会在患者中引发发热反应，导致不适甚至严重健康问题。因此，对pyrogenicity（致热性）的严格检测是制药行业的标准程序。这包括如蜚蠊血浆试验（LAL）等方法，该方法广泛用于检测注射药物和医疗设备中的内毒素。pyrogenicity（致热性）的影响不仅限于药品；它们在疫苗开发中也发挥着重要作用。疫苗必须无致热源，以确保在接种时不会引发发热。这一要求对于维持公众对疫苗接种计划的信任至关重要，因为不良反应可能会阻止人们接受必要的免疫接种。科学家和研究人员努力减少疫苗配方中的pyrogenicity（致热性），采用各种纯化技术以消除潜在的污染物。此外，理解pyrogenicity（致热性）对医疗设备的安全性至关重要。与血液接触的设备，如导管和植入物，必须经过严格的致热性测试。任何未能满足pyrogenicity（致热性）严格标准的设备都对患者构成风险，可能导致严重并发症，如脓毒性休克。总之，pyrogenicity（致热性）的概念是现代医学和药理学的基本方面。它突显了确保医疗产品对患者使用安全的重要性。通过严格的测试和遵循安全标准，医疗专业人员旨在减轻与致热物质相关的风险。随着我们对pyrogenicity（致热性）理解的不断发展，它无疑将在医学科学的进步和为全球患者开发更安全的治疗选择中发挥关键作用。