angiogenesis

简明释义

英[ˌændʒɪəˈɡenɪsɪs]美[ˌændʒɪoʊˈdʒenɪsɪs]

n. 血管生成；血管再生术

英英释义

单词用法

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例句

1.Tumor associated angiogenesis plays a pivotal role in the growth and metastasis of tumors.

肿瘤血管生成在肿瘤的生长和转移中起着重要的作用。

2.To investigate the correlation between the dynamic MRI enhancement characteristics and tumor angiogenesis in gastric carcinoma.

探讨胃癌动态增强MRI强化表现与肿瘤血管生成的关系。

3.Angiogenesis is vital for all body tissues: Without access to functioning blood vessels and their life-sustaining stream of oxygen and nutrients, cells can't survive.

血管再生术对人体所有组织都是至关重要的：没有血管再生术，人体则丧失造血功能、维持生命的器官则无法获得氧气及养分，细胞无法存活。

4.Observing angiogenesis and other types of cell growth in three dimensions is critical because that is how such growth normally occurs, said Kamm.

卡姆说，观测血管和其他类型的细胞的三维生长是至关重要的，因为这就是细胞生长通常是如何发生的。

5.The versatile compound is endostatin, a human protein that inhibits angiogenesis, the growth of new blood vessels in the body.

这种多功能化合物是内皮抑制素，一种抑制血管生成，即身体内新血管生长的人体蛋白质。

6.In the past 40 years, scientists have pinpointed more than a dozen proteins, known as growth factors, that appear to be involved in angiogenesis.

在过去的40年里，科学家已明确指出，有超过一半以上的蛋白质作为生长因子，出现于血管再生活动中。

7.In diabetic patients, abnormal angiogenesis can lead to complications.

在糖尿病患者中，异常的血管生成可能导致并发症。

8.Understanding angiogenesis is crucial for developing effective therapies.

理解血管生成对开发有效疗法至关重要。

9.Researchers are studying the role of angiogenesis in cancer progression.

研究人员正在研究血管生成在癌症进展中的作用。

10.Certain drugs target angiogenesis to prevent the growth of new blood vessels.

某些药物针对血管生成以防止新血管的生长。

11.The inhibition of angiogenesis could be a potential strategy for treating tumors.

抑制血管生成可能是治疗肿瘤的一种潜在策略。

作文

Angiogenesis is a critical biological process that involves the formation of new blood vessels from pre-existing ones. This phenomenon is not only essential for normal physiological functions but also plays a significant role in various pathological conditions. Understanding angiogenesis (血管生成) can provide insights into the mechanisms of diseases such as cancer, diabetes, and cardiovascular disorders.The process of angiogenesis begins when certain signals are released by cells in need of additional blood supply. These signals can be growth factors like Vascular Endothelial Growth Factor (VEGF), which stimulate endothelial cells to proliferate and migrate. As these cells come together, they form new capillary structures that eventually connect with existing blood vessels, creating a network that enhances oxygen and nutrient delivery to tissues.In healthy individuals, angiogenesis is tightly regulated to ensure that tissues receive adequate blood supply during growth, wound healing, and tissue repair. For instance, during pregnancy, angiogenesis is crucial for the development of the placenta, which provides nutrients and oxygen to the developing fetus. Similarly, when injuries occur, angiogenesis helps to restore blood flow to damaged areas, facilitating healing.However, the same process that is beneficial in normal physiology can become detrimental in certain disease states. In cancer, for example, tumors often secrete high levels of angiogenic factors, leading to excessive angiogenesis. This allows tumors to grow rapidly and metastasize by providing them with the necessary blood supply. The presence of new blood vessels can also create a favorable environment for tumor cells to thrive, making it more challenging to treat the disease effectively.Research into angiogenesis has led to the development of therapeutic strategies aimed at inhibiting this process in cancer treatment. Anti-angiogenic therapies, such as monoclonal antibodies targeting VEGF, have been designed to cut off the blood supply to tumors, thereby slowing their growth and spread. These treatments represent a significant advancement in oncology, offering new hope for patients with advanced-stage cancers.On the other hand, insufficient angiogenesis can also lead to complications. For instance, in conditions such as ischemic heart disease, where blood flow to the heart is restricted, promoting angiogenesis could help restore blood supply and improve heart function. Researchers are exploring various methods to enhance angiogenesis in such cases, including gene therapy and stem cell therapy, to stimulate the growth of new blood vessels in affected areas.In conclusion, angiogenesis (血管生成) is a vital process that plays a dual role in health and disease. While it is essential for normal bodily functions, its dysregulation can contribute to serious health issues, particularly in cancer. Ongoing research continues to unravel the complexities of angiogenesis and its implications for various diseases, paving the way for innovative treatments that harness this biological process for therapeutic benefit.