transcriptional

简明释义

英[trænˈskrɪpʃənl]美[trænˈskrɪpʃənl]

转录的

英英释义

单词用法

同义词

反义词

例句

1.Objective to study the effect of E2F1 transcription factor on the transcriptional activity of basic transcriptional regulatory region in the ARF promoter of MTS1 gene.

目的研究MTS1基因arf启动子基础转录调控区的转录激活及其与E2 F1转录因子之间的关系。

2.GPBF is the first report of transcriptional factor of GA biosynthesis-related in maize.

本研究的GPBF基因为玉米中首次报道的GA合成相关转录因子。

3.Recent studies have shown that interaction partners can modulate the transcriptional activity of AP-2 over the downstream targets.

最近的研究表明，AP-2能通过与其他蛋白的相互作用来调控AP-2下游基因的转录活性。

4.BRD7 was identified as a novel gene tightly associated to nasopharyngeal carcinoma (NPC) and also a nuclear transcriptional regulatory factor.

BRD7被鉴定为一个鼻咽癌密切相关新基因和潜在的核转录调节因子。

5.Transcriptional control is an important way of regulating of gene expression.

转录调控是基因表达调控的重要方式。

6.The DNA segments which have certain regulatory function in genomic sequences are called transcriptional regulatory elements.

基因组中具有调控功能的DNA序列片段可称为转录调控元件。

7.To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.

为了了解LXR如何调节低密度脂蛋白受体，作者研究了LXR靶基因的转录，并确定了一个能编码肌球蛋白互动蛋白的基因，IDOL。

8.Researchers discovered a new transcriptional factor that influences cell differentiation.

研究人员发现了一种新的转录因子，它影响细胞分化。

9.The experiment revealed changes in transcriptional profiles under stress conditions.

实验揭示了在压力条件下转录谱的变化。

10.The transcriptional activity of the gene was measured using a reporter assay.

该基因的转录活性是通过报告基因检测来测量的。

11.Understanding transcriptional networks can help in developing targeted therapies.

理解转录网络可以帮助开发靶向疗法。

12.The study focused on the transcriptional regulation of genes involved in cancer progression.

这项研究集中在与癌症进展相关的基因的转录调控上。

作文

In the fascinating world of molecular biology, the term transcriptional (转录的) regulation plays a crucial role in understanding how genes are expressed. At its core, transcription is the process by which the information in a gene's DNA sequence is transferred to messenger RNA (mRNA). This mRNA then serves as a template for protein synthesis, making transcriptional regulation vital for cellular function and development. The complexity of transcriptional (转录的) regulation can be attributed to various factors that influence how and when genes are turned on or off. These factors include transcription factors, which are proteins that bind to specific DNA sequences, enhancing or repressing the transcription of target genes. For instance, in response to environmental changes, certain transcription factors may activate genes that help the cell adapt, showcasing the dynamic nature of transcriptional (转录的) control.Moreover, the chromatin structure also plays a significant role in transcriptional (转录的) regulation. Chromatin is made up of DNA and proteins, and its configuration can either promote or inhibit access to the DNA for transcription machinery. When chromatin is tightly packed, genes are often silenced, while a more relaxed structure allows for active transcription. Understanding these mechanisms provides insight into how cells differentiate and respond to stimuli.In recent years, advances in technology have allowed scientists to explore transcriptional (转录的) regulation on a genome-wide scale. Techniques such as RNA sequencing enable researchers to quantify gene expression levels across different conditions, revealing intricate patterns of regulation. This has profound implications for fields such as cancer research, where abnormal transcriptional (转录的) activity can lead to uncontrolled cell growth. By identifying specific transcriptional networks that are disrupted in cancer cells, targeted therapies can be developed to restore normal gene expression patterns.Furthermore, the study of transcriptional (转录的) regulation extends beyond individual genes. It encompasses entire pathways and networks that govern cellular behavior. For instance, during development, specific genes must be activated or repressed at precise times to ensure proper formation of tissues and organs. Disruptions in these transcriptional (转录的) processes can result in developmental disorders or diseases.In conclusion, the concept of transcriptional (转录的) regulation is fundamental to our understanding of biology. It highlights the intricate controls that govern gene expression and the importance of this regulation in health and disease. As research continues to unveil the complexities of transcriptional (转录的) mechanisms, we gain valuable insights that could lead to innovative treatments for various diseases, emphasizing the significance of this field in modern science.

在分子生物学的迷人世界中，术语transcriptional（转录的）调控在理解基因如何表达方面发挥着至关重要的作用。其核心是，转录是将基因DNA序列中的信息转移到信使RNA（mRNA）的过程。这种mRNA随后作为蛋白质合成的模板，使得转录调控对细胞功能和发育至关重要。transcriptional（转录的）调控的复杂性可以归因于影响基因开启或关闭的各种因素。这些因素包括转录因子，这是一类能够结合特定DNA序列的蛋白质，从而增强或抑制目标基因的转录。例如，响应环境变化时，某些转录因子可能激活帮助细胞适应的基因，展示了transcriptional（转录的）控制的动态特性。此外，染色质结构在transcriptional（转录的）调控中也发挥着重要作用。染色质由DNA和蛋白质组成，其构型可以促进或抑制转录机器对DNA的访问。当染色质紧密打包时，基因通常会沉默，而更松弛的结构则允许活跃的转录。理解这些机制为我们提供了细胞如何分化和响应刺激的见解。近年来，技术的进步使科学家能够在全基因组范围内探索transcriptional（转录的）调控。像RNA测序这样的技术使研究人员能够量化不同条件下的基因表达水平，从而揭示复杂的调控模式。这对癌症研究等领域具有深远的影响，因为异常的transcriptional（转录的）活性可能导致细胞的失控生长。通过识别在癌细胞中被破坏的特定转录网络，可以开发针对性的治疗方法，以恢复正常的基因表达模式。此外，transcriptional（转录的）调控的研究超越了单个基因。它涵盖了支配细胞行为的整个通路和网络。例如，在发育过程中，特定基因必须在精确的时间激活或抑制，以确保组织和器官的正确形成。这些transcriptional（转录的）过程中的中断可能导致发育障碍或疾病。总之，transcriptional（转录的）调控的概念是我们理解生物学的基础。它突出了控制基因表达的复杂控制机制以及这种调控在健康和疾病中的重要性。随着研究继续揭示transcriptional（转录的）机制的复杂性，我们获得了宝贵的见解，这可能导致各种疾病的创新治疗，强调了这一领域在现代科学中的重要性。