sulfonylureas

简明释义

英[sʌl fəʊ nɪl ˈjʊə rɪ əz]美[sʌl fəˈnɪl ˈjʊr i əz]

n. （美）磺脲类（sulfonylurea 的复数形式，等于 sulphonylurea）；磺酰脲类药物

英英释义

单词用法

同义词

反义词

例句

1.Objective To research the effects of short-term intensive insulin treatment on regaining the sensitivity of sulfonylureas in diabetes patients.

目的探讨胰岛素短期强化治疗恢复糖尿患者对磺脲类药物的敏感性。

2.There are differences in mechanism of action certainly but the bottom line is that we know it works as well as sulfonylureas and I believe that has been the consensus from clinical experience.

两类药物的作用机制是不同的，但至少我们知道DPP - 4抑制剂和磺脲类同样有效，我想这也是临床经验得到的共识。

3.AIM To prepare a serious new coumarin-6-sulfonylureas.

目的合成新的香豆素磺酰脲类化合物供药理筛选。

4.There are differences in mechanism of action certainly but the bottom line is that we know it works as well as sulfonylureas and I believe that has been the consensus from clinical experience.

两类药物的作用机制是不同的，但至少我们知道DPP - 4抑制剂和磺脲类同样有效，我想这也是临床经验得到的共识。

5.This is not to say I would never use sulfonylureas, but simply that we need to have available to physicians and patients many different therapies.

这不是说我不会使用磺脲类药物，而只是说我们需要医生和患者能够获得多种不同的治疗。

6.When initiating oral antidiabetic therapy in newly diagnosed T2DM patients, physicians always recommend to use metformin over sulfonylureas.

医生最初应用口服降糖药治疗新诊断2型糖尿病时，往往被建议应用二甲双胍而非磺脲类。

7.International diabetes: Professor Pan, when we talk about GLP 1 and we talk about the effects medications what are the advantages to these agents when compared to traditional sulfonylureas?

《国际糖尿病》：潘教授，当我们谈及GLP -1以及药物效应时，与传统磺脲类药物相比，这些药物的优点是什么？

8.Prof Bloomgarden: Another effect of the incretin-based therapies would simply be to allow patients to not use sulfonylureas.

肠促胰岛素相关治疗的另一个作用简单地说就是可以使患者不使用磺脲类药物。

9.Patients may experience weight gain as a side effect of using sulfonylureas.

患者可能会因使用磺酰脲类药物而出现体重增加的副作用。

10.Patients taking sulfonylureas should monitor their blood glucose regularly to avoid hypoglycemia.

服用磺酰脲类药物的患者应定期监测血糖，以避免低血糖。

11.It is important for patients to discuss potential interactions when taking sulfonylureas with other medications.

患者在与其他药物一起服用磺酰脲类药物时，讨论潜在的相互作用是很重要的。

12.Some common examples of sulfonylureas include glipizide and glyburide.

一些常见的磺酰脲类药物包括格列吡嗪和格列本脲。

13.Doctors often prescribe sulfonylureas for patients with type 2 diabetes to help lower blood sugar levels.

医生常常为2型糖尿病患者开处方磺酰脲类药物以帮助降低血糖水平。

作文

In the realm of diabetes management, one of the most significant classes of medications is known as sulfonylureas. These drugs play a crucial role in controlling blood sugar levels for individuals with type 2 diabetes. Understanding how sulfonylureas work and their impact on health can help patients make informed decisions about their treatment options.Sulfonylureas are a group of oral hypoglycemic agents that stimulate the pancreas to release more insulin. This increase in insulin production helps lower blood glucose levels, which is essential for managing diabetes. Medications in this class include glipizide, glyburide, and glimepiride. Each of these drugs has its unique characteristics, but they all share the common mechanism of action that enhances insulin secretion.One of the advantages of sulfonylureas is their ability to provide relatively quick results. Patients often experience a noticeable decrease in their blood sugar levels shortly after starting treatment. This rapid response can be motivating for individuals who are struggling to manage their diabetes effectively. However, it is important to note that while sulfonylureas can be effective, they are not without risks.A significant concern associated with sulfonylureas is the potential for hypoglycemia, or low blood sugar. This condition can occur if a patient takes too much medication, skips meals, or engages in excessive physical activity. Symptoms of hypoglycemia include dizziness, confusion, sweating, and even loss of consciousness in severe cases. Therefore, patients must work closely with their healthcare providers to determine the appropriate dosage and monitor their blood sugar levels regularly.Another consideration when using sulfonylureas is weight gain. Some patients may experience an increase in body weight while on these medications, which can be counterproductive for those with type 2 diabetes, as maintaining a healthy weight is often a critical component of managing the condition. Lifestyle modifications, including diet and exercise, should be emphasized alongside medication therapy to mitigate this risk.Despite these drawbacks, sulfonylureas remain a popular choice for many healthcare providers due to their effectiveness and ease of use. They are often prescribed as a first-line treatment for type 2 diabetes, especially when lifestyle changes alone have not achieved adequate glycemic control. Furthermore, sulfonylureas can be used in combination with other diabetes medications to enhance overall treatment efficacy.In conclusion, sulfonylureas are an important tool in the management of type 2 diabetes. Their ability to stimulate insulin production makes them effective for lowering blood sugar levels. However, patients must be aware of the potential risks, such as hypoglycemia and weight gain, and should work closely with their healthcare providers to ensure safe and effective use. By understanding the role of sulfonylureas in diabetes management, patients can take proactive steps toward better health and improved quality of life.Overall, education about sulfonylureas and their implications is vital for anyone diagnosed with diabetes. With the right knowledge and support, individuals can navigate their treatment journey with confidence and achieve optimal blood sugar control.

在糖尿病管理领域，最重要的药物类别之一被称为sulfonylureas。这些药物在控制2型糖尿病患者的血糖水平方面发挥着至关重要的作用。了解sulfonylureas的工作原理及其对健康的影响可以帮助患者做出明智的治疗选择。Sulfonylureas是一组口服降糖药，通过刺激胰腺分泌更多的胰岛素来降低血糖。这种胰岛素分泌的增加有助于降低血糖水平，这对于管理糖尿病至关重要。该类药物包括格列吡嗪、格列本脲和格列美脲。虽然这些药物各有其独特的特点，但它们都共享增强胰岛素分泌的共同机制。Sulfonylureas的一个优点是它们能够提供相对快速的结果。患者在开始治疗后通常会明显降低血糖水平。这种快速反应可以激励那些在有效管理糖尿病方面挣扎的个体。然而，需要注意的是，虽然sulfonylureas可能有效，但并非没有风险。与sulfonylureas相关的一个重大问题是低血糖的潜在风险。如果患者服用过量药物、跳过餐食或进行过度的体育活动，可能会发生这种情况。低血糖的症状包括头晕、困惑、出汗，甚至在严重情况下失去意识。因此，患者必须与医疗提供者密切合作，以确定适当的剂量并定期监测血糖水平。使用sulfonylureas时的另一个考虑因素是体重增加。一些患者在服用这些药物时可能会体重增加，这对于那些有2型糖尿病的人来说可能是适得其反，因为维持健康体重通常是管理这一疾病的关键组成部分。生活方式的改变，包括饮食和锻炼，应该与药物治疗一起强调，以减轻这一风险。尽管存在这些缺点，sulfonylureas仍然是许多医疗提供者的热门选择，因为它们有效且易于使用。它们通常作为2型糖尿病的一线治疗方案，尤其是在单靠生活方式改变未能实现足够的血糖控制时。此外，sulfonylureas可以与其他糖尿病药物联合使用，以增强整体治疗效果。总之，sulfonylureas是管理2型糖尿病的重要工具。它们刺激胰岛素产生的能力使其在降低血糖水平方面有效。然而，患者必须意识到潜在的风险，如低血糖和体重增加，并应与医疗提供者密切合作，以确保安全有效的使用。通过了解sulfonylureas在糖尿病管理中的作用，患者可以采取积极措施，改善健康和生活质量。总体而言，关于sulfonylureas及其影响的教育对于任何被诊断为糖尿病的人来说都是至关重要的。凭借正确的知识和支持，个人可以自信地导航他们的治疗旅程，实现最佳的血糖控制。